Aryl Hydrocarbon Hydroxylases
Categorical breakdown of terms falling inder the category of Aryl Hydrocarbon Hydroxylases. Sub categories will become more specific in nature to the terms listed for Aryl Hydrocarbon Hydroxylases.
Sub-Categories
Terms
Aniline Hydroxylase - A drug-metabolizing, cytochrome P-450 enzyme which catalyzes the hydroxylation of aniline to hydroxy...
Aryl Hydrocarbon Hydroxylases - A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OX...
Benzopyrene Hydroxylase - A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyren...
Cytochrome P-450 CYP1A1 - A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as pol...
Cytochrome P-450 CYP1A2 - A cytochrome P-450 monooxygenase that can be induced by polycyclic aromatic xenobiotics in the liver...
Cytochrome P-450 CYP2B1 - A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTE...
Cytochrome P-450 CYP2D6 - A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals,...
Cytochrome P-450 CYP2E1 - An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solv...
Cytochrome P-450 CYP3A - A cytochrome P-450 monooxygenase that is involved in an NADPH-dependent electron transport pathway b...
Common Chronic Illnesses
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
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Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
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Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
