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Proteins

Categorical breakdown of terms falling inder the category of Proteins. Sub categories will become more specific in nature to the terms listed for Proteins.

Sub-Categories

Terms

14-3-3 Proteins - A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They ar...

25-Hydroxyvitamin D3 1-alpha-Hydroxylase - A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin...

2S Albumins, Plant - A major class of water-soluble seed storage proteins. Many proteins from this class are major PLANT ...

3',5'-Cyclic-AMP Phosphodiesterases - Enzymes that catalyze the hydrolysis of CYCLIC AMP to form adenosine 5'-phosphate. The enzymes are w...

3',5'-Cyclic-GMP Phosphodiesterases - Enzymes that catalyze the hydrolysis of cyclic GMP to yield guanosine-5'-phosphate....

4-1BB Ligand - A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPH...

A Kinase Anchor Proteins - A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether sp...

Abrin - A toxic lectin from the seeds of jequirity, Abrus precatorius L. Very active poison. Five different ...

Acetolactate Synthase - A flavoprotein enzyme that catalyzes the formation of acetolactate from 2 moles of PYRUVATE in the b...

Actin Capping Proteins - Actin capping proteins are cytoskeletal proteins that bind to the ends of ACTIN FILAMENTS to regulat...

Actin Depolymerizing Factors - A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel th...

Actinin - A protein factor that regulates the length of R-actin. It is chemically similar, but immunochemicall...

Actin-Related Protein 2 - A PROFILIN binding domain protein that is part of the Arp2-3 complex. It is related in sequence and ...

Actin-Related Protein 2-3 Complex - A complex of seven proteins including ARP2 PROTEIN and ARP3 PROTEIN that plays an essential role in ...

Actin-Related Protein 3 - A component of the Arp2-3 complex that is related in sequence and structure to ACTIN and that binds ...

Actins - Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filam...

Activated-Leukocyte Cell Adhesion Molecule - Cell adhesion molecule expressed on activated leukocytes, fibroblasts, and neurons. It is a ligand f...

Activating Transcription Factor 1 - An activating transcription factor that regulates expression of a variety of genes including C-JUN G...

Activating Transcription Factor 2 - An activating transcription factor that regulates expression of a variety of GENES including C-JUN G...

Activating Transcription Factor 3 - An activating transcription factor that plays a key role in cellular responses to GENOTOXIC STRESS a...

Activating Transcription Factor 4 - An activating transcription factor that regulates the expression of a variety of GENES involved in a...

Activating Transcription Factor 6 - One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protei...

Activating Transcription Factors - Activating transcription factors were originally identified as DNA-BINDING PROTEINS that interact wi...

Activin Receptors - Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREON...

Activin Receptors, Type I - One of the two types of ACTIVIN RECEPTORS or activin receptor-like kinases (ALK'S). There are severa...

Activin Receptors, Type II - One of the two types of ACTIVIN RECEPTORS. They are membrane protein kinases belonging to the family...

Activins - Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate...

Actomyosin - A protein complex of actin and MYOSINS occurring in muscle. It is the essential contractile substanc...

Acute-Phase Proteins - Proteins that are secreted into the blood in increased or decreased quantities by hepatocytes in res...

Acyl Carrier Protein - Consists of a polypeptide chain and 4'-phosphopantetheine linked to a serine residue by a phosphodie...

Acyl-CoA Dehydrogenase - A flavoprotein oxidoreductase that has specificity for medium-chain fatty acids. It forms a complex ...

Acyl-CoA Dehydrogenase, Long-Chain - A flavoprotein oxidoreductase that has specificity for long-chain fatty acids. It forms a complex wi...

Acyl-CoA Oxidase - An enzyme that catalyzes the first and rate-determining steps of peroxisomal beta-oxidation of fatty...

ADAM Proteins - A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. T...

Adaptor Protein Complex 1 - A clathrin adaptor protein complex primarily involved in clathrin-related transport at the TRANS-GOL...

Adaptor Protein Complex 2 - An adaptor protein complex primarily involved in the formation of clathrin-related endocytotic vesic...

Adaptor Protein Complex 3 - An adaptor protein complex found primarily on perinuclear compartments....

Adaptor Protein Complex 4 - An adaptor protein complex involved in transport of molecules between the TRANS-GOLGI NETWORK and th...

Adaptor Protein Complex alpha Subunits - A family of large adaptin protein subunits of approximately 100 kDa in size. They have been primaril...

Adaptor Protein Complex beta Subunits - A family of large adaptin protein complex subunits of approximately 90-130 kDa in size....

Adaptor Protein Complex delta Subunits - A family of large adaptin protein subunits of approximately 130-kDa in size. They have been primaril...

Adaptor Protein Complex gamma Subunits - A family of large adaptin protein subunits of approximately 90 KDa in size. They have been primarily...

Adaptor Protein Complex mu Subunits - A family of medium adaptin protein subunits of approximately 45 KDa in size. They have been primaril...

Adaptor Protein Complex sigma Subunits - A family of small adaptin protein complex subunits of approximately 19 KDa in size....

Adaptor Protein Complex Subunits - The subunits that make up the large, medium and small chains of adaptor proteins....

Adaptor Proteins, Signal Transducing - A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain...

Adaptor Proteins, Vesicular Transport - A class of proteins involved in the transport of molecules via TRANSPORT VESICLES. They perform func...

Adenine Nucleotide Translocator 1 - A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM) and ske...

Adenine Nucleotide Translocator 2 - A subtype of mitochondrial ADP, ATP translocase found primarily in FIBROBLASTS....

Adenine Nucleotide Translocator 3 - A subtype of mitochondrial ADP, ATP translocase found primarily in the LIVER....

Adenomatous Polyposis Coli Protein - A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GAR...

Adenovirus E1 Proteins - The very first viral gene products synthesized after cells are infected with adenovirus. The E1 regi...

Adenovirus E1A Proteins - Proteins transcribed from the E1A genome region of ADENOVIRUSES which are involved in positive regul...

Adenovirus E1B Proteins - Proteins transcribed from the E1B region of ADENOVIRUSES which are involved in regulation of the lev...

Adenovirus E2 Proteins - Proteins transcribed from the E2 region of ADENOVIRUSES. Several of these are required for viral DNA...

Adenovirus E3 Proteins - Proteins transcribed from the E3 region of ADENOVIRUSES but not essential for viral replication. The...

Adenovirus E4 Proteins - Proteins transcribed from the E4 region of ADENOVIRUSES. The E4 19K protein transactivates transcrip...

Adenovirus Early Proteins - Proteins encoded by adenoviruses that are synthesized prior to, and in the absence of, viral DNA rep...

Adenylate Cyclase - An enzyme of the lyase class that catalyzes the formation of CYCLIC AMP and pyrophosphate from ATP. ...

Adhesins, Bacterial - Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to o...

Adhesins, Escherichia coli - Thin, filamentous protein structures, including proteinaceous capsular antigens (fimbrial antigens),...

Adipokines - Polypeptides produced by the ADIPOCYTES. They include LEPTIN; ADIPONECTIN; RESISTIN; and many cytoki...

Adiponectin - A 30-kDa COMPLEMENT C1Q-related protein, the most abundant gene product secreted by FAT CELLS of the...

ADP-Ribosylation Factor 1 - ADP-RIBOSYLATION FACTOR 1 is involved in regulating intracellular transport by modulating the intera...

ADP-Ribosylation Factors - MONOMERIC GTP-BINDING PROTEINS that were initially recognized as allosteric activators of the MONO(A...

Adrenocorticotropic Hormone - An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROI...

Adrenodoxin - An iron-sulfur protein which serves as an electron carrier in enzymatic steroid hydroxylation reacti...

Aequorin - A photoprotein isolated from the bioluminescent jellyfish Aequorea. It emits visible light by an int...

AGAMOUS Protein, Arabidopsis - A plant homeotic protein involved in the development of stamens and carpels of Arabidopsis thaliana....

Aggrecans - Large HYALURONAN-containing proteoglycans found in articular cartilage (CARTILAGE, ARTICULAR). They ...

Agouti Signaling Protein - A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthe...

Agouti-Related Protein - A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and ...

Agrin - A protein component of the synaptic basal lamina. It has been shown to induce clustering of acetylch...

Albumins - Water-soluble proteins found in egg whites, blood, lymph, and other tissues and fluids. They coagula...

Aldosterone Synthase - A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presen...

