Eicosanoids
Categorical breakdown of terms falling inder the category of Eicosanoids. Sub categories will become more specific in nature to the terms listed for Eicosanoids.
Sub-Categories
Terms
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opio...
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions includ...
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions includ...
16,16-Dimethylprostaglandin E2 - A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promot...
5,8,11,14-Eicosatetraynoic Acid - A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion o...
6-Ketoprostaglandin F1 alpha - The physiologically active and stable hydrolysis product of EPOPROSTENOL. Found in nearly all mammal...
6-Ketoprostaglandin F1 alpha - The physiologically active and stable hydrolysis product of EPOPROSTENOL. Found in nearly all mammal...
8,11,14-Eicosatrienoic Acid - A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic ac...
Alprostadil - A potent vasodilator agent that increases peripheral blood flow....
Arachidonic Acid - An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, b...
Arbaprostil - A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promot...
Carboprost - A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of PREG...
Cloprostenol - A synthetic prostaglandin F2alpha analog. The compound has luteolytic effects and is used for the sy...
Dinoprost - A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due...
Dinoprost - A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due...
Dinoprostone - The most common and most biologically active of the mammalian prostaglandins. It exhibits most biolo...
Dinoprostone - The most common and most biologically active of the mammalian prostaglandins. It exhibits most biolo...
Eicosanoids - A class of compounds named after and generally derived from C20 fatty acids (EICOSANOIC ACIDS) that ...
Eicosapentaenoic Acid - Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostagl...
Enprostil - A synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective ef...
Epoprostenol - A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesi...
Epoprostenol - A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesi...
F2-Isoprostanes - Isoprostanes derived from the free radical oxidation of ARACHIDONIC ACID. Although similar in struct...
Hydroxyeicosatetraenoic Acids - Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important...
Iloprost - An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stabl...
Isoprostanes - A series of prostaglandin-like compounds that are produced by the attack of free-radical species on ...
Leukotriene A4 - (2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable a...
Leukotriene B4 - The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cel...
Leukotriene C4 - The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metaboli...
Leukotriene D4 - One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partia...
Leukotriene E4 - A biologically active principle of SRS-A that is formed from LEUKOTRIENE D4 via a peptidase reaction...
Leukotrienes - A family of biologically active compounds derived from arachidonic acid by oxidative metabolism thro...
Lipoxins - Trihydroxy derivatives of eicosanoic acids. They are primarily derived from arachidonic acid, howeve...
Misoprostol - A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric aci...
Prostaglandin D2 - The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast ...
Prostaglandin D2 - The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast ...
Prostaglandin Endoperoxides - Precursors in the biosynthesis of prostaglandins and thromboxanes from arachidonic acid. They are ph...
Prostaglandin Endoperoxides - Precursors in the biosynthesis of prostaglandins and thromboxanes from arachidonic acid. They are ph...
Prostaglandin Endoperoxides, Synthetic - Synthetic compounds that are analogs of the naturally occurring prostaglandin endoperoxides and that...
Prostaglandin H2 - A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It ...
Prostaglandin H2 - A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It ...
Prostaglandins - A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via...
Prostaglandins - A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via...
Prostaglandins A - (13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid (PGA(1)); (5Z,13E,15S)-15-hydroxy-9-oxoprosta...
Prostaglandins A - (13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid (PGA(1)); (5Z,13E,15S)-15-hydroxy-9-oxoprosta...
Prostaglandins A, Synthetic - Analogs or derivatives of prostaglandin A that do not occur naturally in the body. They do not inclu...
Prostaglandins B - Physiologically active prostaglandins found in many tissues and organs. They are potent pressor subs...
Prostaglandins B - Physiologically active prostaglandins found in many tissues and organs. They are potent pressor subs...
Prostaglandins D - Physiologically active prostaglandins found in many tissues and organs. They show pressor activity, ...
Prostaglandins D - Physiologically active prostaglandins found in many tissues and organs. They show pressor activity, ...
Prostaglandins E - (11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15...
Prostaglandins E - (11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15...
Prostaglandins E, Synthetic - Analogs or derivatives of prostaglandins E that do not occur naturally in the body. They do not incl...
Prostaglandins F - (9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,a...
Prostaglandins F - (9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,a...
Prostaglandins F, Synthetic - Analogs or derivatives of prostaglandins F that do not occur naturally in the body. They do not incl...
Prostaglandins G - A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthes...
Prostaglandins G - A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthes...
Prostaglandins H - A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthes...
Prostaglandins H - A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthes...
Prostaglandins I - A class of cyclic prostaglandins that contain the 6,9-epoxy bond. Endogenous members of this family ...
Prostaglandins I - A class of cyclic prostaglandins that contain the 6,9-epoxy bond. Endogenous members of this family ...
Prostaglandins, Synthetic - Compounds obtained by chemical synthesis that are analogs or derivatives of naturally occurring pros...
Rioprostil - A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastr...
SRS-A - A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; H...
Thromboxane A2 - An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound ha...
Thromboxane B2 - A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is...
Thromboxanes - Physiologically active compounds found in many organs of the body. They are formed in vivo from the ...
Thromboxanes - Physiologically active compounds found in many organs of the body. They are formed in vivo from the ...
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
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Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
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Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
