Transferases
Categorical breakdown of terms falling inder the category of Transferases. Sub categories will become more specific in nature to the terms listed for Transferases.
Sub-Categories
Terms
1,4-alpha-Glucan Branching Enzyme - In glycogen or amylopectin synthesis, the enzyme that catalyzes the transfer of a segment of a 1,4-a...
1-Acylglycerol-3-Phosphate O-Acyltransferase - An enzyme that catalyzes the acyl group transfer of ACYL COA to 1-acyl-sn-glycerol 3-phosphate to ge...
1-Acylglycerophosphocholine O-Acyltransferase - An enzyme localized predominantly within the plasma membrane of lymphocytes. It catalyzes the transf...
1-Phosphatidylinositol 3-Kinase - An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate....
1-Phosphatidylinositol 4-Kinase - An enzyme that catalyzes the conversion of phosphatidylinositol (PHOSPHATIDYLINOSITOLS) to phosphati...
2',5'-Oligoadenylate Synthetase - An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and p...
2-Aminoadipate Transaminase - A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of amino group of L-2-aminoadipa...
2-Isopropylmalate Synthase - An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl ma...
3-Deoxy-7-Phosphoheptulonate Synthase - An enzyme that catalyzes the formation of 7-phospho-2-keto-3-deoxy-D-arabinoheptonate from phosphoen...
3-Oxoacyl-(Acyl-Carrier-Protein) Synthase - An enzyme of long-chain fatty acid synthesis, that adds a two-carbon unit from malonyl-(acyl carrier...
3-Phosphoshikimate 1-Carboxyvinyltransferase - An enzyme of the shikimate pathway of AROMATIC AMINO ACID biosynthesis, it generates 5-enolpyruvylsh...
4-Aminobutyrate Transaminase - An enzyme that converts brain gamma-aminobutyric acid (GAMMA-AMINOBUTYRIC ACID) into succinate semia...
5-Aminolevulinate Synthetase - An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl c...
5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase - An enzyme that catalyzes the formation of methionine by transfer of a methyl group from 5-methyltetr...
Acetate Kinase - An enzyme that catalyzes reversibly the phosphorylation of acetate in the presence of a divalent cat...
Acetolactate Synthase - A flavoprotein enzyme that catalyzes the formation of acetolactate from 2 moles of PYRUVATE in the b...
Acetyl-CoA C-Acetyltransferase - An enzyme that catalyzes the formation of acetoacetyl-CoA from two molecules of ACETYL COA. Some enz...
Acetyl-CoA C-Acyltransferase - Enzyme that catalyzes the final step of fatty acid oxidation in which ACETYL COA is released and the...
Acetylserotonin O-Methyltransferase - An enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to N-acetylseroton...
Acetyltransferases - Enzymes catalyzing the transfer of an acetyl group, usually from acetyl coenzyme A, to another compo...
Activin Receptors - Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREON...
Activin Receptors, Type I - One of the two types of ACTIVIN RECEPTORS or activin receptor-like kinases (ALK'S). There are severa...
Activin Receptors, Type II - One of the two types of ACTIVIN RECEPTORS. They are membrane protein kinases belonging to the family...
Acyl-Carrier Protein S-Acetyltransferase - A enzyme that catalyzes the transfer of acetyl groups from ACETYL CoA to acyl-carrier protein to for...
Acyl-Carrier Protein S-Malonyltransferase - This enzyme catalyzes the transacylation of malonate from MALONYL CoA to activated holo-ACP, to gene...
Acyltransferases - Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor,...
Adenine Phosphoribosyltransferase - An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act a...
Adenosine Kinase - An enzyme that catalyzes the formation of ADP plus AMP from adenosine plus ATP. It can serve as a sa...
Adenylate Kinase - An enzyme that catalyzes the phosphorylation of AMP to ADP in the presence of ATP or inorganic triph...
ADP Ribose Transferases - Enzymes that transfer the ADP-RIBOSE group of NAD or NADP to proteins or other small molecules. Tran...
ADP-ribosyl Cyclase - A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from ...
Alanine Transaminase - An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate....
Aldehyde-Ketone Transferases - Enzymes that catalyze the transfer of aldehyde or ketone residues. EC 2.2....
Alkyl and Aryl Transferases - A somewhat heterogeneous class of enzymes that catalyze the transfer of alkyl or related groups (exc...
Amidinotransferases - Enzymes of a subclass of TRANSFERASES that catalyze the transfer of an amidino group from donor to a...
Amidophosphoribosyltransferase - An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyzes the formati...
Amino-Acid N-Acetyltransferase - A mitochondrial matrix enzyme that catalyzes the synthesis of L-GLUTAMATE to N-acetyl-L-glutamate in...
Aminoacyltransferases - Enzymes that catalyze the transfer of an aminoacyl group from donor to acceptor resulting in the for...
Aminomethyltransferase - A one-carbon group transferase that transfers lipoamide-linked methylamine groups to tetrahydrofolat...
AMP-Activated Protein Kinases - Intracellular signaling protein kinases that play a signaling role in the regulation of cellular ene...
Anthranilate Phosphoribosyltransferase - An enzyme that catalyzes the formation of N-5'-phosphoribosylanthranilic acid from anthranilate and ...
Arginine Kinase - An enzyme that catalyzes the phosphorylation of the guanidine nitrogen of arginine in the presence o...
Arylalkylamine N-Acetyltransferase - An acetyltransferase with specificity towards the amine group of aromatic alkylamines (arylalkylamin...
Arylamine N-Acetyltransferase - An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also ca...
Arylsulfotransferase - A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsul...
Aspartate Aminotransferase, Cytoplasmic - An aspartate aminotransferase found in the CYTOPLASM....
Aspartate Aminotransferase, Mitochondrial - An aspartate aminotransferase found in MITOCHONDRIA....
Aspartate Aminotransferases - Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to ...
Aspartate Carbamoyltransferase - An enzyme that catalyzes the conversion of carbamoyl phosphate and L-aspartate to yield orthophospha...
Aspartate Kinase - An enzyme that catalyzes the formation of beta-aspartyl phosphate from aspartic acid and ATP. Threon...
Aspartokinase Homoserine Dehydrogenase - An enzyme complex consisting of aspartokinase, EC 2.7.2.4, and homoserine dehydrogenase, EC 1.1.1.3....
ATP Citrate (pro-S)-Lyase - An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield ac...
ATP Phosphoribosyltransferase - An enzyme that catalyzes the first step of the pathway for histidine biosynthesis in Salmonella typh...
ATP Synthetase Complexes - Multisubunit enzyme complexes that synthesize ADENOSINE TRIPHOSPHATE from energy sources such as ion...