Algal Proteins - Proteins found in any species of algae....

alpha 1-Antichymotrypsin - Glycoprotein found in alpha(1)-globulin region in human serum. It inhibits chymotrypsin-like protein...

alpha 1-Antitrypsin - Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; an...

alpha Catenin - A catenin that binds F-ACTIN and links the CYTOSKELETON with BETA CATENIN and GAMMA CATENIN....

alpha Karyopherins - Nucleocytoplasmic transport molecules that bind to the NUCLEAR LOCALIZATION SIGNALS of cytoplasmic m...

alpha-2-Antiplasmin - A member of the serpin superfamily found in plasma that inhibits the lysis of fibrin clots which are...

alpha-Crystallin A Chain - One of the subunits of alpha-crystallins. Unlike ALPHA-CRYSTALLIN B CHAIN the expression of ALPHA-CR...

alpha-Crystallin B Chain - One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE)...

alpha-Crystallins - A subclass of crystallins that provides the majority of refractive power and translucency to the len...

alpha-Defensins - DEFENSINS found in azurophilic granules of neutrophils and in the secretory granules of intestinal ...

alpha-Endorphin - An endogenous opioid peptide derived from BETA-LIPOTROPIN of the pro-opiomelanocortin (POMC) system....

alpha-Fetoproteins - The first alpha-globulins to appear in mammalian sera during development of the embryo and the domin...

alpha-Globins - Members of the alpha-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 16. ...

Alpha-Globulins - Serum proteins that have the most rapid migration during ELECTROPHORESIS. This subgroup of globulins...

alpha-Macroglobulins - Glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrop...

alpha-MSH - A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-term...

alpha-Synuclein - A synuclein that is a major component of LEWY BODIES that plays a role in neurodegeneration and neur...

Amelogenin - A major dental enamel-forming protein found in mammals. In humans the protein is encoded by GENES fo...

Amino Acid Transport System A - A sodium-dependent neutral amino acid transporter that accounts for most of the sodium-dependent neu...

Amino Acid Transport System ASC - A ubiquitous sodium-dependent neutral amino acid transporter. The preferred substrates for this tran...

Amino Acid Transport System L - A sodium-independent neutral amino acid transporter system with specificity for large amino acids. O...

Amino Acid Transport System X-AG - A family of POTASSIUM and SODIUM-dependent acidic amino acid transporters that demonstrate a high af...

Amino Acid Transport System y+ - A sodium-independent, basic amino acid transport system with a high-affinity for LYSINE; ARGININE; a...

Amino Acid Transport System y+L - A leucine-sensitive amino acid transport system with high affinity for basic amino acids( AMINO ACID...

Amino Acid Transport Systems - Cellular proteins and protein complexes that transport amino acids across biological membranes....

Amino Acid Transport Systems, Acidic - Amino acid transporter systems capable of transporting acidic amino acids (AMINO ACIDS, ACIDIC)....

Amino Acid Transport Systems, Basic - Amino acid transporter systems capable of transporting basic amino acids (AMINO ACIDS, BASIC)....

Amino Acid Transport Systems, Neutral - Amino acid transporter systems capable of transporting neutral amino acids (AMINO ACIDS, NEUTRAL)....

AMP-Activated Protein Kinases - Intracellular signaling protein kinases that play a signaling role in the regulation of cellular ene...

Amphibian Proteins - Proteins obtained from species in the class of AMPHIBIANS....

Amyloid - A type of extracellularly deposited substance composed of an amyloid protein and additional componen...

Amyloid beta-Protein - A 4-kDa protein, 39-43 amino acids long, expressed by a gene located on chromosome 21. It is the maj...

Amyloid beta-Protein Precursor - A precursor to the AMYLOID BETA-PROTEIN (beta/A4). Alterations in the expression of the amyloid beta...

Anaphylatoxins - Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They i...

Androgen-Binding Protein - Carrier proteins produced in the Sertoli cells of the testis, secreted into the seminiferous tubules...

Angiogenic Proteins - Intercellular signaling peptides and proteins that regulate the proliferation of new blood vessels u...

Angiopoietin-1 - The first to be discovered member of the angiopoietin family. It may play a role in increasing the s...

Angiopoietin-2 - An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without re...

Angiopoietins - A family of structurally-related angiogenic proteins of approximately 70 kDa in size. They have high...

Angiostatic Proteins - Proteins that specifically inhibit the growth of new blood vessels (ANGIOGENESIS, PHYSIOLOGIC)....

Angiostatins - Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives fro...

Angiotensin I - A decapeptide that is cleaved from precursor angiotensinogen by RENIN. Angiotensin I has limited bio...

Angiotensin II - An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after ...

Angiotensin III - A heptapeptide formed from ANGIOTENSIN II after the removal of an amino acid at the N-terminal by AM...

Angiotensinogen - An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver an...

Angiotensins - Oligopeptides which are important in the regulation of blood pressure (VASOCONSTRICTION) and fluid h...

Aniline Hydroxylase - A drug-metabolizing, cytochrome P-450 enzyme which catalyzes the hydroxylation of aniline to hydroxy...

Anion Exchange Protein 1, Erythrocyte - A ubiquitous membrane transport protein found in the plasma membrane of diverse cell types and tissu...

Anion Transport Proteins - Membrane proteins whose primary function is to facilitate the transport of negatively charged molecu...

Anistreplase - An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection, the acy...

Ankyrins - A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythro...

Annexin A1 - Protein of the annexin family exhibiting lipid interaction and steroid-inducibility....

Annexin A2 - A member of the annexin family that is a substrate for a tyrosine kinase, ONCOGENE PROTEIN PP60(V-SR...

Annexin A3 - A protein of the annexin family that catalyzes the conversion of 1-D-inositol 1,2-cyclic phosphate a...

Annexin A4 - Protein of the annexin family originally isolated from the electric organ of the electric ray Torped...

Annexin A5 - A protein of the annexin family isolated from human PLACENTA and other tissues. It inhibits cytosoli...

Annexin A6 - Protein of the annexin family with a probable role in exocytotic and endocytotic membrane events....

Annexin A7 - An annexin family member that plays a role in MEMBRANE FUSION and signaling via VOLTAGE-DEPENDENT CA...

Annexins - Family of calcium- and phospholipid-binding proteins which are structurally related and exhibit immu...

Antennapedia Homeodomain Protein - Antennapedia homeodomain protein is a homeobox protein involved in limb patterning in ARTHROPODS. Mu...

Antibodies - Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only...

Antibodies, Anticardiolipin - Antiphospholipid antibodies found in association with systemic lupus erythematosus (LUPUS ERYTHEMATO...

Antibodies, Anti-Idiotypic - Antibodies which react with the individual structural determinants (idiotopes) on the variable regio...

Antibodies, Antineutrophil Cytoplasmic - Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONO...

Antibodies, Antinuclear - Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclea...

Antibodies, Antiphospholipid - Autoantibodies directed against phospholipids. These antibodies are characteristically found in pati...

Antibodies, Archaeal - Immunoglobulins induced by substances elaborated by ARCHAEA that have an antigenic activity....

Antibodies, Bacterial - Immunoglobulins induced by substances elaborated by BACTERIA that have an antigenic activity....

Antibodies, Bispecific - Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIG...

Antibodies, Blocking - Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTE...

Antibodies, Catalytic - Antibodies that can catalyze a wide variety of chemical reactions. They are characterized by high su...

Antibodies, Fungal - Immunoglobulins induced by substances elaborated by FUNGI that have an antigenic activity....

Antibodies, Helminth - Antibodies produced by human or animal cells following clinical or experimental exposure to parasiti...

Antibodies, Heterophile - Antibodies elicited in a different species from which the antigen originated. These antibodies are d...

Antibodies, Immobilized - Antibodies that are chemically bound to a substrate material which renders their location fixed....

Antibodies, Monoclonal - Antibodies produced by clones of cells such as those isolated after hybridization of activated B LYM...

Antibodies, Neoplasm - Immunoglobulins induced by antigens specific for tumors other than the normally occurring HISTOCOMPA...

Antibodies, Neutralizing - Antibodies that reduce or abolish some biological activity of a soluble antigen or infectious agent,...

Antibodies, Phospho-Specific - Antibodies directed against immunogen-coupled phosphorylated PEPTIDES corresponding to amino acids s...

Antibodies, Protozoan - Antibodies produced by human or animal cells following clinical or experimental exposure to parasiti...

Antibodies, Viral - Immunoglobulins produced as a response to VIRAL ANTIGENS; includes all classes of immunoglobulins el...

Antifreeze Proteins - Proteins that bind to ice and modify the growth of ice crystals. They perform a cryoprotective role ...

Antifreeze Proteins, Type I - A subclass of ANTIFREEZE PROTEINS that are 3-5 kDa in size and contain a single alanine-rich amphipa...

Antifreeze Proteins, Type II - A subclass of ANTIFREEZE PROTEINS that have a cystine-rich globular structure of approximately 14 kD...

Antifreeze Proteins, Type III - A subclass of ANTIFREEZE PROTEINS that are globular, 6.5 kDa in size and contain compact beta-sheet ...

Antifreeze Proteins, Type IV - A subclass of ANTIFREEZE PROTEINS that contain four amphipathic alpha-helices folded into an antipar...

Antigen-Antibody Complex - The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen...

Antigens, CD11a - An alpha-integrin subunit found on lymphocytes, granulocytes, macrophages and monocytes. It combines...

