Neurodegenerative Diseases
Categorical breakdown of terms falling inder the category of Neurodegenerative Diseases. Sub categories will become more specific in nature to the terms listed for Neurodegenerative Diseases.
Sub-Categories
Terms
Alexander Disease - A rare inherited disorder of myelin formation. Alexander disease is a progressive leukoencephalopath...
Alstrom Syndrome - Rare autosomal recessive disease characterized by multiple organ dysfunction. The key clinical featu...
Alzheimer Disease - A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of ...
Amyloid Neuropathies, Familial - Inherited disorders of the peripheral nervous system associated with the deposition of AMYLOID in ne...
Amyotrophic Lateral Sclerosis - A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the br...
Amyotrophic Lateral Sclerosis - A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the br...
Bulbar Palsy, Progressive - A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of...
Bulbo-Spinal Atrophy, X-Linked - An X-linked recessive form of spinal muscular atrophy. It is due to a mutation of the gene encoding ...
Bulbo-Spinal Atrophy, X-Linked - An X-linked recessive form of spinal muscular atrophy. It is due to a mutation of the gene encoding ...
Canavan Disease - A rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolizati...
Charcot-Marie-Tooth Disease - A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and ...
Cockayne Syndrome - A syndrome characterized by multiple system abnormalities including DWARFISM; PHOTOSENSITIVITY DISOR...
Diffuse Neurofibrillary Tangles with Calcification - A form of presenile DEMENTIA characterized by cortical dementia, NEUROFIBRILLARY TANGLES without SEN...
Dysautonomia, Familial - An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashk...
Dystonia Musculorum Deformans - A condition characterized by focal DYSTONIA that progresses to involuntary spasmodic contractions of...
Encephalopathy, Bovine Spongiform - A transmissible spongiform encephalopathy of cattle associated with abnormal prion proteins in the b...
Friedreich Ataxia - An autosomal recessive disease, usually of childhood onset, characterized pathologically by degenera...
Frontotemporal Dementia - The most common clinical form of FRONTOTEMPORAL LOBAR DEGENERATION, this dementia presents with pers...
Frontotemporal Lobar Degeneration - Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atroph...
Gerstmann-Straussler-Scheinker Disease - An autosomal dominant familial prion disease with a wide spectrum of clinical presentations includin...
Gerstmann-Straussler-Scheinker Disease - An autosomal dominant familial prion disease with a wide spectrum of clinical presentations includin...
Giant Axonal Neuropathy - Rare autosomal recessive disorder of INTERMEDIATE FILAMENT PROTEINS. The disease is caused by mutati...
Hepatolenticular Degeneration - A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CO...
Hereditary Central Nervous System Demyelinating Diseases - Inherited conditions characterized by a loss of myelin in the central nervous system....
Hereditary Sensory and Autonomic Neuropathies - A group of inherited disorders characterized by degeneration of dorsal root and autonomic ganglion c...
Hereditary Sensory and Motor Neuropathy - A group of slowly progressive inherited disorders affecting motor and sensory peripheral nerves. Sub...
Heredodegenerative Disorders, Nervous System - Inherited disorders characterized by progressive atrophy and dysfunction of anatomically or physiolo...
Huntington Disease - A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progr...
Insomnia, Fatal Familial - An autosomal dominant disorder characterized by degeneration of the THALAMUS and progressive insomni...
Kuru - A prion disease found exclusively among the Fore linguistic group natives of the highlands of NEW GU...
Lafora Disease - A form of stimulus sensitive myoclonic epilepsy inherited as an autosomal recessive condition. The m...
Lambert-Eaton Myasthenic Syndrome - An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly o...
Lesch-Nyhan Syndrome - An inherited disorder transmitted as a sex-linked trait and caused by a deficiency of an enzyme of p...
Lewy Body Disease - A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attent...
Limbic Encephalitis - A paraneoplastic syndrome marked by degeneration of neurons in the medial temporal lobe. Clinical fe...
Machado-Joseph Disease - A dominantly-inherited ATAXIA first described in people of Azorean and Portuguese descent, and subse...
Menkes Kinky Hair Syndrome - An inherited disorder of copper metabolism transmitted as an X-linked trait and characterized by the...
Motor Neuron Disease - Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainste...
Multiple System Atrophy - A syndrome complex composed of three conditions which represent clinical variants of the same diseas...
