Alkaloids
Categorical breakdown of terms falling inder the category of Alkaloids. Sub categories will become more specific in nature to the terms listed for Alkaloids.
Sub-Categories
Terms
1-Deoxynojirimycin - An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-...
Aconitine - A C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM plants. It activates voltage-ga...
Acridones - Compounds based on acridone, which have three linear rings, with the center ring containing a ring n...
Acronine - A pyrano-acridone alkaloid found in RUTACEAE plants....
Ajmaline - An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia a...
Alcuronium - A non-depolarizing skeletal muscle relaxant similar to TUBOCURARINE. It is used as an anesthesia adj...
Alkaloids - Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable ki...
Amaryllidaceae Alkaloids - Alkaloids derived from TYRAMINE combined with 3,4-dihydroxybenzaldehyde via a norbelladine pathway, ...
Anabasine - A piperidine botanical insecticide....
Apomorphine - A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used fo...
Aporphines - Dibenzoquinolines derived in plants from (S)-reticuline (BENZYLISOQUINOLINES)....
Arecoline - An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at b...
Atropine - An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE....
Atropine - An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE....
Atropine Derivatives - Analogs and derivatives of atropine....
Belladonna Alkaloids - Alkaloids obtained from various plants, especially the deadly nightshade (Atropa belladonna), variet...
Belladonna Alkaloids - Alkaloids obtained from various plants, especially the deadly nightshade (Atropa belladonna), variet...
Benzomorphans - Morphine derivatives of the methanobenzazocine family that act as potent analgesics....
Benzophenanthridines - Compounds of four rings containing a nitrogen. They are biosynthesized from reticuline via rearrange...
Benztropine - A centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSO...
Benzylisoquinolines - ISOQUINOLINES with a benzyl substituent....
Berberine - An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It i...
Berberine Alkaloids - A group of related plant alkaloids that contain the BERBERINE heterocyclic ring structure....
Betacyanins - Conjugates of betalamic acid with cyclo-dopa, both of which derive from TYROSINE. They appear simila...
Betalains - Compounds derived from TYROSINE via betalamic acid, including BETAXANTHINS and BETACYANINS. They are...
Betaxanthins - Conjugates of betalamic acid with AMINO ACIDS. Some of them are yellow COLORING AGENTS in the Caryop...
Bicuculline - Isoquinoline alkaloid from Dicentra cucullaria and other plants that is a competitive antagonist at ...
Bromocriptine - A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion...
Buprenorphine - A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than...
Butorphanol - A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of sev...
Butylscopolammonium Bromide - Antimuscarinic quaternary ammonium derivative of scopolamine used to treat cramps in gastrointestina...
Caffeine - A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caf...
Camptothecin - An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound se...
Capsaicin - An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS....
Cevanes - Structurally-related alkaloids that contain the cevane carbon backbone....
Cinchona Alkaloids - Alkaloids extracted from various species of Cinchona....
Cocaine - An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and v...
Codeine - An opioid analgesic related to MORPHINE but with less potent analgesic properties and mild sedative ...
Colchicine - A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary ...
Crack Cocaine - The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intraven...
Demecolcine - An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic....
Dextromethorphan - Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, inclu...
Dextrorphan - Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effect...
Dihydro-beta-Erythroidine - Dihydro analog of beta-erythroidine, which is isolated from the seeds and other plant parts of Eryth...
Dihydroergocornine - A 9,10alpha-dihydro derivative of ERGOTAMINE that contains isopropyl sidechains at the 2' and 5' pos...
Dihydroergocristine - A 9,10alpha-dihydro derivative of ERGOTAMINE that contains an isopropyl sidechain at the 2' position...
Dihydroergocryptine - A 9,10alpha-dihydro derivative of ERGOTAMINE that contains an isopropyl sidechain at the 2' position...
Dihydroergotamine - A 9,10alpha-dihydro derivative of ERGOTAMINE. It is used as a vasoconstrictor, specifically for the ...
Dihydroergotoxine - A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGO...
Dihydromorphine - A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential....
Diprenorphine - A narcotic antagonist similar in action to NALOXONE. It is used to remobilize animals after ETORPHIN...
Ellipticines - Pyrido-CARBAZOLES originally discovered in the bark of OCHROSIA ELLIPTICA. They inhibit DNA and RNA ...
Emetine - The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. ...
Ergolines - A series of structurally-related alkaloids that contain the ergoline backbone structure....
Ergoloid Mesylates - A mixture of the mesylates (methane sulfonates) of DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and the ...
Ergonovine - An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties....
Ergot Alkaloids - Alkaloids originally isolated from the ergot fungus Claviceps purpurea (Hypocreaceae). They include ...
Ergotamine - A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist an...
Ergotamines - A series of structurally-related alkaloids containing the ergotaman backbone structure....
Ethylmorphine - A narcotic analgesic and antitussive. It is metabolized in the liver by ETHYLMORPHINE-N-DEMETHYLASE ...
Etorphine - A narcotic analgesic morphinan used as a sedative in veterinary practice....
Galantamine - A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a ...
Germine Acetates - Germine derivatives acetylated on any one or more of the hydroxy groups. These compounds are present...
Harmaline - A beta-carboline alkaloid isolated from seeds of PEGANUM....
Harmine - Alkaloid isolated from seeds of Peganum harmala L., Zygophyllaceae. It is identical to banisterine, ...
Harringtonines - Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkal...
Heroin - A narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) list...