Antigens, CD11b - A CD antigen that contains a conserved I domain which is involved in ligand binding. When combined ...

Antigens, CD11c - An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels ...

Antigens, CD137 - A member of the tumor necrosis factor receptor superfamily that is specific for 4-1BB LIGAND. It is ...

Antigens, CD14 - Glycolipid-anchored membrane glycoproteins expressed on cells of the myelomonocyte lineage including...

Antigens, CD146 - A cell adhesion molecule of the immunoglobulin superfamily that is expressed in ENDOTHELIAL CELLS an...

Antigens, CD147 - A widely distributed cell surface transmembrane glycoprotein that stimulates the synthesis of MATRIX...

Antigens, CD164 - A sialomucin protein that functions as a cell adhesion molecule. It is a negative regulator of certa...

Antigens, CD18 - Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the...

Antigens, CD22 - A lectin and cell adhesion molecule found in B-LYMPHOCYTES. It interacts with SIALIC ACIDS and media...

Antigens, CD24 - A cell adhesion protein that was originally identified as a heat stable antigen in mice. It is invol...

Antigens, CD27 - A member of the tumor necrosis factor receptor superfamily found on most T-LYMPHOCYTES. Activation ...

Antigens, CD28 - T-cell differentiation antigens that serve as the receptors for the B7 antigen (ANTIGENS, CD80) whic...

Antigens, CD29 - Integrin beta-1 chains which are expressed as heterodimers that are noncovalently associated with sp...

Antigens, CD30 - A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of...

Antigens, CD31 - Cell adhesion molecules present on virtually all monocytes, platelets, and granulocytes. CD31 is hig...

Antigens, CD36 - Leukocyte differentiation antigens and major platelet membrane glycoproteins present on MONOCYTES; E...

Antigens, CD4 - 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. C...

Antigens, CD40 - A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is f...

Antigens, CD43 - A sialic acid-rich protein and an integral cell membrane mucin. It plays an important role in activa...

Antigens, CD44 - Acidic sulfated integral membrane glycoproteins expressed in several alternatively spliced and varia...

Antigens, CD45 - High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopo...

Antigens, CD46 - A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves...

Antigens, CD47 - A ubiquitously expressed membrane glycoprotein. It interacts with a variety of INTEGRINS and mediate...

Antigens, CD55 - Glycoproteins broadly distributed among hematopoietic and non-hematopoietic cells. CD55 prevents the...

Antigens, CD56 - The 140 kDa isoform of NCAM (neural cell adhesion molecule) containing a transmembrane domain and sh...

Antigens, CD58 - Glycoproteins with a wide distribution on hematopoietic and non-hematopoietic cells and strongly exp...

Antigens, CD59 - Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cyto...

Antigens, CD70 - A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds t...

Antigens, CD79 - A component of the B-cell antigen receptor that is involved in B-cell antigen receptor heavy chain t...

Antigens, CD86 - A CD antigen that plays a role in T-lymphocyte proliferation and interleukin 2 production. It is a c...

Antigens, CD95 - A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES....

Antigens, CD98 - A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The in...

Antigens, CD98 Heavy Chain - A transmembrane glycoprotein subunit that can dimerize with a variety of light chain subunits (ANTIG...

Antigens, CD98 Light Chains - A family of light chains that bind to the CD98 heavy chain (ANTIGENS, CD98 HEAVY CHAIN) to form a he...

Antigens, Nuclear - Immunologically detectable substances found in the CELL NUCLEUS....

Antigens, Polyomavirus Transforming - Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is nece...

Antigens, Thy-1 - A group of differentiation surface antigens, among the first to be discovered on thymocytes and T-ly...

Antilymphocyte Serum - Serum containing GAMMA-GLOBULINS which are antibodies for lymphocyte ANTIGENS. It is used both as a ...

Antimicrobial Cationic Peptides - Small cationic peptides that are an important component, in most species, of early innate and induce...

Antiporters - Membrane transporters that co-transport two or more dissimilar molecules in the opposite direction a...

Antistreptolysin - Antibodies specific to STREPTOLYSINS which indicate STREPTOCOCCAL INFECTIONS....

Antithrombin III - A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and...

Antithrombins - An endogenous family of proteins belonging to the serpin superfamily that neutralizes the action of ...

Antitoxins - Antisera from immunized animals that is purified and used as a passive immunizing agent against spec...

Antivenins - Antisera used to counteract poisoning by animal VENOMS, especially SNAKE VENOMS....

Apoenzymes - The protein components of enzyme complexes (HOLOENZYMES). An apoenzyme is the holoenzyme minus any c...

Apoferritins - The protein components of ferritins. Apoferritins are shell-like structures containing nanocavities ...

Apolipoprotein A-I - The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an a...

Apolipoprotein A-II - The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid ...

Apolipoprotein B-100 - A 513-kDa protein synthesized in the LIVER. It serves as the major structural protein of low-density...

Apolipoprotein B-48 - A 241-kDa protein synthesized only in the INTESTINES. It serves as a structural protein of CHYLOMICR...

Apolipoprotein C-I - A 6.6-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS; INTERMEDIATE-DENSITY LIPOPROTEINS; and...

Apolipoprotein C-II - A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN L...

Apolipoprotein C-III - A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synt...

Apolipoprotein E2 - One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at...

Apolipoprotein E3 - A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is...

Apolipoprotein E4 - A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLI...

Apolipoproteins - Protein components on the surface of LIPOPROTEINS. They form a layer surrounding the hydrophobic lip...

Apolipoproteins A - Structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS), including APOLIPOPROTEIN ...

Apolipoproteins B - Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein ...

Apolipoproteins C - A group of apolipoproteins that can readily exchange among the various classes of lipoproteins (HDL;...

Apolipoproteins D - A glycoprotein component of HIGH-DENSITY LIPOPROTEINS that transports small hydrophobic ligands incl...

Apolipoproteins E - A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPO...

Apoprotein(a) - A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity ...

Apoproteins - The protein components of a number of complexes, such as enzymes (APOENZYMES), ferritin (APOFERRITIN...

Apoptosis Inducing Factor - A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS w...

Apoptosis Regulatory Proteins - A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PRO...

Apoptotic Protease-Activating Factor 1 - A CARD signaling adaptor protein that plays a role in the mitochondria-stimulated apoptosis (APOPTOS...

Aprotinin - A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is a...

Aquaglyceroporins - A subgroup of aquaporins that transport WATER; GLYCEROL; and other small solutes across CELL MEMBRAN...

Aquaporin 1 - Aquaporin 1 forms a water-specific channel that is constitutively expressed at the PLASMA MEMBRANE o...

Aquaporin 2 - Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The tr...

Aquaporin 3 - Aquaporin 3 is an aquaglyceroporin that is expressed in the KIDNEY COLLECTING DUCTS and is constitut...

Aquaporin 4 - Aquaporin 4 is the major water-selective channel in the CENTRAL NERVOUS SYSTEM of mammals....

Aquaporin 5 - Aquaporin 5 is a water-specific channel protein that is expressed primarily in alveolar, tracheal, a...

Aquaporin 6 - Aquaporin 6 is an aquaglyceroporin that is found primarily in KIDNEY COLLECTING DUCTS. AQP6 protein ...

Aquaporins - A class of porins that allow the passage of WATER and other small molecules across CELL MEMBRANES....

Arabidopsis Proteins - Proteins that originate from plants species belonging to the genus ARABIDOPSIS. The most intensely s...

AraC Transcription Factor - A transcription factor found in BACTERIA that positively and negatively regulates the expression of ...

Arachidonate 12-Lipoxygenase - An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-H...

Arachidonate 15-Lipoxygenase - An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-H...

Arachidonate 5-Lipoxygenase - An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPE...

Arachidonate Lipoxygenases - Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates. These products are...

Archaeal Proteins - Proteins found in any species of archaeon....

Arginine Vasopressin - The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE a...

Armadillo Domain Proteins - A family of proteins that contain several 42-amino acid repeat domains and are homologous to the Dro...

ARNTL Transcription Factors - Basic helix-loop-helix (bHLH) domain-containing proteins that play important roles in CIRCADIAN RHYT...

Aromatase - An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and convert...

Arrestin - A 48-Kd protein of the outer segment of the retinal rods and a component of the phototransduction ca...

Arrestins - Regulatory proteins that down-regulate phosphorylated G-protein membrane receptors, including rod an...

Arsenite Transporting ATPases - Efflux pumps that use the energy of ATP hydrolysis to pump arsenite across a membrane. They are prim...

Aryl Hydrocarbon Hydroxylases - A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OX...

Aryl Hydrocarbon Receptor Nuclear Translocator - Aryl hydrocarbon receptor nuclear translocator is a basic HELIX-LOOP-HELIX MOTIF containing protein ...

Asialoglycoprotein Receptor - A C-type lectin that is a cell surface receptor for ASIALOGLYCOPROTEINS. It is found primarily in th...