Muscular Atrophy, Spinal - A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resultin...
Myelitis, Transverse - Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental...
Myoclonic Cerebellar Dyssynergia - A condition marked by progressive CEREBELLAR ATAXIA combined with MYOCLONUS usually presenting in th...
Myotonia Congenita - A dominantly inherited muscle disease that begins in early childhood and is characterized by severe ...
Myotonic Dystrophy - An autosomal dominant neuromuscular disorder which usually presents in early adulthood, characterize...
Neurodegenerative Diseases - Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction...
Neurofibromatoses - A group of disorders characterized by an autosomal dominant pattern of inheritance with high rates o...
Neurofibromatosis 1 - An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that featu...
Neurofibromatosis 2 - An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as w...
Neuronal Ceroid-Lipofuscinoses - A group of severe neurodegenerative diseases characterized by intracellular accumulation of autofluo...
Olivopontocerebellar Atrophies - A group of inherited and sporadic disorders which share progressive ataxia in combination with atrop...
Olivopontocerebellar Atrophies - A group of inherited and sporadic disorders which share progressive ataxia in combination with atrop...
Olivopontocerebellar Atrophies - A group of inherited and sporadic disorders which share progressive ataxia in combination with atrop...
Opsoclonus-Myoclonus Syndrome - A neurological condition that is characterized by uncontrolled rapid irregular movements of the eye ...
Optic Atrophies, Hereditary - Hereditary conditions that feature progressive visual loss in association with optic atrophy. Relati...
Optic Atrophy, Autosomal Dominant - Dominant optic atrophy is a hereditary optic neuropathy causing decreased visual acuity, color visio...
Optic Atrophy, Hereditary, Leber - A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision l...
Pantothenate Kinase-Associated Neurodegeneration - A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolesc...
Paraneoplastic Cerebellar Degeneration - Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressi...
Paraneoplastic Polyneuropathy - A diffuse or multifocal peripheral neuropathy related to the remote effects of a neoplasm, most ofte...
Paraneoplastic Syndromes, Nervous System - Degenerative or inflammatory conditions affecting the central or peripheral nervous system that deve...
Parkinson Disease - A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, re...
Postpoliomyelitis Syndrome - A syndrome characterized by new neuromuscular symptoms that occur at least 15 years after clinical s...
Primary Progressive Nonfluent Aphasia - A form of frontotemporal lobar degeneration and a progressive form of dementia characterized by moto...
Prion Diseases - A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders a...
Refsum Disease - An autosomal recessive familial disorder that usually presents in childhood with POLYNEUROPATHY; SEN...
Rett Syndrome - An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and ma...
Scrapie - A fatal disease of the nervous system in sheep and goats, characterized by pruritus, debility, and l...
Shy-Drager Syndrome - A progressive neurodegenerative condition of the central and autonomic nervous systems characterized...
Shy-Drager Syndrome - A progressive neurodegenerative condition of the central and autonomic nervous systems characterized...
Spastic Paraplegia, Hereditary - A group of inherited diseases that share similar phenotypes but are genetically diverse. Different g...
Spinal Muscular Atrophies of Childhood - A group of recessively inherited diseases that feature progressive muscular atrophy and hypotonia. T...
Spinal Muscular Atrophies of Childhood - A group of recessively inherited diseases that feature progressive muscular atrophy and hypotonia. T...
Spinocerebellar Ataxias - A group of dominantly inherited, predominately late-onset, cerebellar ataxias which have been divide...
Spinocerebellar Degenerations - A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either i...
Striatonigral Degeneration - A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsoni...
Subacute Combined Degeneration - A neuropathy due to VITAMIN B 12 DEFICIENCY or to excessive NITROUS OXIDE inhalation. It is associat...
Supranuclear Palsy, Progressive - A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR M...
Tauopathies - Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in ...
TDP-43 Proteinopathies - Diseases characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-...
Tourette Syndrome - A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission in...
Tuberous Sclerosis - An autosomal dominant disorder which is generally classified as a phacomatosis. Pathologically, the ...
Unverricht-Lundborg Syndrome - An autosomal recessive condition characterized by recurrent myoclonic and generalized seizures, ATAX...
Wasting Disease, Chronic - A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic w...
Wolfram Syndrome - A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIA...
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
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Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
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Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.