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Macrocyclic Compounds

Categorical breakdown of terms falling inder the category of Macrocyclic Compounds. Sub categories will become more specific in nature to the terms listed for Macrocyclic Compounds.

Sub-Categories

Terms

Alamethicin - A cyclic nonadecapeptide antibiotic that can act as an ionophore and is produced by strains of Trich...

Alpha-Amanitin - A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. It inhibits RNA POL...

alpha-Cyclodextrins - Cyclic GLUCANS consisting of six (6) glucopyranose units linked by 1,4-glycosidic bonds....

Amanitins - Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors o...

Amphotericin B - Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco r...

Antimycin A - An antibiotic substance produced by Streptomyces species. It inhibits mitochondrial respiration and ...

Azithromycin - A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the ...

Bacitracin - A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The com...

Bacteriochlorophylls - Pyrrole containing pigments found in photosynthetic bacteria....

Bacteriochlorophylls - Pyrrole containing pigments found in photosynthetic bacteria....

beta-Cyclodextrins - Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds....

Bile Pigments - Linear TETRAPYRROLES that give a characteristic color to BILE including: BILIRUBIN; BILIVERDIN; and ...

Bilirubin - A bile pigment that is a degradation product of HEME....

Biliverdine - 1,3,6,7-Tetramethyl-4,5-dicarboxyethyl-2,8-divinylbilenone. Biosynthesized from hemoglobin as a prec...

Brefeldin A - A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity....

Calixarenes - Phenolic metacyclophanes derived from condensation of PHENOLS and ALDEHYDES. The name derives from t...

Candicidin - Mixture of antifungal heptaene macrolides from Streptomyces griseus or Actinomyces levoris used topi...

Capreomycin - Cyclic peptide antibiotic similar to VIOMYCIN. It is produced by Streptomyces capreolus....

Chlorophyll - Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organi...

Chlorophyll - Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organi...

Chlorophyllides - Products of the hydrolysis of chlorophylls in which the phytic acid side chain has been removed and ...

Chlorophyllides - Products of the hydrolysis of chlorophylls in which the phytic acid side chain has been removed and ...

Clarithromycin - A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of m...

Colistin - Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or C...

Coproporphyrinogens - Porphyrinogens which are intermediates in the heme biosynthesis. They have four methyl and four prop...

Coproporphyrins - Porphyrins with four methyl and four propionic acid side chains attached to the pyrrole rings. Eleva...

Corrinoids - Cyclic TETRAPYRROLES based on the corrin skeleton....

Crown Compounds - Macrocyclic compounds analogous to CROWN ETHERS but which lack any OXYGEN atoms....

Crown Ethers - Macrocyclic polyethers with the repeating unit of (-CH2-CH2-O)n where n is greater than 2 and some o...

Crown Ethers - Macrocyclic polyethers with the repeating unit of (-CH2-CH2-O)n where n is greater than 2 and some o...

Cyclodextrins - A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the act...

Cycloparaffins - Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a r...

Cyclosporine - A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a speci...

Cyclosporins - A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindoca...

Cytochalasin B - A cytotoxic member of the CYTOCHALASINS....

Cytochalasin D - A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilam...

Cytochalasins - 11- to 14-membered macrocyclic lactones with a fused isoindolone. Members with INDOLES attached at t...

Dactinomycin - A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOM...

Daptomycin - A cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA....

Depsipeptides - Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide ...

Deuteroporphyrins - Porphyrins with four methyl and two propionic acid side chains attached to the pyrrole rings....

Dihematoporphyrin Ether - The purified component of HEMATOPORPHYRIN DERIVATIVE, it consists of a mixture of oligomeric porphyr...

Echinomycin - A cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DN...

Enterobactin - An iron-binding cyclic trimer of 2,3-dihydroxy-N-benzoyl-L-serine. It is produced by E COLI and othe...

Enviomycin - Cyclic basic peptide related to VIOMYCIN. It is isolated from an induced mutant of Streptomyces gris...

Epothilones - A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They...

Erythromycin - A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is consider...

Erythromycin Estolate - A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the pro...

Erythromycin Ethylsuccinate - A macrolide antibiotic, produced by Streptomyces erythreus. This compound is an ester of erythromyci...

Ethers, Cyclic - Compounds of the general formula R-O-R arranged in a ring or crown formation....

Etioporphyrins - Porphyrins with four methyl and four ethyl side chains attached to the pyrrole rings....

Ferrichrome - A cyclic peptide consisting of three residues of delta-N-hydroxy-delta-N-acetylornithine. It acts as...

Filipin - A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membran...

gamma-Cyclodextrins - Cyclic GLUCANS consisting of eight (8) glucopyranose units linked by 1,4-glycosidic bonds....

Gramicidin - A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid p...

Hematoporphyrin Derivative - A complex mixture of monomeric and aggregated porphyrins used in the photodynamic therapy of tumors ...

Hematoporphyrins - Iron-free derivatives of heme with 4 methyl groups, 2 hydroxyethyl groups and 2 propionic acid group...

Heme - The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group ...

Hemin - Chloro(7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N(21),N(22),N(23)...

Hydroxocobalamin - Injectable form of VITAMIN B 12 that has been used therapeutically to treat VITAMIN B 12 DEFICIENCY....

Ivermectin - A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), wh...

Josamycin - A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a ...

Ketolides - Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of...

Kitasamycin - A macrolide antibiotic produced by Streptomyces kitasatoensis. The drug has antimicrobial activity a...

Lactams, Macrocyclic - LACTAMS forming compounds with a ring size of approximately 1-3 dozen atoms....

Leucomycins - An antibiotic complex produced by Streptomyces kitasatoensis. The complex consists of a mixture of a...

Lucensomycin - A macrolide isolated from cultures of Streptomyces lucensis....