Asialoglycoproteins - Endogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They b...

ATP-Binding Cassette Transporters - A family of MEMBRANE TRANSPORT PROTEINS that require ATP hydrolysis for the transport of substrates ...

Atrial Myosins - Myosin type II isoforms specifically found in the atrial muscle of the heart....

Autoantibodies - Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them....

Autocrine Motility Factor - A protein cytokine secreted by tumor cells. It elicits increases in cell motility and phosphoinositi...

Autoreceptors - Transmitter receptors on or near presynaptic terminals (or varicosities) which are sensitive to the ...

Auxilins - A family of proteins that play a role as cofactors in the process of CLATHRIN recycling in cells....

Avian Proteins - Proteins obtained from species of BIRDS....

Avidin - A specific protein in egg albumin that interacts with BIOTIN to render it unavailable to mammals, th...

Azurin - A bacterial protein from Pseudomonas, Bordetella, or Alcaligenes which operates as an electron trans...

Bacterial Capsules - An envelope of loose gel surrounding a bacterial cell which is associated with the virulence of path...

Bacterial Outer Membrane Proteins - Proteins isolated from the outer membrane of Gram-negative bacteria....

Bacterial Proteins - Proteins found in any species of bacterium....

Bacterial Proton-Translocating ATPases - Membrane-bound proton-translocating ATPases that serve two important physiological functions in bact...

Bacterial Transferrin Receptor Complex - A complex of proteins that forms a receptor for TRANSFERRIN in BACTERIA. Many pathogenic bacteria ut...

Bacteriochlorophyll A - A specific bacteriochlorophyll that is similar in structure to chlorophyll a....

Bacteriochlorophylls - Pyrrole containing pigments found in photosynthetic bacteria....

Bacteriocins - Substances elaborated by specific strains of bacteria that are lethal against other strains of the s...

Bacteriorhodopsins - Rhodopsins found in the PURPLE MEMBRANE of halophilic archaea such as HALOBACTERIUM HALOBIUM. Bacter...

Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - A family of transcription factors that contain regions rich in basic residues, LEUCINE ZIPPER domain...

Basic Helix-Loop-Helix Transcription Factors - A family of DNA-binding transcription factors that contain a basic HELIX-LOOP-HELIX MOTIF....

Basic-Leucine Zipper Transcription Factors - A large superfamily of transcription factors that contain a region rich in BASIC AMINO ACID residues...

B-Cell Activating Factor - A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survi...

B-Cell Activation Factor Receptor - A member of the tumor necrosis factor receptor superfamily that specifically binds B-CELL ACTIVATING...

B-Cell Maturation Antigen - A member of the tumor necrosis factor receptor superfamily found on mature B-LYMPHOCYTES. It has spe...

B-Cell-Specific Activator Protein - A transcription factor that is essential for CELL DIFFERENTIATION of B-LYMPHOCYTES. It functions bot...

bcl-2 Homologous Antagonist-Killer Protein - A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein in...

bcl-2-Associated X Protein - A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It re...

bcl-Associated Death Protein - A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION....

bcl-X Protein - A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS. Two major iso...

Bence Jones Protein - An abnormal protein with unusual thermosolubility characteristics that is found in the urine of pati...

Benzopyrene Hydroxylase - A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyren...

beta 2-Glycoprotein I - A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOP...

beta 2-Microglobulin - An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the ...

beta Catenin - A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin bi...

beta Karyopherins - Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involve...

beta-Adrenergic Receptor Kinases - G-protein-coupled receptor kinases that mediate agonist-dependent PHOSPHORYLATION and desensitizatio...

beta-Crystallin A Chain - The acidic subunit of beta-crystallins....

beta-Crystallin B Chain - The basic subunit of beta-crystallins....

beta-Crystallins - A class of crystallins that provides refractive power and translucency to the lens (LENS, CRYSTALLIN...

beta-Defensins - DEFENSINS found mainly in epithelial cells....

beta-Endorphin - A 31-amino acid peptide that is the C-terminal fragment of BETA-LIPOTROPIN. It acts on OPIOID RECEPT...

beta-Globins - Members of the beta-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 11. T...

Beta-Globulins - Serum proteins with an electrophoretic mobility that falls between ALPHA-GLOBULINS and GAMMA-GLOBULI...

beta-Keratins - Keratins that form into a beta-pleated sheet structure. They are principle constituents of the corne...

beta-Lipotropin - A 90-amino acid peptide derived from post-translational processing of pro-opiomelanocortin (POMC) in...

beta-MSH - An 18-amino acid peptide that is the C-terminal fragment of gamma-lipotropin which is the N-terminal...

beta-Synuclein - A synuclein that is closely related to ALPHA-SYNUCLEIN. It may play a neuroprotective role against s...

beta-Thromboglobulin - A platelet-specific protein which is released when platelets aggregate. Elevated plasma levels have ...

beta-Transducin Repeat-Containing Proteins - A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of ...

BH3 Interacting Domain Death Agonist Protein - A member of the Bcl-2 protein family that reversibly binds MEMBRANES. It is a pro-apoptotic protein ...

Binding Sites, Antibody - Local surface sites on antibodies which react with antigen determinant sites on antigens. They are f...

Blood Coagulation Factors - Endogenous substances, usually proteins, that are involved in the blood coagulation process....

Blood Proteins - Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and ma...

Bombesin - A tetradecapeptide originally obtained from the skins of toads Bombina bombina and B. variegata. It ...

Bone Morphogenetic Protein 1 - A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase do...

Bone Morphogenetic Protein 15 - A protein that plays a role in GRANULOSA CELLS where it regulates folliculogenesis. Mutations in the...

Bone Morphogenetic Protein 2 - A potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor...

Bone Morphogenetic Protein 3 - A bone morphogenetic protein that is found at high concentrations in a purified osteoinductive prote...

Bone Morphogenetic Protein 4 - A bone morphogenetic protein that is a potent inducer of bone formation. It also functions as a regu...

Bone Morphogenetic Protein 5 - A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator o...

Bone Morphogenetic Protein 6 - A bone morphogenetic protein that is a potent inducer of BONE formation. It plays additional roles i...

Bone Morphogenetic Protein 7 - A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a pot...

Bone Morphogenetic Protein Receptors - A family of CELL SURFACE RECEPTORS that bind BONE MORPHOGENETIC PROTEINS. They are PROTEIN-SERINE-TH...

Bone Morphogenetic Protein Receptors, Type I - A subtype of bone morphogenetic protein receptors with high affinity for BONE MORPHOGENETIC PROTEINS...

Bone Morphogenetic Protein Receptors, Type II - A subtype of bone morphogenetic protein receptors with low affinity for BONE MORPHOGENETIC PROTEINS....

Bone Morphogenetic Proteins - Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily o...

Botulinum Antitoxin - Antiserum given therapeutically in BOTULISM....

Botulinum Toxin Type A - A 150 kDa neurotoxic protein produced by CLOSTRIDIUM BOTULINUM. When consumed in contaminated food i...

Botulinum Toxins - Proteins synthesized as a single chain of ~150 kDa with 35% sequence identity to TETANUS TOXIN that ...

Bradykinin - A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a pote...

Brain-Derived Neurotrophic Factor - A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic actio...

BRCA1 Protein - The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). In normal cells the BRCA1 protein is loc...

BRCA2 Protein - A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose...

Buserelin - A potent synthetic agonist of GONADOTROPIN-RELEASING HORMONE with D-serine substitution at residue 6...

Butyrate Response Factor 1 - A ZINC FINGER MOTIF containing immediate early protein that is closely related to TRISTETRAPROLIN. I...

Butyryl-CoA Dehydrogenase - A flavoprotein oxidoreductase that has specificity for short-chain fatty acids. It forms a complex w...

Cadherins - Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS ...

Caenorhabditis elegans Proteins - Proteins from the nematode species CAENORHABDITIS ELEGANS. The proteins from this species are the su...

Calcineurin - A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calc...

Calcitonin - A peptide hormone that lowers calcium concentration in the blood. In humans, it is released by thyro...

Calcitonin Gene-Related Peptide - Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs...

Calcium Channels - Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are catego...

Calcium Channels, L-Type - Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They ar...

Calcium Channels, N-Type - CALCIUM CHANNELS that are concentrated in neural tissue. Omega toxins inhibit the actions of these c...

Calcium Channels, P-Type - CALCIUM CHANNELS located within the PURKINJE CELLS of the cerebellum. They are involved in stimulati...

Calcium Channels, Q-Type - CALCIUM CHANNELS located in the neurons of the brain....

Calcium Channels, R-Type - CALCIUM CHANNELS located in the neurons of the brain. They are inhibited by the marine snail toxin, ...

Calcium Channels, T-Type - A heterogenous group of transient or low voltage activated type CALCIUM CHANNELS. They are found in ...

Calcium-Binding Protein, Vitamin D-Dependent - A protein that plays a fundamental role in the Vitamin D mediated transport of calcium in reptiles, ...