Bacterial Proton-Translocating ATPases - Membrane-bound proton-translocating ATPases that serve two important physiological functions in bact...
beta-Adrenergic Receptor Kinases - G-protein-coupled receptor kinases that mediate agonist-dependent PHOSPHORYLATION and desensitizatio...
beta-Alanine-Pyruvate Transaminase - A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of an amino group from L-ALANINE...
Betaine-Homocysteine S-Methyltransferase - A ZINC metalloenzyme that catalyzes the transfer of a methyl group from BETAINE to HOMOCYSTEINE to p...
beta-N-Acetylglucosaminylglycopeptide beta-1,4-Galactosyltransferase - An enzyme that catalyzes the transfer of galactose from UDP-galactose to a specific glycoprotein rec...
Bone Morphogenetic Protein Receptors - A family of CELL SURFACE RECEPTORS that bind BONE MORPHOGENETIC PROTEINS. They are PROTEIN-SERINE-TH...
Bone Morphogenetic Protein Receptors, Type I - A subtype of bone morphogenetic protein receptors with high affinity for BONE MORPHOGENETIC PROTEINS...
Bone Morphogenetic Protein Receptors, Type II - A subtype of bone morphogenetic protein receptors with low affinity for BONE MORPHOGENETIC PROTEINS....
Calcium-Calmodulin-Dependent Protein Kinase Kinase - A regulatory calcium-calmodulin-dependent protein kinase that specifically phosphorylates CALCIUM-CA...
Calcium-Calmodulin-Dependent Protein Kinase Type 1 - A monomeric calcium-calmodulin-dependent protein kinase subtype that is expressed in a broad variety...
Calcium-Calmodulin-Dependent Protein Kinase Type 2 - A multifunctional calcium-calmodulin-dependent protein kinase subtype that occurs as an oligomeric p...
Calcium-Calmodulin-Dependent Protein Kinase Type 4 - A monomeric calcium-calmodulin-dependent protein kinase subtype that is primarily expressed in neuro...
Calcium-Calmodulin-Dependent Protein Kinases - A CALMODULIN-dependent enzyme that catalyzes the phosphorylation of proteins. This enzyme is also so...
Carboxyl and Carbamoyl Transferases - A group of enzymes that catalyze the transfer of carboxyl- or carbamoyl- groups. EC 2.1.3....
Carnitine Acyltransferases - Acyltransferases in the inner mitochondrial membrane that catalyze the reversible transfer of acyl g...
Carnitine O-Acetyltransferase - An enzyme that catalyzes the formation of O-acetylcarnitine from acetyl-CoA plus carnitine. EC 2.3.1...
Carnitine O-Acetyltransferase - An enzyme that catalyzes the formation of O-acetylcarnitine from acetyl-CoA plus carnitine. EC 2.3.1...
Carnitine O-Palmitoyltransferase - An enzyme that catalyzes reversibly the conversion of palmitoyl-CoA to palmitoylcarnitine in the inn...
Casein Kinase I - A casein kinase that was originally described as a monomeric enzyme with a molecular weight of 30-40...
Casein Kinase Ialpha - A casein kinase I isoenzyme that plays a role in intracellular signaling pathways including the CELL...
Casein Kinase Idelta - A casein kinase I isoenzyme that plays a regulatory role in a variety of cellular functions includin...
Casein Kinase Iepsilon - A casein kinase I isoenzyme with specificity for proteins involved the regulation of the CIRCADIAN R...
Casein Kinase II - A ubiquitous casein kinase that is comprised of two distinct catalytic subunits and dimeric regulato...
Casein Kinases - A group of protein-serine-threonine kinases that was originally identified as being responsible for ...
Catechol O-Methyltransferase - Enzyme that catalyzes the movement of a methyl group from S-adenosylmethionone to a catechol or a ca...
CDC2 Protein Kinase - Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL ...
CDC2 Protein Kinase - Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL ...
CDC28 Protein Kinase, S cerevisiae - A protein kinase encoded by the Saccharomyces cerevisiae CDC28 gene and required for progression fro...
CDC2-CDC28 Kinases - A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE; S CE...
CDC2-CDC28 Kinases - A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE; S CE...
CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase - An enzyme that catalyzes the formation of PHOSPHATIDYLINOSITOL and CMP from CDP-DIACYLGLYCEROL and M...
CDPdiacylglycerol-Serine O-Phosphatidyltransferase - An enzyme that catalyzes the formation of phosphatidylserine and CMP from CDPdiglyceride plus serine...
Chitin Synthase - An enzyme that converts UDP glucosamine into chitin and UDP. EC 2.4.1.16....
Chloramphenicol O-Acetyltransferase - An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Sinc...
Chloroplast Proton-Translocating ATPases - Proton-translocating ATPases which produce ADENOSINE TRIPHOSPHATE in plants. They derive energy from...
Cholera Toxin - An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit ...
Choline Kinase - An enzyme that is active in the first step of choline phosphoglyceride (lecithin) biosynthesis by ca...
Choline O-Acetyltransferase - An enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline. EC 2.3.1.6....
Choline-Phosphate Cytidylyltransferase - An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. I...
Citrate (si)-Synthase - Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyz...
CLOCK Proteins - Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSF...
Coenzyme A-Transferases - Enzymes which transfer coenzyme A moieties from acyl- or acetyl-CoA to various carboxylic acceptors ...
Creatine Kinase - A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores A...
Creatine Kinase, BB Form - A form of creatine kinase found in the BRAIN....
Creatine Kinase, MB Form - An isoenzyme of creatine kinase found in the CARDIAC MUSCLE....
Creatine Kinase, Mitochondrial Form - A form of creatine kinase found in the MITOCHONDRIA....
Creatine Kinase, MM Form - An isoenzyme of creatine kinase found in the MUSCLE....
CREB-Binding Protein - A member of the p300-CBP transcription factor family that was initially identified as a binding part...
Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - Specific enzyme subunits that form the active sites of the type I and type II cyclic-AMP protein kin...
Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - Specific enzyme subunits that form the active sites of the type I and type II cyclic-AMP protein kin...
Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - A type I cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP ...
Cyclic AMP-Dependent Protein Kinase RIbeta Subunit - A type I cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP ...
Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit - A type II cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP...
Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - A type II cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP...
Cyclic AMP-Dependent Protein Kinase Type I - A cyclic AMP-dependent protein kinase subtype primarily found in the CYTOPLASM. They are tetrameric ...
Cyclic AMP-Dependent Protein Kinase Type II - A cyclic AMP-dependent protein kinase subtype primarily found in particulate subcellular fractions. ...
Cyclic AMP-Dependent Protein Kinases - A group of enzymes that are dependent on CYCLIC AMP and catalyze the phosphorylation of SERINE or TH...
Cyclic GMP-Dependent Protein Kinases - A group of enzymes that are dependent on cyclic GMP and catalyzes the phosphorylation of serine or t...
