Thyroxine
Definition
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from THYROGLOBULIN by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Annotations
/blood: consider also HYPERTHYROXINEMIA
Other Entries
L-Thyroxine
Levothyroxine
T4 Thyroid Hormone
3,5,3',5'-Tetraiodothyronine
Abbot Brand of Levothyroxine Sodium
Allphar Brand of Levothyroxine Sodium
Aventis Brand of Levothyroxine Sodium
Berlin-Chemie Brand of Levothyroxine Sodium
Berlthyrox
Byk Brand of Levothyroxine Sodium
Delalande Brand of Levothyroxine Sodium
Dexnon
Eferox
Eltroxin
Eltroxine
Euthyrox
Eutirox
Forest Brand of Levothyroxine Sodium
Genpharm Brand of Levothyroxine Sodium
GlaxoSmithKline Brand of Levothyroxine Sodium
GlaxoWellcome Brand of Levothyroxine Sodium
Goldshield Brand of Levothyroxine Sodium
Henning Berlin Brand of Levothyroxine Sodium
Hexal Brand 1 of Levothyroxine Sodium
Hexal Brand 2 of Levothyroxine Sodium
Kern Brand of Levothyroxine Sodium
L-3,5,3',5'-Tetraiodothyronine
L-Thyrox
L-Thyroxin Henning
L-Thyroxin beta
L-Thyroxine Roche
Levo-T
Levothroid
Levothyroid
Levothyroxin Deladande
Levothyroxin Delalande
Levothyroxine Sodium
Levoxine
Levoxyl
Lévothyrox
Merck Brand of Levothyroxine Sodium
Merck Lipha Santé Brand of Levothyroxine Sodium
Monarch Brand of Levothyroxine Sodium
Mova Brand of Levothyroxine Sodium
Nourypharma Brand of Levothyroxine Sodium
Novothyral
Novothyrox
O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
Oroxine
Roche Brand of Levothyroxine Sodium
Rudefsa Brand of Levothyroxine Sodium
Sanofi Synthelabo Brand of Levothyroxine Sodium
Sigma Brand of Levothyroxine Sodium
Sodium Levothyroxine
Synthroid
Synthrox
Thevier
Thyrax
Thyroxin
Tiroidine
Tiroxina Leo
Unithroid
Vortex Brand of Levothyroxine Sodium
Watson Brand of Levothyroxine Sodium
betapharm Brand of Levothyroxine Sodium
Berlin Chemie Brand of Levothyroxine Sodium
Deladande, Levothyroxin
Delalande, Levothyroxin
L Thyrox
L Thyroxin Henning
L Thyroxin beta
L Thyroxine
L Thyroxine Roche
LThyroxin Henning
LThyroxin beta
Leo, Tiroxina
Levo T
LevoT
Thyroid Hormone, T4
Allowable Qualifiers
administration & dosage adverse effects agonists analogs & derivatives analysis antagonists & inhibitors biosynthesis blood cerebrospinal fluid chemical synthesis chemistry classification contraindications deficiency diagnostic use drug effects economics genetics history immunology isolation & purification metabolism pharmacokinetics pharmacology physiology poisoning radiation effects secretion standards supply & distribution therapeutic use toxicity urine
Categories
Entry Date
01-01-1999
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Diabetes Supplies | Diabetic Groups
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Free Diabetes Supplies
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