Calcium-Binding Proteins - Proteins to which calcium ions are bound. They can act as transport proteins, regulator proteins, or...

Calcium-Calmodulin-Dependent Protein Kinase Kinase - A regulatory calcium-calmodulin-dependent protein kinase that specifically phosphorylates CALCIUM-CA...

Calcium-Calmodulin-Dependent Protein Kinase Type 1 - A monomeric calcium-calmodulin-dependent protein kinase subtype that is expressed in a broad variety...

Calcium-Calmodulin-Dependent Protein Kinase Type 2 - A multifunctional calcium-calmodulin-dependent protein kinase subtype that occurs as an oligomeric p...

Calcium-Calmodulin-Dependent Protein Kinase Type 4 - A monomeric calcium-calmodulin-dependent protein kinase subtype that is primarily expressed in neuro...

Calcium-Calmodulin-Dependent Protein Kinases - A CALMODULIN-dependent enzyme that catalyzes the phosphorylation of proteins. This enzyme is also so...

Calcium-Transporting ATPases - Cation-transporting proteins that utilize the energy of ATP hydrolysis for the transport of CALCIUM....

Calgranulin A - A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocompl...

Calgranulin B - A 13.2-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocompl...

Calmodulin - A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The bindi...

Calmodulin-Binding Proteins - Proteins which bind calmodulin. They are found in many tissues and have a variety of functions inclu...

Calnexin - A lectin found in ENDOPLASMIC RETICULUM membranes that binds to specific N-linked OLIGOSACCHARIDES f...

Calreticulin - A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASM...

Calsequestrin - Acidic protein found in SARCOPLASMIC RETICULUM that binds calcium to the extent of 700-900 nmoles/mg...

Camphor 5-Monooxygenase - A soluble cytochrome P-450 enzyme that catalyzes camphor monooxygenation in the presence of putidare...

Capsid Proteins - Proteins that form the CAPSID of VIRUSES....

CapZ Actin Capping Protein - An actin capping protein that binds to the barbed-ends of ACTIN filaments. It is a heterodimer consi...

Carcinoembryonic Antigen - A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tr...

CARD Signaling Adaptor Proteins - A family of intracellular signaling adaptor proteins that contain caspase activation and recruitment...

Cardiac Myosins - Myosin type II isoforms found in cardiac muscle....

Carnosine - A naturally occurring dipeptide neuropeptide found in muscles....

Carrier Proteins - Transport proteins that carry specific substances in the blood or across cell membranes....

Casein Kinase I - A casein kinase that was originally described as a monomeric enzyme with a molecular weight of 30-40...

Casein Kinase Ialpha - A casein kinase I isoenzyme that plays a role in intracellular signaling pathways including the CELL...

Casein Kinase Idelta - A casein kinase I isoenzyme that plays a regulatory role in a variety of cellular functions includin...

Casein Kinase Iepsilon - A casein kinase I isoenzyme with specificity for proteins involved the regulation of the CIRCADIAN R...

Casein Kinase II - A ubiquitous casein kinase that is comprised of two distinct catalytic subunits and dimeric regulato...

Casein Kinases - A group of protein-serine-threonine kinases that was originally identified as being responsible for ...

Caseins - A mixture of related phosphoproteins occurring in milk and cheese. The group is characterized as one...

CASP8 and FADD-Like Apoptosis Regulating Protein - An APOPTOSIS-regulating protein that is structurally related to CASPASE 8 and competes with CASPASE ...

Caspase 1 - A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays...

Caspase 10 - A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation...

Caspase 12 - A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspa...

Caspase 14 - A short pro-domain caspase that is almost exclusively expressed in the EPIDERMIS and may play a role...

Caspase 2 - A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activ...

Caspase 3 - A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CA...

Caspase 6 - A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CA...

Caspase 7 - A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CA...

Caspase 8 - A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 ...

Caspase 9 - A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspa...

Caspases - A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and AP...

Caspases, Effector - A subclass of caspases that contain short pro-domain regions. They are activated by the proteolytic ...

Caspases, Initiator - A subtype of caspases that contain long pro-domain regions that regulate the activation of the enzym...

Catecholamine Plasma Membrane Transport Proteins - A group of membrane transport proteins that transport biogenic amine derivatives of catechol across ...

Catenins - A family of cytoskeletal proteins that play essential roles in CELL ADHESION at ADHERENS JUNCTIONS b...

Cathelicidins - Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a mo...

Cation Transport Proteins - Membrane proteins whose primary function is to facilitate the transport of positively charged molecu...

Cationic Amino Acid Transporter 1 - A high-affinity, low capacity system y+ amino acid transporter found ubiquitously. It has specificit...

Cationic Amino Acid Transporter 2 - A high-affinity, low capacity system y+ amino acid transporter with strong similarity to CATIONIC AM...

Caveolin 1 - A tyrosine phosphoprotein that plays an essential role in CAVEOLAE formation. It binds CHOLESTEROL a...

Caveolin 2 - Caveolin 2 is a binding partner of CAVEOLIN 1. It undergoes tyrosine phosphorylation by C-SRC PROTEI...

Caveolin 3 - A caveolin that is expressed exclusively in MUSCLE CELLS and is sufficient to form CAVEOLAE in SARCO...

Caveolins - The main structural proteins of CAVEOLAE. Several distinct genes for caveolins have been identified....

CCAAT-Binding Factor - A heterotrimeric DNA-binding protein that binds to CCAAT motifs in the promoters of eukaryotic genes...

CCAAT-Enhancer-Binding Protein-alpha - A CCAAT-enhancer-binding protein found in LIVER; ADIPOSE TISSUE; INTESTINES; LUNG; ADRENAL GLANDS; P...

CCAAT-Enhancer-Binding Protein-beta - A CCAAT-enhancer-binding protein found in LIVER; INTESTINES; LUNG and ADIPOSE TISSUE. It is an impor...

CCAAT-Enhancer-Binding Protein-delta - A member of the C-EBP protein family of transcription factors. It plays a key role in G0 PHASE mamma...

CCAAT-Enhancer-Binding Proteins - A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT....

CCN Intercellular Signaling Proteins - A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface recept...

CD30 Ligand - A membrane-bound tumor necrosis family member found primarily on activated T-LYMPHOCYTES that binds ...

CD4 Immunoadhesins - Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunog...

CD40 Ligand - A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds t...

CDC2 Protein Kinase - Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL ...

cdc25 Phosphatases - A subclass of dual specificity phosphatases that play a role in the progression of the CELL CYCLE. T...

CDC28 Protein Kinase, S cerevisiae - A protein kinase encoded by the Saccharomyces cerevisiae CDC28 gene and required for progression fro...

CDC2-CDC28 Kinases - A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE; S CE...

cdc42 GTP-Binding Protein - A member of the Rho family of MONOMERIC GTP-BINDING PROTEINS. It is associated with a diverse array ...

cdc42 GTP-Binding Protein, Saccharomyces cerevisiae - A member of the Rho family of MONOMERIC GTP-BINDING PROTEINS from SACCHAROMYCES CEREVISIAE. It is in...

Cecropins - Antimicrobial peptides that form channels in membranes that are more permeable to anions than cation...

Cell Adhesion Molecules - Surface ligands, usually glycoproteins, that mediate cell-to-cell adhesion. Their functions include ...

Cell Adhesion Molecules, Neuronal - Surface ligands that mediate cell-to-cell adhesion and function in the assembly and interconnection ...

Cell Adhesion Molecules, Neuron-Glia - Cell adhesion molecules that mediate neuron-neuron adhesion and neuron-astrocyte adhesion. They are ...

Cell Cycle Proteins - Proteins that control the CELL DIVISION CYCLE. This family of proteins includes a wide variety of cl...

Cell Wall Skeleton - A mucoprotein found in the cell wall of various types of bacteria. It has adjuvant and antitumor act...

Cellular Apoptosis Susceptibility Protein - A nucleocytoplasmic transport protein that binds to ALPHA KARYOPHERINS and RAN GTP BINDING PROTEIN i...

Centromere Protein B - A DNA-binding protein that interacts with a 17-base pair sequence known as the CENP-B box motif. The...

Cerebrospinal Fluid Proteins - Proteins in the cerebrospinal fluid, normally albumin and globulin present in the ratio of 8 to 1. I...

Chaperonin 10 - A group I chaperonin protein that forms a lid-like structure which encloses the non-polar cavity of ...

Chaperonin 60 - A group I chaperonin protein that forms the barrel-like structure of the chaperonin complex. It is a...

Chaperonin Containing TCP-1 - A group II chaperonin found in eukaryotic CYTOSOL. It is comprised of eight subunits with each subun...

Chaperonins - A family of multisubunit protein complexes that form into large cylindrical structures which bind to...

Chemokine CCL1 - A CC-type chemokine secreted by activated MONOCYTES and T-LYMPHOCYTES. It has specificity for CCR8 R...

