DNA Repair Enzymes
Categorical breakdown of terms falling inder the category of DNA Repair Enzymes. Sub categories will become more specific in nature to the terms listed for DNA Repair Enzymes.
Sub-Categories
Terms
Deoxyribodipyrimidine Photo-Lyase - An enzyme that catalyzes the reactivation by light of UV-irradiated DNA. It breaks two carbon-carbon...
DNA Glycosylases - A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzin...
DNA Ligases - Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of pre...
DNA Repair Enzymes - Enzymes that are involved in the reconstruction of a continuous two-stranded DNA molecule without mi...
DNA-(Apurinic or Apyrimidinic Site) Lyase - A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA ...
DNA-Formamidopyrimidine Glycosylase - A DNA repair enzyme that is an N-glycosyl hydrolase with specificity for DNA-containing ring-opened ...
MutS DNA Mismatch-Binding Protein - A methyl-directed mismatch DNA REPAIR protein that has weak ATPASE activity. MutS was originally des...
MutS Homolog 2 Protein - MutS homolog 2 protein is found throughout eukaryotes and is a homolog of the MUTS DNA MISMATCH-BIND...
Polynucleotide 5'-Hydroxyl-Kinase - An enzyme that catalyzes the transfer of a phosphate group to the 5'-terminal hydroxyl groups of DNA...
Thymine DNA Glycosylase - An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N...
Uracil-DNA Glycosidase - An enzyme that catalyzes the HYDROLYSIS of the N-glycosidic bond between sugar phosphate backbone an...
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
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Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
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Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.