Cyclic Nucleotide-Regulated Protein Kinases - A group of enzymes that catalyzes the phosphorylation of serine or threonine residues of proteins an...
Cyclin-Dependent Kinase 2 - A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE ...
Cyclin-Dependent Kinase 2 - A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE ...
Cyclin-Dependent Kinase 3 - A cyclin-dependent kinase that forms a complex with CYCLIN C and is active during the G1 PHASE of th...
Cyclin-Dependent Kinase 3 - A cyclin-dependent kinase that forms a complex with CYCLIN C and is active during the G1 PHASE of th...
Cyclin-Dependent Kinase 4 - Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN ...
Cyclin-Dependent Kinase 4 - Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN ...
Cyclin-Dependent Kinase 5 - A serine-threonine kinase that plays important roles in CELL DIFFERENTIATION; CELL MIGRATION; and CE...
Cyclin-Dependent Kinase 5 - A serine-threonine kinase that plays important roles in CELL DIFFERENTIATION; CELL MIGRATION; and CE...
Cyclin-Dependent Kinase 6 - Cyclin-dependent kinase 6 associates with CYCLIN D and phosphorylates RETINOBLASTOMA PROTEIN during ...
Cyclin-Dependent Kinase 6 - Cyclin-dependent kinase 6 associates with CYCLIN D and phosphorylates RETINOBLASTOMA PROTEIN during ...
Cyclin-Dependent Kinase 8 - A CYCLIN C dependent kinase that is an important component of the mediator complex. The enzyme is ac...
Cyclin-Dependent Kinase 9 - A multifunctional CDC2 kinase-related kinase that plays roles in transcriptional elongation, CELL DI...
Cyclin-Dependent Kinases - Protein kinases that control cell cycle progression in all eukaryotes and require physical associati...
Cyclin-Dependent Kinases - Protein kinases that control cell cycle progression in all eukaryotes and require physical associati...
Cysteine Synthase - An enzyme that catalyzes the biosynthesis of cysteine in microorganisms and plants from O-acetyl-L-s...
D-Alanine Transaminase - A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the reversible transfer of an amino group bet...
DEAD Box Protein 20 - A multifunctional protein that is both a DEAD-box RNA helicase and a component of the SMN protein c...
DEAD-box RNA Helicases - A large family of RNA helicases that share a common protein motif with the single letter amino acid ...
Deoxycytidine Kinase - An enzyme that catalyzes reversibly the phosphorylation of deoxycytidine with the formation of a nuc...
Diacylglycerol Cholinephosphotransferase - An enzyme that catalyzes the synthesis of phosphatidylcholines from CDPcholine and 1,2-diacylglycero...
Diacylglycerol Kinase - An enzyme of the transferase class that uses ATP to catalyze the phosphorylation of diacylglycerol t...
Diacylglycerol O-Acyltransferase - An enzyme that catalyses the last step of the TRIACYLGLYCEROL synthesis reaction in which diacylglyc...
Dihydrolipoyllysine-Residue Acetyltransferase - An enzyme that catalyzes the acetyltransferase reaction using ACETYL CoA as an acetyl donor and dihy...
Dihydropteroate Synthase - An enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropterid...
Dimethylallyltranstransferase - An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopenteny...
Diphosphotransferases - A class of phosphotransferases that catalyzes the transfer of diphosphate-containing groups. EC 2.7....
Diphtheria Toxin - An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and sy...
DNA (Cytosine-5-)-Methyltransferase - An enzyme that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the 5-position ...
DNA Modification Methylases - Enzymes that are part of the restriction-modification systems. They are responsible for producing a ...
DNA Nucleotidylexotransferase - A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catal...
DNA Nucleotidyltransferases - Enzymes that catalyze the incorporation of deoxyribonucleotides into a chain of DNA. EC 2.7.7.-....
DNA Polymerase beta - A DNA repair enzyme that catalyzes DNA synthesis during base excision DNA repair. EC 2.7.7.7....
DNA Polymerase I - A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. ...
DNA Polymerase II - A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present...
DNA Polymerase III - A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present...
DNA Primase - A single-stranded DNA-dependent RNA polymerase that functions to initiate, or prime, DNA synthesis b...
DNA, Catalytic - Molecules of DNA that possess enzymatic activity....
DNA-Activated Protein Kinase - A serine-threonine protein kinase that, when activated by DNA, phosphorylates several DNA-binding pr...
DNA-Cytosine Methylases - Methylases that are specific for CYTOSINE residues found on DNA....
DNA-Directed DNA Polymerase - DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication proc...
DNA-Directed RNA Polymerases - Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide ...
E1A-Associated p300 Protein - A member of the p300-CBP transcription factors that was originally identified as a binding partner f...
eIF-2 Kinase - A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In...
Elongation Factor 2 Kinase - A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEP...
Ethanolaminephosphotransferase - An enzyme that catalyzes reversibly the transfer of phosphoethanolamine from CDP-ethanolamine to dia...
Eukaryotic Initiation Factor-4A - A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the sec...
Extracellular Signal-Regulated MAP Kinases - A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation...
Extracellular Signal-Regulated MAP Kinases - A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation...
Factor XIIIa - Activated form of FACTOR XIII, a transglutaminase, which stabilizes the formation of the fibrin poly...
Farnesyl-Diphosphate Farnesyltransferase - The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it c...
Farnesyltranstransferase - An enzyme that catalyzes the synthesis of geranylgeranyl diphosphate from trans, trans-farnesyl diph...
fms-Like Tyrosine Kinase 3 - A receptor tyrosine kinase that is involved in HEMATOPOIESIS. It is closely related to FMS PROTO-ONC...
Focal Adhesion Kinase 1 - A non-receptor protein tyrosine kinase that is localized to FOCAL ADHESIONS and is a central compone...
Focal Adhesion Kinase 2 - A non-receptor protein-tyrosine kinase that is expressed primarily in the BRAIN; OSTEOBLASTS; and LY...
Focal Adhesion Protein-Tyrosine Kinases - A family of non-receptor, PROLINE-rich protein-tyrosine kinases....
Fructokinases - A class of enzymes that catalyzes the phosphorylation of fructose in the presence of ATP. EC 2.7.1.-...
Fucosyl Galactose alpha-N-Acetylgalactosaminyltransferase - An enzyme that catalyzes the transfer of acetylgalactosamine from UDP N-acetylgalactosamine to vario...
Fucosyltransferases - Enzymes catalyzing the transfer of fucose from a nucleoside diphosphate fucose to an acceptor molecu...
Fusion Proteins, bcr-abl - Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the g...
Galactokinase - An enzyme that catalyzes reversibly the formation of galactose 1-phosphate and ADP from ATP and D-ga...