Chemokine CCL11 - A CC-type chemokine that is specific for CCR3 RECEPTORS. It is a potent chemoattractant for EOSINOPH...

Chemokine CCL17 - A CC-type chemokine that is found at high levels in the THYMUS and has specificity for CCR4 RECEPTOR...

Chemokine CCL19 - A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards T LYMPHOCYTES and B...

Chemokine CCL2 - A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specif...

Chemokine CCL20 - A CC-type chemokine with specificity for CCR6 RECEPTORS. It has activity towards DENDRITIC CELLS; T-...

Chemokine CCL21 - A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards DENDRITIC CELLS and...

Chemokine CCL22 - A CC-type chemokine with specificity for CCR4 RECEPTORS. It has activity towards TH2 CELLS and TC2 C...

Chemokine CCL24 - A CC-type chemokine with specificity for CCR3 RECEPTORS. It is a chemoattractant for EOSINOPHILS....

Chemokine CCL27 - A CC-type chemokine with specificity for CCR10 RECEPTORS. It is constitutively expressed in the skin...

Chemokine CCL3 - A CC chemokine with specificity for CCR1 RECEPTORS and CCR5 RECEPTORS. It is a chemoattractant for N...

Chemokine CCL4 - A CC chemokine with specificity for CCR5 RECEPTORS. It is a chemoattractant for NK CELLS; MONOCYTES ...

Chemokine CCL5 - A CC-type chemokine that is a chemoattractant for EOSINOPHILS; MONOCYTES; and LYMPHOCYTES. It is a p...

Chemokine CCL7 - A monocyte chemoattractant protein that has activity towards a broad variety of immune cell types. C...

Chemokine CCL8 - A monocyte chemoattractant protein that attracts MONOCYTES; LYMPHOCYTES; BASOPHILS; and EOSINOPHILS....

Chemokine CX3CL1 - A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of ...

Chemokine CXCL1 - A CXC chemokine with specificity for CXCR2 RECEPTORS. It has growth factor activities and is implica...

Chemokine CXCL10 - A CXC chemokine that is induced by GAMMA-INTERFERON and is chemotactic for MONOCYTES and T-LYMPHOCYT...

Chemokine CXCL11 - A CXC chemokine that is induced by GAMMA-INTERFERON. It is a chemotactic factor for activated T-LYMP...

Chemokine CXCL12 - A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RE...

Chemokine CXCL13 - A CXC chemokine that is chemotactic for B-LYMPHOCYTES. It has specificity for CXCR5 RECEPTORS....

Chemokine CXCL2 - A CXC chemokine that is synthesized by activated MONOCYTES and NEUTROPHILS. It has specificity for C...

Chemokine CXCL5 - A CXC chemokine that is predominantly expressed in EPITHELIAL CELLS. It has specificity for the CXCR...

Chemokine CXCL6 - A CXC chemokine that has stimulatory and chemotactic activities towards NEUTROPHILS. It has specific...

Chemokine CXCL9 - An INTEFERON-inducible CXC chemokine that is specific for the CXCR3 RECEPTOR....

Chemokines - Class of pro-inflammatory cytokines that have the ability to attract and activate leukocytes. They c...

Chemokines, C - Group of chemokines without adjacent cysteines that are chemoattractants for lymphocytes only....

Chemokines, CC - Group of chemokines with adjacent cysteines that are chemoattractants for lymphocytes, monocytes, eo...

Chemokines, CX3C - Group of chemokines with the first two cysteines separated by three amino acids. CX3C chemokines are...

Chemokines, CXC - Group of chemokines with paired cysteines separated by a different amino acid. CXC chemokines are ch...

Chimerin 1 - A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily...

Chimerin Proteins - A family of GTPASE-ACTIVATING PROTEINS that are specific for RAC GTP-BINDING PROTEINS....

Chloride Channels - Cell membrane glycoproteins that form channels to selectively pass chloride ions. Nonselective block...

Chloride-Bicarbonate Antiporters - Membrane proteins that allow the exchange of chloride ions for bicarbonate ions across the cellular ...

Chloroplast Proton-Translocating ATPases - Proton-translocating ATPases which produce ADENOSINE TRIPHOSPHATE in plants. They derive energy from...

Chloroplast Thioredoxins - A subtype of thioredoxins found primarily in CHLOROPLASTS....

Cholecystokinin - A peptide, of about 33 amino acids, secreted by the upper INTESTINAL MUCOSA and also found in the ce...

Cholesterol 7-alpha-Hydroxylase - A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in t...

Cholesterol Ester Transfer Proteins - Proteins that bind to and transfer CHOLESTEROL ESTERS between LIPOPROTEINS such as LOW-DENSITY LIPOP...

Cholesterol Side-Chain Cleavage Enzyme - A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to ...

Cholesterol, HDL - Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL...

Cholesterol, LDL - Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ...

Cholesterol, VLDL - Cholesterol which is contained in or bound to very low density lipoproteins (VLDL). High circulating...

Chorionic Gonadotropin - A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUT...

Chorionic Gonadotropin, beta Subunit, Human - The beta subunit of human CHORIONIC GONADOTROPIN. Its structure is similar to the beta subunit of LU...

Chromatin - The material of CHROMOSOMES. It is a complex of DNA; HISTONES; and nonhistone proteins (CHROMOSOMAL ...

Chromatin Assembly Factor-1 - A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized ...

Chromogranin A - A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is ...

Chromogranin B - A type of chromogranin which was initially characterized in a rat PHEOCHROMOCYTOMA CELL LINE. It is ...

Chromogranins - A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neur...

Chromosomal Proteins, Non-Histone - Nucleoproteins, which in contrast to HISTONES, are acid insoluble. They are involved in chromosomal ...

Chylomicron Remnants - Metabolic products of chylomicron particles in which TRIGLYCERIDES have been selectively removed by ...

Chylomicrons - A class of lipoproteins that carry dietary CHOLESTEROL and TRIGLYCERIDES from the SMALL INTESTINE to...

Ciliary Neurotrophic Factor - A neurotrophic factor that promotes the survival of various neuronal cell types and may play an impo...

Ciliary Neurotrophic Factor Receptor alpha Subunit - A ciliary neurotrophic factor receptor subunit. It is anchored to the cell surface via GLYCOSYLPHOSP...

Circadian Rhythm Signaling Peptides and Proteins - A broad category of proteins that regulate the CIRCADIAN RHYTHM of an organism. Included here are pr...

Clathrin - The main structural coat protein of COATED VESICLES which play a key role in the intracellular trans...

Clathrin Heavy Chains - The heavy chain subunits of clathrin....

Clathrin Light Chains - The light chain subunits of clathrin....

Claudins - A large family of transmembrane proteins found in TIGHT JUNCTIONS. They take part in the formation o...

Cleavage And Polyadenylation Specificity Factor - An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains fo...

Cleavage Stimulation Factor - A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION si...

Cloacin - A bacteriocin produced by a plasmid that can occur in several bacterial strains. It is a basic prote...

CLOCK Proteins - Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSF...

Clusterin - A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe ph...

Coagulase - Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are...

Coat Protein Complex I - A protein complex comprised of COATOMER PROTEIN and ADP RIBOSYLATION FACTOR 1. It is involved in tra...

Coatomer Protein - A 700-kDa cytosolic protein complex consisting of seven equimolar subunits (alpha, beta, beta', gamm...

Cobra Cardiotoxin Proteins - Most abundant proteins in COBRA venom; basic polypeptides of 57 to 62 amino acids with four disulfid...

Cobra Neurotoxin Proteins - Toxins, contained in cobra (Naja) venom that block cholinergic receptors; two specific proteins have...

Cofilin 1 - Cofilin 1 is a member of the cofilin family of proteins that is expressed in non-muscle CELLS. It ha...

Cofilin 2 - A member of the cofilin family of proteins that is expressed in MUSCLE CELLS. It has ACTIN depolyme...

Colicins - Bacteriocins elaborated by strains of Escherichia coli and related species. They are proteins or pro...

Colipases - Colipase I and II, consisting of 94-95 and 84-85 amino acid residues, respectively, have been isolat...

Colistin - Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or C...

Collagen - A polypeptide substance comprising about one third of the total protein in mammalian organisms. It i...

Collagen Type I - The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and S...

Collagen Type II - A fibrillar collagen found predominantly in CARTILAGE and vitreous humor. It consists of three ident...

Collagen Type III - A fibrillar collagen consisting of three identical alpha1(III) chains that is widely distributed in ...

Collagen Type IV - A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules ass...

Collagen Type IX - A fibril-associated collagen usually found crosslinked to the surface of COLLAGEN TYPE II fibrils. ...

Collagen Type V - A fibrillar collagen found widely distributed as a minor component in tissues that contain COLLAGEN ...

Collagen Type VI - A non-fibrillar collagen that forms a network of MICROFIBRILS within the EXTRACELLULAR MATRIX of CON...