Macrocyclic Compounds - Cyclic compounds with a ring size of approximately 1-4 dozen atoms....

Macrolides - A group of macrocyclic compounds formed by chain extension of multiple PROPIONATES and cyclized into...

Maytansine - An ansa macrolide isolated from the MAYTENUS genus of East African shrubs....

Mepartricin - Polyene macrolide antibiotic with unknown composition. It is obtained from Streptomyces aureofaciens...

Mesoporphyrins - Porphyrins with four methyl, two ethyl, and two propionic acid side chains attached to the pyrrole r...

Metalloporphyrins - Porphyrins which are combined with a metal ion. The metal is bound equally to all four nitrogen atom...

Microcystins - Cyclic heptapeptides found in MICROCYSTIS and other CYANOBACTERIA. Hepatotoxic and carcinogenic effe...

Mikamycin - An antibiotic complex originally isolated from Streptomyces mitakaenis. It contains two principle in...

Miocamycin - A macrolide antibiotic that has a wide antimicrobial spectrum and is particularly effective in respi...

Mycobacillin - A cyclic polypeptide antibiotic isolated from culture filtrates of Bacillus subtilis that acts as an...

Natamycin - Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is...

Nisin - A 34-amino acid polypeptide antibiotic produced by Streptococcus lactis. It has been used as a food ...

Nystatin - Macrolide antifungal antibiotic complex produced by Streptomyces noursei, S. aureus, and other Strep...

Octreotide - A potent, long-acting synthetic SOMATOSTATIN octapeptide analog that inhibits secretion of GROWTH HO...

Oleandomycin - Antibiotic macrolide produced by Streptomyces antibioticus....

Oligomycins - A closely related group of toxic substances elaborated by various strains of Streptomyces. They are ...

Peptides, Cyclic - Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular cha...

Phalloidine - Very toxic polypeptide isolated mainly from AMANITA phalloides (Agaricaceae) or death cup; causes fa...

Pheophytins - Chlorophylls from which the magnesium has been removed by treatment with weak acid....

Phycobilins - Open chain tetrapyrroles that function as light harvesting chromophores in PHYCOBILIPROTEINS....

Polymyxin B - A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypepti...

Polymyxins - Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by...

Porphyrinogens - Colorless reduced precursors of porphyrins in which the pyrrole rings are linked by methylene (-CH2-...

Porphyrins - A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridg...

Pristinamycin - An antibiotic mixture originally isolated from Streptomyces pristinaspiralis. It is a mixture of com...

Protochlorophyllide - A photo-active pigment localized in prolamellar bodies occurring within the proplastids of dark-grow...

Protochlorophyllide - A photo-active pigment localized in prolamellar bodies occurring within the proplastids of dark-grow...

Protoporphyrins - Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole r...

Rifabutin - A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avi...

Rifampin - A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spe...

Rifamycins - A group of ANTI-BACTERIAL AGENTS characterized by a chromophoric naphthohydroquinone group spanned b...

Roxithromycin - Semisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive in...

Rutamycin - A macrolide antibiotic of the oligomycin group, obtained from Streptomyces rutgersensis. It is used ...

Sirolimus - A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the ...

Spiramycin - A macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-posi...

Streptogramin A - A specific streptogramin group A antibiotic produced by Streptomyces graminofaciens and other bacter...

Streptogramin A - A specific streptogramin group A antibiotic produced by Streptomyces graminofaciens and other bacter...

Streptogramin B - A specific streptogramin group B antibiotic produced by Streptomyces graminofaciens and other bacter...

Streptogramin Group A - A structural subclass of streptogramins that includes molecules containing unsaturated macrocyclic l...

Streptogramin Group B - A structural subclass of streptogramins. They are cyclic hexadepsipeptides with approximate molecula...

Streptogramins - A class of natural cyclic peptide antibiotics produced by certain subspecies of STREPTOMYCES. They i...

Streptovaricin - A complex of ansamycin antibiotics consisting of streptovaricins A, B, C, D, E, F, G, J, and K of wh...

T-2 Toxin - A potent mycotoxin produced in feedstuffs by several species of the genus FUSARIUM. It elicits a sev...

Tacrolimus - A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong...

Tetrapyrroles - Four PYRROLES joined by one-carbon units linking position 2 of one to position 5 of the next. The co...

Thiostrepton - One of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veter...

Trichodermin - Antifungal metabolite from several fungi, mainly Trichoderma viride; inhibits protein synthesis by b...

Trichothecenes - Usually 12,13-epoxytrichothecenes, produced by Fusaria, Stachybotrys, Trichoderma and other fungi, a...

Troleandomycin - A macrolide antibiotic that is similar to ERYTHROMYCIN....

Tylosin - Macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against m...

Tyrocidine - An antibiotic mixture produced by Bacillus brevis which may be separated into three components, tyro...

Tyrothricin - A polypeptide antibiotic mixture obtained from Bacillus brevis. It consists of a mixture of three ty...

Urobilinogen - A colorless compound formed in the intestines by the reduction of bilirubin. Some is excreted in the...

Uroporphyrinogens - Porphyrinogens which are intermediates in heme biosynthesis. They have four acetic acid and four pro...

Uroporphyrins - Porphyrins with four acetic acid and four propionic acid side chains attached to the pyrrole rings....

Valinomycin - A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to t...

Vernamycin B - An antibiotic mixture originally isolated from Streptomyces loidensis. It contains a mixture of comp...

Viomycin - A strongly basic peptide, antibiotic complex from several strains of Streptomyces. It is allergenic ...

Virginiamycin - A cyclic polypeptide antibiotic complex from Streptomyces virginiae, S. loidensis, S. mitakaensis, S...

Vitamin B 12 - A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in s...