Galactosyltransferases - Enzymes that catalyze the transfer of galactose from a nucleoside diphosphate galactose to an accept...
gamma-Glutamylcyclotransferase - An enzyme that catalyzes the synthesis of pyroglutamate from a gamma-glutamyl-amino acid, also relea...
gamma-Glutamyltransferase - An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (G...
Ganglioside Galactosyltransferase - Catalyzes the final step in the galactocerebroside biosynthesis pathway....
Geranylgeranyl-Diphosphate Geranylgeranyltransferase - An enzyme that catalyzes the condensation of two molecules of geranylgeranyl diphosphate to give pre...
Geranyltranstransferase - An enzyme involved in the MEVALONATE pathway, it catalyses the synthesis of farnesyl diphosphate fro...
Glucokinase - A group of enzymes that catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phospha...
Glucosamine 6-Phosphate N-Acetyltransferase - An enzyme that catalyses the reaction of D-glucosamine 6-phosphate with ACETYL-COA to form N-acetylg...
Glucose-1-Phosphate Adenylyltransferase - An ATP-dependent enzyme that catalyzes the addition of ADP to alpha-D-glucose 1-phosphate to form AD...
Glucosyltransferases - Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor m...
Glucuronosyltransferase - A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and f...
Glutamate Formimidoyltransferase - A PYRIDOXAL PHOSPHATE-containing enzyme that catalyzes the transfer of a formyl group from L-GLUTAMA...
Glutamate Synthase - An enzyme that catalyzes the formation of 2 molecules of glutamate from glutamine plus alpha-ketoglu...
Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) - An enzyme that catalyzes the synthesis of fructose-6-phosphate plus GLUTAMINE from GLUTAMATE plus gl...
Glutathione S-Transferase pi - A glutathione transferase that catalyzes the conjugation of electrophilic substrates to GLUTATHIONE....
Glutathione Transferase - A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as w...
Glycerol Kinase - An enzyme that catalyzes the formation of glycerol 3-phosphate from ATP and glycerol. Dihydroxyaceto...
Glycerol-3-Phosphate O-Acyltransferase - An enzyme that transfers acyl groups from acyl-CoA to glycerol-3-phosphate to form monoglyceride pho...
Glycine Hydroxymethyltransferase - A pyridoxal phosphate enzyme that catalyzes the reaction of glycine and 5,10-methylene-tetrahydrofol...
Glycine N-Methyltransferase - An enzyme that catalyzes the METHYLATION of GLYCINE using S-ADENOSYLMETHIONINE to form SARCOSINE wit...
Glycine Transaminase - A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of amino group of GLYCINE onto 2...
Glycogen Debranching Enzyme System - 1,4-alpha-D-Glucan-1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase/dextrin 6 alpha-D-glucanohydrola...
Glycogen Phosphorylase - An enzyme that catalyzes the degradation of GLYCOGEN in animals by releasing glucose-1-phosphate fro...
Glycogen Phosphorylase, Brain Form - An isoenzyme of GLYCOGEN PHOSPHORYLASE that catalyzes the degradation of GLYCOGEN in brain tissue....
Glycogen Phosphorylase, Liver Form - An isoenzyme of GLYCOGEN PHOSPHORYLASE that catalyzes the degradation of GLYCOGEN in liver tissue. M...
Glycogen Phosphorylase, Muscle Form - An isoenzyme of GLYCOGEN PHOSPHORYLASE that catalyzes the degradation of GLYCOGEN in muscle. Mutatio...
Glycogen Synthase - An enzyme that catalyzes the transfer of D-glucose from UDPglucose into 1,4-alpha-D-glucosyl chains....
Glycogen Synthase Kinase 3 - A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabo...
Glycogen Synthase Kinase 3 - A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabo...
Glycogen Synthase Kinases - A class of protein-serine-threonine kinases that was originally found as one of the three types of k...
Glycosyltransferases - Enzymes that catalyze the transfer of glycosyl groups to an acceptor. Most often another carbohydrat...
G-Protein-Coupled Receptor Kinase 1 - A PROTEIN-SERINE-THREONINE KINASE that is found in PHOTORECEPTOR CELLS. It mediates light-dependent ...
G-Protein-Coupled Receptor Kinase 2 - A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agon...
G-Protein-Coupled Receptor Kinase 3 - A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agon...
G-Protein-Coupled Receptor Kinase 4 - A G-protein-coupled receptor kinase subtype that is primarily expressed in the TESTES and BRAIN. Var...
G-Protein-Coupled Receptor Kinase 5 - A G-protein-coupled receptor kinase subtype that is primarily expressed in the MYOCARDIUM and may pl...
G-Protein-Coupled Receptor Kinases - A family of serine-threonine kinases that are specific for G-PROTEIN-COUPLED RECEPTORS. They are reg...
GTP Pyrophosphokinase - An enzyme that catalyzes reversibly the transfer of a pyrophosphate group from ATP to the 3'-OH grou...
Guanidinoacetate N-Methyltransferase - This enzyme catalyzes the last step of CREATINE biosynthesis by catalyzing the METHYLATION of guanid...
Guanylate Kinase - Catalyzes the ATP-dependent PHOSPHORYLATION of GMP to generate GDP and ADP....
Hexokinase - An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-G...
Hexosyltransferases - Enzymes that catalyze the transfer of hexose groups. EC 2.4.1.-....
Histamine N-Methyltransferase - An enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to histamine, form...
Histone Acetyltransferases - Enzymes that catalyze acyl group transfer from ACETYL-CoA to HISTONES forming CoA and acetyl-histone...
Histone-Lysine N-Methyltransferase - An enzyme that catalyzes the methylation of the epsilon-amino group of lysine residues in proteins t...
HIV Integrase - Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA...
HIV Reverse Transcriptase - A reverse transcriptase encoded by the POL GENE of HIV. It is a heterodimer of 66 kDa and 51 kDa sub...
Homocysteine S-Methyltransferase - An enzyme that catalyzes the demethylation of L-homocysteine to L-METHIONINE....
Homoserine O-Succinyltransferase - The first enzyme in the METHIONINE biosynthetic pathway, this enzyme catalyzes the succinylation rea...
Hydroxymethyl and Formyl Transferases - Enzymes that catalyze the transfer of hydroxymethyl or formyl groups. EC 2.1.2....
Hydroxymethylbilane Synthase - An enzyme that catalyzes the tetrapolymerization of the monopyrrole PORPHOBILINOGEN into the hydroxy...
Hydroxymethylglutaryl-CoA Synthase - An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-...
Hypoxanthine Phosphoribosyltransferase - An enzyme that catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanin...
I-kappa B Kinase - A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enz...
Interleukin-1 Receptor-Associated Kinases - A family of intracellular signaling kinases that were identified by their ability to signal from the...
Janus Kinase 1 - A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS....
Janus Kinase 2 - A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPT...
Janus Kinase 3 - A Janus kinase subtype that is predominantly expressed in hematopoietic cell. It is involved in sign...