Collagen Type VII - A non-fibrillar collagen involved in anchoring the epidermal BASEMENT MEMBRANE to underlying tissue....

Collagen Type VIII - A non-fibrillar collagen originally found in DESCEMET MEMBRANE. It is expressed in endothelial cell ...

Collagen Type X - A non-fibrillar collagen found primarily in terminally differentiated hypertrophic CHONDROCYTES. It ...

Collagen Type XI - A fibrillar collagen found primarily in interstitial CARTILAGE. Collagen type XI is heterotrimer con...

Collagen Type XII - A fibril-associated collagen found in many tissues bearing high tensile stress, such as TENDONS and ...

Collagen Type XIII - A non-fibrillar collagen found as a ubiquitously expressed membrane- associated protein. Type XIII c...

Collagen Type XVIII - A non-fibrillar collagen found in BASEMENT MEMBRANE. The C-terminal end of the alpha1 chain of colla...

Collectins - A class of C-type lectins that target the carbohydrate structures found on invading pathogens. Bindi...

Colony-Stimulating Factors - Glycoproteins found in a subfraction of normal mammalian plasma and urine. They stimulate the prolif...

Colony-Stimulating Factors, Recombinant - COLONY-STIMULATING FACTORS prepared by recombinant DNA technology....

Complement Activating Enzymes - Enzymes that activate one or more COMPLEMENT PROTEINS in the complement system leading to the format...

Complement C1 - The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a cal...

Complement C1 Inactivator Proteins - Serum proteins that inhibit, antagonize, or inactivate COMPLEMENT C1 or its subunits....

Complement C1 Inhibitor Protein - An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits...

Complement C1q - A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), e...

Complement C1r - A 80-kDa subcomponent of complement C1, existing as a SERINE PROTEASE proenzyme in the intact comple...

Complement C1s - A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proe...

Complement C2 - A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMP...

Complement C2a - The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S. It i...

Complement C2b - The N-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S....

Complement C3 - A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIV...

Complement C3 Convertase, Alternative Pathway - A serine protease that is the complex of COMPLEMENT C3B and COMPLEMENT FACTOR BB. It cleaves multipl...

Complement C3 Convertase, Classical Pathway - A serine protease that cleaves multiple COMPLEMENT 3 into COMPLEMENT 3A (anaphylatoxin) and COMPLEME...

Complement C3 Nephritic Factor - An IgG autoantibody against the ALTERNATIVE PATHWAY C3 CONVERTASE, found in serum of patients with M...

Complement C3a - The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino ...

Complement C3b - The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constitu...

Complement C3b Inactivator Proteins - Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and ...

Complement C3c - A 206-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactiva...

Complement C3-C5 Convertases - Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEM...

Complement C3-C5 Convertases, Alternative Pathway - Important enzymes in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. They cleave COMPLEMENT C3 and CO...

Complement C3-C5 Convertases, Classical Pathway - Important enzymes in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. They cleave COMPLEMENT C3 and COMP...

Complement C3d - A 302-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactiva...

Complement C4 - A glycoprotein that is important in the activation of CLASSICAL COMPLEMENT PATHWAY. C4 is cleaved by...

Complement C4a - The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin ...

Complement C4b - The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b bi...

Complement C4b-Binding Protein - A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor t...

Complement C5 - C5 plays a central role in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. ...

Complement C5 Convertase, Alternative Pathway - A serine protease that cleaves multiple COMPLEMENT C5 into COMPLEMENT C5A (anaphylatoxin) and COMPLE...

Complement C5 Convertase, Classical Pathway - A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEME...

Complement C5a - The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-ami...

Complement C5a, des-Arginine - A derivative of complement C5a, generated when the carboxy-terminal ARGININE is removed by CARBOXYPE...

Complement C5b - The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A a...

Complement C6 - A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C...

Complement C7 - A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges....

Complement C8 - A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; ...

Complement C9 - A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C...

Complement Factor B - A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERN...

Complement Factor D - A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cle...

Complement Factor H - An important soluble regulator of the alternative pathway of complement activation (COMPLEMENT ACTIV...

Complement Factor I - A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofac...

Complement Inactivator Proteins - Serum proteins that negatively regulate the cascade process of COMPLEMENT ACTIVATION. Uncontrolled c...

Complement Membrane Attack Complex - A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane cha...

Complement System Proteins - Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that create...

Complementarity Determining Regions - Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION tha...

Conalbumin - A glycoprotein albumin from hen's egg white with strong iron-binding affinity....

Concanavalin A - A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent ...

Cone Opsins - Photosensitive proteins expressed in the CONE PHOTORECEPTOR CELLS. They are the protein components o...

Connective Tissue Growth Factor - A CCN protein family member that regulates a variety of extracellular functions including CELL ADHES...

Connexin 43 - A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a...

Connexins - A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins...

Contractile Proteins - Proteins which participate in contractile processes. They include MUSCLE PROTEINS as well as those f...

Core Binding Factor Alpha 1 Subunit - A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding fac...

Core Binding Factor Alpha 2 Subunit - A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form cor...

Core Binding Factor Alpha 3 Subunit - A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form cor...

Core Binding Factor alpha Subunits - A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form...

Core Binding Factor beta Subunit - A non-DNA binding transcription factor that is a subunit of core binding factor. It forms heterodime...

Core Binding Factors - Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR AL...

Co-Repressor Proteins - A subclass of repressor proteins that do not directly bind DNA. Instead, co-repressors generally act...

Cornified Envelope Proline-Rich Proteins - A family of low molcular-weight proteins that contain PROLINE-RICH PROTEIN DOMAINS. Members of this ...

Cortactin - A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organi...

Corticotropin-Like Intermediate Lobe Peptide - A peptide derived from the cleavage of ADRENOCORTICOTROPIC HORMONE, found primarily in the INTERMEDI...

Corticotropin-Releasing Hormone - A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is...

Cosyntropin - A synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of ADRENOCORTIC...

COUP Transcription Factor I - A COUP transcription factor that was originally identified as a homodimer that binds to a direct rep...

COUP Transcription Factor II - A COUP transcription factor that negatively regulates GENETIC TRANSCRIPTION and competes with other ...

COUP Transcription Factors - A sub-family of steroid receptor-related orphan nuclear receptors that have specificity for a variet...

CRADD Signaling Adaptor Protein - A death domain receptor signaling adaptor protein that plays a role in signaling the activation of I...

C-Reactive Protein - A plasma protein that circulates in increased amounts during inflammation and after tissue damage....

Crk-Associated Substrate Protein - Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that a...

Cryoglobulins - Abnormal immunoglobulins, especially IGG or IGM, that precipitate spontaneously when SERUM is cooled...

Cryptochromes - Flavoproteins that function as circadian rhythm signaling proteins in ANIMALS and as blue-light phot...

Crystallins - A heterogeneous family of water-soluble structural proteins found in cells of the vertebrate lens. T...

Cullin Proteins - A family of structurally related proteins that were originally discovered for their role in cell-cyc...

Cyclic AMP Receptor Protein - A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at seve...

Cyclic AMP Response Element Modulator - Cyclic AMP response element modulator is a basic leucine zipper transcription factor that is regulat...

Cyclic AMP Response Element-Binding Protein - A protein that has been shown to function as a calcium-regulated transcription factor as well as a s...

Cyclic AMP Response Element-Binding Protein A - A basic leucine zipper transcription factor that is highly homologous to ACTIVATING TRANSCRIPTION FA...

Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - Specific enzyme subunits that form the active sites of the type I and type II cyclic-AMP protein kin...

Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - A type I cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP ...

Cyclic AMP-Dependent Protein Kinase RIbeta Subunit - A type I cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP ...

Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit - A type II cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP...

Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - A type II cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP...

Cyclic AMP-Dependent Protein Kinase Type I - A cyclic AMP-dependent protein kinase subtype primarily found in the CYTOPLASM. They are tetrameric ...

Cyclic AMP-Dependent Protein Kinase Type II - A cyclic AMP-dependent protein kinase subtype primarily found in particulate subcellular fractions. ...

Cyclic AMP-Dependent Protein Kinases - A group of enzymes that are dependent on CYCLIC AMP and catalyze the phosphorylation of SERINE or TH...

Cyclic GMP-Dependent Protein Kinases - A group of enzymes that are dependent on cyclic GMP and catalyzes the phosphorylation of serine or t...

Cyclic Nucleotide Phosphodiesterases, Type 1 - A CALCIUM and CALMODULIN-dependent cyclic nucleotide phosphodiesterase subfamily. The three members ...

Cyclic Nucleotide Phosphodiesterases, Type 2 - A cyclic nucleotide phosphodiesterase subfamily that is activated by the binding of CYCLIC GMP to an...

Cyclic Nucleotide Phosphodiesterases, Type 3 - A cyclic nucleotide phosphodiesterase subfamily that is inhibited by the binding of CYCLIC GMP to an...

