Health Terms starting with 1
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1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN...
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt - A colorimetric reagent for iron, manganese, titanium, molybdenum, and complexes of zirconium. (From ...
1,2-Dimethylhydrazine - A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce co...
1,2-Dipalmitoylphosphatidylcholine - Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is als...
1,4-alpha-Glucan Branching Enzyme - In glycogen or amylopectin synthesis, the enzyme that catalyzes the transfer of a segment of a 1,4-a...
11-beta-Hydroxysteroid Dehydrogenase Type 1 - A low-affinity 11 beta-hydroxysteroid dehydrogenase found in a variety of tissues, most notably in L...
11-beta-Hydroxysteroid Dehydrogenase Type 2 - An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to c...
11-beta-Hydroxysteroid Dehydrogenases - Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive m...
11-Hydroxycorticosteroids - A group of corticosteroids bearing a hydroxy group at the 11-position....
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opio...
14-3-3 Proteins - A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They ar...
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions includ...
15-Oxoprostaglandin 13-Reductase - (5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active...
16,16-Dimethylprostaglandin E2 - A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promot...
17-alpha-Hydroxypregnenolone - A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an in...
17-alpha-Hydroxyprogesterone - A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an interme...
17-Hydroxycorticosteroids - A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of t...
17-Hydroxysteroid Dehydrogenases - A class of enzymes that catalyzes the oxidation of 17-hydroxysteroids to 17-ketosteroids. EC 1.1.-....
17-Ketosteroids - Steroids that contain a ketone group at position 17....
18-Hydroxycorticosterone - 11 beta,18,21-Trihydroxypregn-4-ene-3,20-dione....
18-Hydroxydesoxycorticosterone - An analog of desoxycorticosterone which is substituted by a hydroxyl group at the C-18 position....
19-Iodocholesterol - 19-Iodocholest-5-en-3 beta-ol. A cholesterol derivative usually substituted with radioactive iodine ...
1-Acylglycerol-3-Phosphate O-Acyltransferase - An enzyme that catalyzes the acyl group transfer of ACYL COA to 1-acyl-sn-glycerol 3-phosphate to ge...
1-Acylglycerophosphocholine O-Acyltransferase - An enzyme localized predominantly within the plasma membrane of lymphocytes. It catalyzes the transf...
1-Alkyl-2-acetylglycerophosphocholine Esterase - A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR b...
1-Carboxyglutamic Acid - Found in various tissues, particularly in four blood-clotting proteins including prothrombin, in kid...
1-Deoxynojirimycin - An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-...
1-Methyl-3-isobutylxanthine - A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases c...
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological ...
1-Methyl-4-phenylpyridinium - An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduce...
1-Naphthylamine - A suspected industrial carcinogen (and listed as such by OSHA). Its N-hydroxy metabolite is strongly...
1-Naphthylisothiocyanate - A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bil...
1-Octanol - A colorless, slightly viscous liquid used as a defoaming or wetting agent. It is also used as a solv...
1-Phosphatidylinositol 3-Kinase - An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate....
1-Phosphatidylinositol 4-Kinase - An enzyme that catalyzes the conversion of phosphatidylinositol (PHOSPHATIDYLINOSITOLS) to phosphati...
1-Propanol - A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemica...
1-Pyrroline-5-Carboxylate Dehydrogenase - An enzyme that catalyzes the oxidation of 1-pyrroline-5-carboxylate to L-GLUTAMATE in the presence o...
1-Sarcosine-8-Isoleucine Angiotensin II - An ANGIOTENSIN II analog which acts as a highly specific inhibitor of ANGIOTENSIN TYPE 1 RECEPTOR....
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
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Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
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Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.