Janus Kinases - A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by...
JNK Mitogen-Activated Protein Kinases - A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phos...
JNK Mitogen-Activated Protein Kinases - A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phos...
Kanamycin Kinase - A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by reg...
Lactose Synthase - An enzyme of the transferase class that catalyzes the transfer of galactose from UDPgalactose to glu...
Leucine Transaminase - A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the reversible transamination of branched-cha...
Lim Kinases - Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembl...
L-Lysine 6-Transaminase - A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of amino group of L-LYSINE onto ...
Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell developmen...
Malate Synthase - An important enzyme in the glyoxylic acid cycle which reversibly catalyzes the synthesis of L-malate...
Mannosyltransferases - Enzymes that catalyze the transfer of mannose from a nucleoside diphosphate mannose to an acceptor m...
MAP Kinase Kinase 1 - An abundant 43-kDa mitogen-activated protein kinase kinase subtype with specificity for MITOGEN-ACTI...
MAP Kinase Kinase 1 - An abundant 43-kDa mitogen-activated protein kinase kinase subtype with specificity for MITOGEN-ACTI...
MAP Kinase Kinase 2 - A 44 kDa mitogen-activated protein kinase kinase with specificity for MITOGEN-ACTIVATED PROTEIN KINA...
MAP Kinase Kinase 2 - A 44 kDa mitogen-activated protein kinase kinase with specificity for MITOGEN-ACTIVATED PROTEIN KINA...
MAP Kinase Kinase 3 - A mitogen-activated protein kinase kinase with specificity for a subset of P38 MITOGEN-ACTIVATED PR...
MAP Kinase Kinase 3 - A mitogen-activated protein kinase kinase with specificity for a subset of P38 MITOGEN-ACTIVATED PR...
MAP Kinase Kinase 4 - A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES...
MAP Kinase Kinase 4 - A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES...
MAP Kinase Kinase 5 - A mitogen-activated protein kinase kinase with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 7....
MAP Kinase Kinase 5 - A mitogen-activated protein kinase kinase with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 7....
MAP Kinase Kinase 6 - A mitogen-activated protein kinase kinase with specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES...
MAP Kinase Kinase 6 - A mitogen-activated protein kinase kinase with specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES...
MAP Kinase Kinase 7 - A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES...
MAP Kinase Kinase 7 - A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES...
MAP Kinase Kinase Kinase 1 - A 195-kDa MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It is found locali...
MAP Kinase Kinase Kinase 2 - A 70-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 5. It is activated during t...
MAP Kinase Kinase Kinase 3 - A 70-kDa MAPK kinase kinase with specificity for MAP KINASE KINASE 5....
MAP Kinase Kinase Kinase 4 - A 180-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 4 and MAP KINASE KINASE 6....
MAP Kinase Kinase Kinase 5 - A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specif...
MAP Kinase Kinase Kinases - Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that ...
Maturation-Promoting Factor - Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meios...
Methionine Adenosyltransferase - An enzyme that catalyzes the synthesis of S-adenosylmethionine from methionine and ATP. EC 2.5.1.6....
Methyltransferases - A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one...
Mitochondrial Proton-Translocating ATPases - Proton-translocating ATPases responsible for ADENOSINE TRIPHOSPHATE synthesis in the MITOCHONDRIA. T...
Mitogen-Activated Protein Kinase 1 - A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell ...
Mitogen-Activated Protein Kinase 1 - A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell ...
Mitogen-Activated Protein Kinase 10 - A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a ...
Mitogen-Activated Protein Kinase 10 - A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a ...
Mitogen-Activated Protein Kinase 3 - A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulatio...
Mitogen-Activated Protein Kinase 3 - A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulatio...
Mitogen-Activated Protein Kinase 6 - A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increa...
Mitogen-Activated Protein Kinase 6 - A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increa...
Mitogen-Activated Protein Kinase 7 - A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress...
Mitogen-Activated Protein Kinase 7 - A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress...
Mitogen-Activated Protein Kinase 8 - A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokin...
Mitogen-Activated Protein Kinase 8 - A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokin...
Mitogen-Activated Protein Kinase 9 - A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokin...
Mitogen-Activated Protein Kinase 9 - A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokin...
Mitogen-Activated Protein Kinase Kinases - A serine-threonine protein kinase family whose members are components in protein kinase cascades act...
Mitogen-Activated Protein Kinase Kinases - A serine-threonine protein kinase family whose members are components in protein kinase cascades act...
Mitogen-Activated Protein Kinases - A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein ...
Mitogen-Activated Protein Kinases - A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein ...
Myosin Type III - A subclass of myosins originally found in the photoreceptor of DROSOPHILA. The heavy chains can occu...
Myosin-Light-Chain Kinase - An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain...
N-Acetylgalactosaminyltransferases - Enzymes that catalyze the transfer of N-acetylgalactosamine from a nucleoside diphosphate N-acetylga...
N-Acetylglucosaminyltransferases - Enzymes that catalyze the transfer of N-acetylglucosamine from a nucleoside diphosphate N-acetylgluc...
N-Acetylhexosaminyltransferases - Enzymes that catalyze the transfer of N-acetylhexosaminyl groups to an acceptor molecule which is fr...
N-Acetyllactosamine Synthase - The A protein of the lactose synthase complex. In the presence of the B protein (LACTALBUMIN) specif...
N-Acylneuraminate Cytidylyltransferase - An enzyme that forms CMP-acylneuraminic acids, which donate the N-acylneuraminic acid residues to th...
N-Acylsphingosine Galactosyltransferase - An enzyme that catalyzes the conversion of UDP-galactose and N-acylsphingosine to D-galactosylcerami...
NAD+ Nucleosidase - An enzyme that catalyzes the hydrolysis of nicotinamide adenine dinucleotide (NAD) to NICOTINAMIDE a...
Nicotinamide N-Methyltransferase - An enzyme found primarily in the LIVER that catalyzes the N-methylation of NICOTINAMIDE and other st...
Nicotinamide Phosphoribosyltransferase - An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-...
Nicotinamide-Nucleotide Adenylyltransferase - An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl gro...
Nitrogenous Group Transferases - Enzymes that catalyze the transfer of nitrogenous groups, primarily amino groups, from a donor, gene...
NM23 Nucleoside Diphosphate Kinases - A family of nucleotide diphosphate kinases that play a role in a variety of cellular signaling pathw...
Nuclear Receptor Coactivator 1 - A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and ...
Nuclear Receptor Coactivator 3 - A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE RECEPTORS. I...
Nucleoside-Diphosphate Kinase - An enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyzes reversib...
Nucleoside-Phosphate Kinase - An enzyme that catalyzes reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleo...