Hydrocodone - Narcotic analgesic related to CODEINE, but more potent and more addicting by weight. It is used also...
Hydromorphone - An opioid analgesic made from MORPHINE and used mainly as an analgesic. It has a shorter duration of...
Ibogaine - One of several indole alkaloids extracted from Tabernanthe iboga, Baill. It has a complex pharmacolo...
Indole Alkaloids - Group of alkaloids containing a benzylpyrrole group (derived from TRYPTOPHAN)...
Ipratropium - A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effecti...
Levallorphan - An opioid antagonist with properties similar to those of NALOXONE; in addition it also possesses som...
Levorphanol - A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection....
Lisuride - An ergot derivative that acts as an agonist at dopamine D2 receptors (DOPAMINE AGONISTS). It may als...
Lobeline - An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less pote...
Lumicolchicines - Three, alpha, beta, and gamma isomers of ultraviolet degradation products of colchicine that lack ma...
Lysergic Acid Diethylamide - Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic syste...
Mescaline - Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhaloniu...
Metergoline - A dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopami...
Methylergonovine - A homolog of ERGONOVINE containing one more CH2 group. (Merck Index, 11th ed)...
Methysergide - An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of...
Monocrotaline - A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the...
Morphinans - Compounds based on a partially saturated iminoethanophenanthrene, which can be described as ethylimi...
Morphine - The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widesp...
Morphine Derivatives - Analogs or derivatives of morphine....
Muscarine - A toxic alkaloid found in Amanita muscaria (fly fungus) and other fungi of the Inocybe species. It i...
Nalbuphine - A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an a...
Nalorphine - A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and a...
Naloxone - A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, del...
Naltrexone - Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic ...
Nicergoline - An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease....
Nicotine - Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors...
N-Methylscopolamine - A muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors....
Noscapine - A naturally occurring opium alkaloid that is a centrally acting antitussive agent....
Opiate Alkaloids - Alkaloids found in OPIUM from PAPAVER that induce analgesic and narcotic effects by action upon OPIO...
Oxycodone - Semisynthetic derivative of CODEINE that acts as a narcotic analgesic more potent and addicting than...
Oxymorphone - An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cou...
Papaverine - An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or ...
Papaverine - An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or ...
Pentazocine - The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma...
Pergolide - A long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA...
Phenazocine - An opioid analgesic with actions and uses similar to MORPHINE. (From Martindale, The Extra Pharmacop...
Physostigmine - A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically t...
Pilocarpine - A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic an...
Prajmaline - A derivative of the rauwolfia alkaloid AJMALINE. It is an anti-arrhythmia agent, but may cause liver...
Protoveratrines - Mixtures of closely related hypotensive alkaloids from Veratrum album (Liliaceae). They have been us...
Psilocybine - The major of two hallucinogenic components of Teonanacatl, the sacred mushroom of Mexico, the other ...
Pyrrolizidine Alkaloids - A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of t...
Quinidine - An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species...
Quinine - An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is t...
Reserpine - An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the upta...
Ryanodine - A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL...
Salsoline Alkaloids - Tetrahydroisoquinolinol alkaloids in both dextro and levo forms, originally found in SALSOLA plants....
Scopolamine - An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivati...
Scopolamine - An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivati...
Scopolamine Derivatives - Analogs or derivatives of scopolamine....
Secologanin Tryptamine Alkaloids - Compounds formed by condensation of secologanin with tryptamine resulting in a tetrahydro-beta-carbo...
Solanaceous Alkaloids - Alkaloids, mainly tropanes, elaborated by plants of the family Solanaceae, including Atropa, Hyoscya...
Solanine - A mixture of alpha-chaconine and alpha-solanine, found in SOLANACEAE plants....
Sparteine - A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It...
Staurosporine - An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated response...
Strychnine - An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine re...
Swainsonine - An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhib...
Tetrahydropapaveroline - A leukomaine (animal alkaloid) formed in brain and liver from dopamine and L-dopa; it may be implica...
Tetrahydropapaveroline - A leukomaine (animal alkaloid) formed in brain and liver from dopamine and L-dopa; it may be implica...
Thebaine - A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It...
Theobromine - 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A...
Theophylline - A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, car...
Tomatine - An alkaloid that occurs in the extract of leaves of wild tomato plants. It has been found to inhibit...
Topotecan - An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYP...
Toxiferine - A curare alkaloid that is a very potent competitive nicotinic antagonist at the neuromuscular juncti...
Tropanes - N-methyl-8-azabicyclo[3.2.1]octanes best known for the ones found in PLANTS....
Tubocurarine - A neuromuscular blocker and active ingredient in CURARE; plant based alkaloid of Menispermaceae....
Uric Acid - An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is t...
Veratridine - A benzoate-cevane found in VERATRUM and Schoenocaulon. It activates SODIUM CHANNELS to stay open lon...
Veratrum Alkaloids - Alkaloids with powerful hypotensive effects isolated from American or European Hellebore (Veratrum v...
Vinblastine - Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)...
Vinca Alkaloids - A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They ...
Vincamine - A major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator a...
Vincristine - Antitumor alkaloid isolated from Vinca Rosea. (Merck, 11th ed.)...
Vindesine - Vinblastine derivative with antineoplastic activity against CANCER. Major side effects are myelosupp...
Xanthine - A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is...
Xanthines - Purine bases found in body tissues and fluids and in some plants....
Yohimbine - A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic a...
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
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Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
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Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.