Nucleotidyltransferases - A class of enzymes that transfers nucleotidyl residues. EC 2.7.7....
O(6)-Methylguanine-DNA Methyltransferase - An enzyme that transfers methyl groups from O(6)-methylguanine, and other methylated moieties of DNA...
Oncogene Protein pp60(v-src) - A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transfor...
Oncogene Protein v-akt - A viral oncoprotein originally isolated from a murine T CELL LYMPHOMA infected with the acutely tran...
Oncogene Proteins v-raf - A family of transforming proteins isolated from retroviruses such as MOUSE SARCOMA VIRUSES. They are...
One-Carbon Group Transferases - A subclass of transferases that transfer chemical groups containing a single carbon. These include t...
Ornithine Carbamoyltransferase - A urea cycle enzyme that catalyzes the formation of orthophosphate and L-citrulline (CITRULLINE) fro...
Ornithine-Oxo-Acid Transaminase - A pyridoxal phosphate enzyme that catalyzes the formation of glutamate gamma-semialdehyde and an L-a...
Orotate Phosphoribosyltransferase - The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic ac...
p21-Activated Kinases - A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEIN...
p300-CBP Transcription Factors - A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E...
p38 Mitogen-Activated Protein Kinases - A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes includin...
p38 Mitogen-Activated Protein Kinases - A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes includin...
Pentosyltransferases - Enzymes of the transferase class that catalyze the transfer of a pentose group from one compound to ...
Peptidoglycan Glycosyltransferase - A hexosyltransferase involved in the transfer of disaccharide molecules to the peptidoglycan structu...
Peptidyl Transferases - Acyltransferases that use AMINO ACYL TRNA as the amino acid donor in formation of a peptide bond. Th...
Pertussis Toxin - One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed o...
Phenylethanolamine N-Methyltransferase - A methyltransferase that catalyzes the reaction of S-adenosyl-L-methionine and phenylethanolamine to...
Phosphate Acetyltransferase - An enzyme that catalyzes the synthesis of acetylphosphate from acetyl-CoA and inorganic phosphate. A...
Phosphatidylcholine-Sterol O-Acyltransferase - An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esteri...
Phosphatidylethanolamine N-Methyltransferase - An enzyme that catalyses three sequential METHYLATION reactions for conversion of phosphatidylethano...
Phosphatidyl-N-Methylethanolamine N-Methyltransferase - An enzyme that catalyzes the METHYLATION of phosphatidyl-N-methylethanolamine to produce phosphatidy...
Phosphoenolpyruvate Sugar Phosphotransferase System - The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl gr...
Phosphofructokinase-1 - An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ...
Phosphofructokinase-1, Liver Type - An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ...
Phosphofructokinase-1, Muscle Type - An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ...
Phosphofructokinase-1, Type C - An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ...
Phosphofructokinase-2 - An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a p...
Phosphofructokinases - Allosteric enzymes that regulate glycolysis and gluconeogenesis. These enzymes catalyze phosphoryla...
Phosphoglycerate Kinase - An enzyme catalyzing the transfer of a phosphate group from 3-phospho-D-glycerate in the presence of...
Phosphoribosylaminoimidazolecarboxamide Formyltransferase - An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-a...
Phosphoribosylglycinamide Formyltransferase - An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-pho...
Phosphorylase a - The active form of GLYCOGEN PHOSPHORYLASE that is derived from the phosphorylation of PHOSPHORYLASE ...
Phosphorylase b - The inactive form of GLYCOGEN PHOSPHORYLASE that is converted to the active form PHOSPHORYLASE A via...
Phosphorylase Kinase - An enzyme that catalyzes the conversion of ATP and PHOSPHORYLASE B to ADP and PHOSPHORYLASE A....
Phosphorylases - A class of glucosyltransferases that catalyzes the degradation of storage polysaccharides, such as g...
Phosphotransferases - A rather large group of enzymes comprising not only those transferring phosphate but also diphosphat...
Phosphotransferases (Alcohol Group Acceptor) - A group of enzymes that transfers a phosphate group onto an alcohol group acceptor. EC 2.7.1....
Phosphotransferases (Carboxyl Group Acceptor) - A class of enzymes that transfers phosphate groups and has a carboxyl group as an acceptor. EC 2.7.2...
Phosphotransferases (Nitrogenous Group Acceptor) - A group of enzymes that catalyzes the transfer of a phosphate group onto a nitrogenous group accepto...
Phosphotransferases (Paired Acceptors) - A group of enzymes that transfers two phosphate groups from a donor such as ATP to two different acc...
Phosphotransferases (Phosphate Group Acceptor) - A group of enzymes that catalyzes the transfer of a phosphate group onto a phosphate group acceptor....
Phytochrome A - The primary plant photoreceptor responsible for perceiving and mediating responses to far-red light....
Poly(ADP-ribose) Polymerases - Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleot...
Polynucleotide 5'-Hydroxyl-Kinase - An enzyme that catalyzes the transfer of a phosphate group to the 5'-terminal hydroxyl groups of DNA...
Polynucleotide Adenylyltransferase - An enzyme that catalyzes the synthesis of polyadenylic acid from ATP. May be due to the action of RN...
Polyribonucleotide Nucleotidyltransferase - An enzyme of the transferase class that catalyzes the reaction RNA(n+1) and orthophosphate to yield ...
Positive Transcriptional Elongation Factor B - A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT K...
Proline-Directed Protein Kinases - A subclass of protein serine-threonine kinases that phosphorylate proteins on a SERINE or THREONINE ...
Protamine Kinase - An aspect of protein kinase (EC 2.7.1.37) in which serine residues in protamines and histones are ph...
Protein D-Aspartate-L-Isoaspartate Methyltransferase - A PROTEIN O-METHYLTRANSFERASE that recognizes and catalyzes the methyl esterification of ISOASPARTI...
Protein Kinase C - An serine-threonine protein kinase that requires the presence of physiological concentrations of CAL...
Protein Kinase C-alpha - A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLI...
Protein Kinase C-delta - A ubiquitously expressed protein kinase that is involved in a variety of cellular SIGNAL PATHWAYS. I...
Protein Kinase C-epsilon - A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threon...
Protein Kinases - A family of enzymes that catalyze the conversion of ATP and a protein to ADP and a phosphoprotein....
Protein Methyltransferases - Enzymes that catalyze the methylation of amino acids after their incorporation into a polypeptide ch...
Protein O-Methyltransferase - An enzyme that catalyzes the transfer of methyl groups from S-adenosylmethionine to free carboxyl gr...
Protein-Arginine N-Methyltransferases - Enzymes that catalyze the methylation of arginine residues of proteins to yield N-mono- and N,N-dime...
Protein-Serine-Threonine Kinases - A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, w...
Protein-Tyrosine Kinases - Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other...
Proton-Translocating ATPases - Multisubunit enzymes that reversibly synthesize ADENOSINE TRIPHOSPHATE. They are coupled to the tran...
Proto-Oncogene Proteins B-raf - A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kina...
Proto-Oncogene Proteins c-abl - Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm...
Proto-Oncogene Proteins c-akt - A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS...
Proto-Oncogene Proteins c-bcr - Proto-oncogene protein bcr is a serine-threonine kinase that functions as a negative regulator of CE...
Proto-Oncogene Proteins c-fes - Proto-oncogene proteins fes are protein-tyrosine kinases with a central SH2 DOMAIN. It has been impl...
Proto-Oncogene Proteins c-fyn - Src-family kinases that associate with T-CELL ANTIGEN RECEPTOR and phosphorylate a wide variety of i...
Proto-Oncogene Proteins c-hck - Members of the src-family tyrosine kinase family that are strongly expressed in MYELOID CELLS and B-...
Proto-Oncogene Proteins c-kit - A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucia...
Proto-Oncogene Proteins c-met - Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extr...
Proto-Oncogene Proteins c-mos - Cellular proteins encoded by the c-mos genes (GENES, MOS). They function in the cell cycle to mainta...
Proto-Oncogene Proteins c-pim-1 - Serine-threonine protein kinases that relay signals from CYTOKINE RECEPTORS and are involved in cont...
Proto-Oncogene Proteins c-raf - A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. T...
Proto-Oncogene Proteins c-ret - Receptor protein-tyrosine kinases involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC ...
Proto-Oncogene Proteins c-yes - Members of the src-family tyrosine kinases that are activated during the transition from G2 PHASE to...
Proto-Oncogene Proteins pp60(c-src) - Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important rol...
Purine-Nucleoside Phosphorylase - An enzyme that catalyzes the reaction between a purine nucleoside and orthophosphate to form a free ...
Pyridoxal Kinase - An enzyme that catalyzes reversibly the phosphorylation of pyridoxal in the presence of ATP with the...
Pyruvate Kinase - ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylat...
Pyruvate, Orthophosphate Dikinase - An enzyme that catalyzes the reaction of ATP, pyruvate, and orthophosphate to form AMP plus phosphoe...
Q beta Replicase - An enzyme that catalyzes the replication of the RNA of coliphage Q beta. EC 2.7.7.-....
raf Kinases - A family of closely-related serine-threonine kinases that were originally identified as the cellular...
Rec A Recombinases - A family of recombinases initially identified in BACTERIA. They catalyze the ATP-driven exchange of ...
Receptor Protein-Tyrosine Kinases - A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity....
Receptor Tyrosine Kinase-like Orphan Receptors - A family of cell surface receptors that were originally identified by their structural homology to n...
Receptor, EphA1 - The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producin...
Receptor, EphA2 - An Eph family receptor found abundantly in tissues of epithelial origin. It is expressed in a divers...
Receptor, EphA3 - An eph family receptor that is found primarily in adult BRAIN and variety of tissues in the developi...
Receptor, EphA4 - An eph family receptor found in variety of tissues including BRAIN. During embryogenesis, EphA4 rece...
Receptor, EphA5 - An eph family receptor found primarily in differentiated neuronal tissues. Several isoforms of EphA5...
Receptor, EphA6 - An eph family receptor that is found in a variety of neuronal regions of the BRAIN. In contrast to t...
Receptor, EphA7 - An eph family receptor found widely expressed in embryo tissues, including the NERVOUS SYSTEM. In th...
Receptor, EphA8 - An eph family receptor found exclusively in BRAIN. EphA8 receptors may play a role in the axonal gui...
Receptor, EphB1 - An eph family receptor found primarily in the nervous system. In the embryonic BRAIN EphB1 receptor ...
Receptor, EphB2 - An eph family receptor found widely expressed in embryonic and adult tissues. High levels of EphB2 r...
Receptor, EphB3 - An eph family receptor found in a number of tissues including BRAIN; LUNG; KIDNEY; PANCREAS; INTESTI...
Receptor, EphB4 - An eph family receptor found in a variety of adult and embryonic tissues. Unlike the majority of pro...
Receptor, EphB5 - An eph family receptor found at high levels in adult THYMUS and RETINA. In embryonic tissues it is f...
Receptor, Epidermal Growth Factor - A cell surface receptor involved in regulation of cell growth and differentiation. It is specific fo...
Receptor, erbB-2 - A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant n...
Receptor, erbB-3 - A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive h...
Receptor, Fibroblast Growth Factor, Type 1 - A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE ...
Receptor, Fibroblast Growth Factor, Type 2 - A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in ...
Receptor, Fibroblast Growth Factor, Type 3 - A fibroblast growth factor receptor that regulates CHONDROCYTE growth and CELL DIFFERENTIATION. Muta...
Receptor, Fibroblast Growth Factor, Type 4 - A fibroblast growth factor receptor that is mainly expressed in LUNG; KIDNEY; PANCREAS; and SPLEEN. ...
Receptor, IGF Type 1 - A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Alt...
Receptor, Insulin - A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits whic...
Receptor, Macrophage Colony-Stimulating Factor - A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS)...
Receptor, Platelet-Derived Growth Factor alpha - A PDGF receptor that binds specifically to both PDGF-A chains and PDGF-B chains. It contains a prote...
Receptor, Platelet-Derived Growth Factor beta - A PDGF receptor that binds specifically to the PDGF-B chain. It contains a protein-tyrosine kinase a...
Receptor, TIE-1 - A TIE receptor found predominantly on ENDOTHELIAL CELLS. It is considered essential for vascular dev...
Receptor, TIE-2 - A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required...
Receptor, trkA - A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotr...
Receptor, trkB - A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROP...
Receptor, trkC - A protein-tyrosine kinase receptor that is specific for NEUROTROPHIN 3. It is widely expressed in ne...
Receptor-Interacting Protein Serine-Threonine Kinase 2 - A RIP serine-theonine kinase that contains a C-terminal caspase activation and recruitment domain. I...
Receptor-Interacting Protein Serine-Threonine Kinases - A family of serine-threonine kinases that plays a role in intracellular signal transduction by inter...
Receptors, Eph Family - A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this ...
Receptors, Platelet-Derived Growth Factor - Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or...
Receptors, TIE - A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOT...
Receptors, Vascular Endothelial Growth Factor - A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth ...
Retinol O-Fatty-Acyltransferase - An enzyme that catalyzes the acyl group transfer of acyl COENZYME A to RETINOL to generate COENZYME ...
rho-Associated Kinases - A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. T...
Riboflavin Synthase - An enzyme that catalyzes the formation of riboflavin from two molecules of 6,7-dimethyl-8-ribityllum...
Ribose-Phosphate Pyrophosphokinase - An enzyme that catalyzes the formation of phosphoribosyl pyrophosphate from ATP and ribose-5-phospha...
Ribosomal Protein S6 Kinases - A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ri...
Ribosomal Protein S6 Kinases, 70-kDa - A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIB...
Ribosomal Protein S6 Kinases, 90-kDa - A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN ...
RNA Helicases - A family of proteins that promote unwinding of RNA during splicing and translation. EC 2.7.7.-....
RNA Nucleotidyltransferases - Enzymes that catalyze the template-directed incorporation of ribonucleotides into an RNA chain. EC 2...
RNA Polymerase I - A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions i...
RNA Polymerase II - A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nu...
RNA Polymerase III - A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nu...
RNA Polymerase Sigma 54 - A DNA-directed RNA polymerase found in BACTERIA. It is a holoenzyme that consists of multiple subuni...
RNA Replicase - An enzyme that catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucl...
RNA, Ribosomal, Self-Splicing - Components of ribosomal RNA that undergo auto-catalyzed molecular rearrangements of their RNA sequen...
RNA-Directed DNA Polymerase - An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and...
Serine C-Palmitoyltransferase - A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-depende...
Serine O-Acetyltransferase - An enzyme that catalyzes the conversion of L-SERINE to COENZYME A and O-acetyl-L-serine, using ACETY...
Sialyltransferases - A group of enzymes with the general formula CMP-N-acetylneuraminate:acceptor N-acetylneuraminyl tran...
Sirtuin 2 - A sirtuin family member found primarily in the CYTOPLASM. It is a multifunctional enzyme that contai...
Sirtuin 3 - A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contain...
Sirtuins - A homologous family of regulatory enzymes that are structurally related to the protein silent mating...
Site-Specific DNA-Methyltransferase (Adenine-Specific) - An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues...
Site-Specific DNA-Methyltransferase (Cytosine-N(4)-Specific) - A DNA-methyltransferase that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to t...
Spermidine Synthase - An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthioprop...
Spermine Synthase - An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthioprop...
Sphingosine N-Acyltransferase - An enzyme that catalyzes the acyltransferase of SPHINGOSINE to N-acylsphingosine using acyl-COENZYME...
src-Family Kinases - A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma viru...
Starch Phosphorylase - An enzyme of the PHOSPHORYLASES family that catalyzes the degradation of starch, a mixture of unbran...
Starch Synthase - An enzyme that catalyzes the transfer of glucose from ADPglucose to glucose-containing polysaccharid...
Sterol O-Acyltransferase - An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty aci...
Succinyldiaminopimelate Transaminase - A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer amino group from N-succinyl-L-2,...
Sulfate Adenylyltransferase - An enzyme that catalyzes the activation of sulfate ions by ATP to form adenosine-5'-phosphosulfate a...
Sulfotransferases - Enzymes which transfer sulfate groups to various acceptor molecules. They are involved in posttransl...
Sulfur Group Transferases - Enzymes that catalyze the transfer of sulfur atoms (2.8.1), sulfur groups (2.8.2) or coenzyme A (2.8...
Sulfurtransferases - Enzymes which transfer sulfur atoms to various acceptor molecules. EC 2.8.1....
Tankyrases - A group of telomere associated proteins that interact with TRF1 PROTEIN, contain ANKYRIN REPEATS and...
Taq Polymerase - A heat stable DNA-DIRECTED DNA POLYMERASE from the bacteria Thermus aquaticus. It is widely used for...
Telomerase - An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryot...
Thiamin Pyrophosphokinase - An enzyme that catalyzes the formation of thiamine pyrophosphate from ATP and thiamine. EC 2.7.6.2....
Thiosulfate Sulfurtransferase - An enzyme that catalyzes the transfer of the planetary sulfur atom of thiosulfate ion to cyanide ion...
Thymidine Kinase - An enzyme that catalyzes the conversion of ATP and thymidine to ADP and thymidine 5'-phosphate. Deox...
Thymidine Phosphorylase - The enzyme catalyzing the transfer of 2-deoxy-D-ribose from thymidine to orthophosphate, thereby lib...
Thymidylate Synthase - An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dU...
Transaldolase - An enzyme of the transferase class that catalyzes the reaction sedoheptulose 7-phosphate and D-glyce...
Transaminases - A subclass of enzymes of the transferase class that catalyze the transfer of an amino group from a d...
Transferases - Transferases are enzymes transferring a group, for example, the methyl group or a glycosyl group, fr...
Transferases (Other Substituted Phosphate Groups) - A class of enzymes that transfers substituted phosphate groups. EC 2.7.8....
Transglutaminases - Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in anot...
Transketolase - An enzyme of the transferase class that catalyzes the conversion of sedoheptulose 7-phosphate and D-...
Transposases - Enzymes that recombine DNA segments by a process which involves the formation of a synapse between t...
Transposon Resolvases - Recombinases that involved in the propagation of DNA TRANSPOSONS. They bind to transposon sequences ...
tRNA Methyltransferases - Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases with...
Tryptophan Transaminase - A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer amino group from L-TRYPTOPHAN to...
TYK2 Kinase - A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The...
Tyrosine Transaminase - An enzyme that catalyzes the conversion of L-TYROSINE and 2-oxoglutarate to 4-hydroxyphenylpyruvate ...
UDPglucose-Hexose-1-Phosphate Uridylyltransferase - An enzyme that catalyzes the transfer of UMP from UDPglucose to galactose 1-phosphate, forming UDPga...
Uridine Kinase - An enzyme that catalyzes the phosphorylation of uridine and cytidine to uridine 5'-phosphate and cyt...
Uridine Phosphorylase - An enzyme that catalyzes the transfer of ribose from uridine to orthophosphate, forming uracil and r...
UTP-Glucose-1-Phosphate Uridylyltransferase - An enzyme that catalyzes the formation of UDPglucose from UTP plus glucose 1-phosphate. EC 2.7.7.9....
UTP-Hexose-1-Phosphate Uridylyltransferase - An enzyme that catalyzes the synthesis of UDPgalactose from UTP and galactose-1-phosphate. It is pre...
Vacuolar Proton-Translocating ATPases - Proton-translocating ATPases that are involved in acidification of a variety of intracellular compar...
Vascular Endothelial Growth Factor Receptor-1 - A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis an...
Vascular Endothelial Growth Factor Receptor-2 - A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in en...
Vascular Endothelial Growth Factor Receptor-3 - A vascular endothelial cell growth factor receptor whose expression is restricted primarily to adult...
VDJ Recombinases - Recombinases involved in the rearrangement of immunity-related GENES such as IMMUNOGLOBULIN GENES an...
ZAP-70 Protein-Tyrosine Kinase - A protein tyrosine kinase that is required for T-CELL development and T-CELL ANTIGEN RECEPTOR functi...
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Diabetes Supplies | Diabetic Groups
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
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Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.