Cyclic Nucleotide Phosphodiesterases, Type 4 - A cyclic nucleotide phosphodiesterase subfamily that is found predominantly in inflammatory cells an...

Cyclic Nucleotide Phosphodiesterases, Type 5 - A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found ...

Cyclic Nucleotide Phosphodiesterases, Type 6 - A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found ...

Cyclic Nucleotide Phosphodiesterases, Type 7 - A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC AMP. Several isof...

Cyclic Nucleotide-Gated Cation Channels - Ion channels that are regulated by cyclic GMP or cyclic AMP binding and contain six transmembrane se...

Cyclic Nucleotide-Regulated Protein Kinases - A group of enzymes that catalyzes the phosphorylation of serine or threonine residues of proteins an...

Cyclin A - A cyclin subtype that has specificity for CDC2 PROTEIN KINASE and CYCLIN-DEPENDENT KINASE 2. It play...

Cyclin A1 - A cyclin A subtype primarily found in male GERM CELLS. It may play a role in the passage of SPERMATO...

Cyclin A2 - A widely-expressed cyclin A subtype that functions during the G1/S and G2/M transitions of the CELL ...

Cyclin B - A cyclin subtype that is transported into the CELL NUCLEUS at the end of the G2 PHASE. It stimulates...

Cyclin B1 - A cyclin B subtype that colocalizes with MICROTUBULES during INTERPHASE and is transported into the ...

Cyclin B2 - A cyclin B subtype that colocalizes with GOLGI APPARATUS during INTERPHASE and is transported into t...

Cyclin C - A cyclin subtype that binds to the CYCLIN-DEPENDENT KINASE 3 and CYCLIN-DEPENDENT KINASE 8. Cyclin C...

Cyclin D - A cyclin subtype that is specific for CYCLIN-DEPENDENT KINASE 4 and CYCLIN-DEPENDENT KINASE 6. Unlik...

Cyclin D1 - Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpr...

Cyclin D2 - A cyclin D subtype which is regulated by GATA4 TRANSCRIPTION FACTOR. Experiments using KNOCKOUT MICE...

Cyclin D3 - A broadly expressed type D cyclin. Experiments using KNOCKOUT MICE suggest a role for cyclin D3 in L...

Cyclin E - A 50-kDa protein that complexes with CYCLIN-DEPENDENT KINASE 2 in the late G1 phase of the cell cycl...

Cyclin G - A cyclin subtype that is found associated with CYCLIN-DEPENDENT KINASE 5; cyclin G associated kinase...

Cyclin G1 - A cyclin G subtype that is constitutively expressed throughout the cell cycle. Cyclin G1 is consider...

Cyclin G2 - An unusual cyclin subtype that is found highly expressed in terminally differentiated cells. Unlike ...

Cyclin H - A cyclin subtype that is found as a component of a heterotrimeric complex containing cyclin-dependen...

Cyclin I - A cyclin subtype that is found abundantly in post-mitotic tissues. In contrast to the classical cycl...

Cyclin T - A cyclin subtype that is found associated with CYCLIN-DEPENDENT KINASE 9. Unlike traditional cyclins...

Cyclin-Dependent Kinase 2 - A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE ...

Cyclin-Dependent Kinase 3 - A cyclin-dependent kinase that forms a complex with CYCLIN C and is active during the G1 PHASE of th...

Cyclin-Dependent Kinase 4 - Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN ...

Cyclin-Dependent Kinase 5 - A serine-threonine kinase that plays important roles in CELL DIFFERENTIATION; CELL MIGRATION; and CE...

Cyclin-Dependent Kinase 6 - Cyclin-dependent kinase 6 associates with CYCLIN D and phosphorylates RETINOBLASTOMA PROTEIN during ...

Cyclin-Dependent Kinase 8 - A CYCLIN C dependent kinase that is an important component of the mediator complex. The enzyme is ac...

Cyclin-Dependent Kinase 9 - A multifunctional CDC2 kinase-related kinase that plays roles in transcriptional elongation, CELL DI...

Cyclin-Dependent Kinase Inhibitor p15 - An INK4 cyclin-dependent kinase inhibitor containing four ANKYRIN-LIKE REPEATS. INK4B is often inact...

Cyclin-Dependent Kinase Inhibitor p16 - A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it ...

Cyclin-Dependent Kinase Inhibitor p18 - An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN-LIKE REPEATS. Aberrant expression ...

Cyclin-Dependent Kinase Inhibitor p19 - An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN REPEATS. Aberrant expression of th...

Cyclin-Dependent Kinase Inhibitor p21 - A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE ...

Cyclin-Dependent Kinase Inhibitor p27 - A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT K...

Cyclin-Dependent Kinase Inhibitor p57 - A potent inhibitor of CYCLIN-DEPENDENT KINASES in G1 PHASE and S PHASE. In humans, aberrant expressi...

Cyclin-Dependent Kinase Inhibitor Proteins - A group of cell cycle proteins that negatively regulate the activity of CYCLIN/CYCLIN-DEPENDENT KINA...

Cyclin-Dependent Kinases - Protein kinases that control cell cycle progression in all eukaryotes and require physical associati...

Cyclins - A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEP...

Cyclophilins - A family of peptidyl-prolyl cis-trans isomerases that bind to CYCLOSPORINS and regulate the IMMUNE S...

Cystatin A - A cytastin subtype found at high levels in the SKIN and in BLOOD CELLS. Cystatin A incorporates into...

Cystatin B - An intracellular cystatin subtype that is found in a broad variety of cell types. It is a cytosolic ...

Cystatin C - An extracellular cystatin subtype that is abundantly expressed in bodily fluids. It may play a role ...

Cystatin M - A cystatin subtype that has a diverse tissue distribution, target specificity, and functions as an e...

Cystatins - A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE...

Cysteine-Rich Protein 61 - A CCN protein family member that regulates a variety of extracellular functions including CELL ADHES...

Cystic Fibrosis Transmembrane Conductance Regulator - A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene...

Cytochrome a Group - Cytochromes (electron-transporting proteins) in which the heme prosthetic group is heme a, i.e., the...

Cytochrome b Group - Cytochromes (electron-transporting proteins) with protoheme (HEME B) as the prosthetic group....

Cytochrome b6f Complex - A protein complex that includes CYTOCHROME B6 and CYTOCHROME F. It is found in the THYLAKOID MEMBRAN...

Cytochrome c Group - A group of cytochromes with covalent thioether linkages between either or both of the vinyl side cha...

Cytochrome d Group - Cytochromes (electron-transporting proteins) with a tetrapyrrolic chelate of iron as a prosthetic gr...

Cytochrome P-450 CYP1A1 - A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as pol...

Cytochrome P-450 CYP1A2 - A cytochrome P-450 monooxygenase that can be induced by polycyclic aromatic xenobiotics in the liver...

Cytochrome P-450 CYP27A1 - An NAPH-dependent cytochrome P450 enzyme that catalyzes the oxidation of the side chain of sterol in...

Cytochrome P-450 CYP2B1 - A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTE...

Cytochrome P-450 CYP2D6 - A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals,...

Cytochrome P-450 CYP2E1 - An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solv...

Cytochrome P-450 CYP3A - A cytochrome P-450 monooxygenase that is involved in an NADPH-dependent electron transport pathway b...

Cytochrome P-450 Enzyme System - A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum...

Cytochrome-B(5) Reductase - A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due t...

Cytochromes - Hemeproteins whose characteristic mode of action involves transfer of reducing equivalents which are...

Cytochromes a - A subclass of heme a containing cytochromes that have two imidazole nitrogens as axial ligands and a...

Cytochromes a1 - A subclass of heme a containing cytochromes have a reduced alpha-band absorption of 587-592 nm. They...

Cytochromes a3 - A subclass of heme a containing cytochromes with an alpha-band absorption of 605 nm. They are found ...

Cytochromes b - Cytochromes of the b group that have alpha-band absorption of 563-564 nm. They occur as subunits in ...

Cytochromes b5 - Cytochromes of the b group that are found bound to cytoplasmic side of ENDOPLASMIC RETICULUM. They s...

Cytochromes b6 - Cytochromes of the b group that are found as components of the CYTOCHROME B6F COMPLEX. They contain ...

Cytochromes c - Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediat...

Cytochromes c' - A widely occurring subclass of c type cytochromes which function as electron carriers in the electro...

Cytochromes c1 - The 30-kDa membrane-bound c-type cytochrome protein of mitochondria that functions as an electron do...

Cytochromes c2 - Type C cytochromes that are small (12-14 kD) single-heme proteins. They function as mobile electron ...

Cytochromes c6 - Cytochromes of the c type that are involved in the transfer of electrons from CYTOCHROME B6F COMPLEX...

Cytochromes f - Cytochromes f are found as components of the CYTOCHROME B6F COMPLEX. They play important role in the...

Cytokine Receptor Common beta Subunit - A receptor subunit that is a shared component of the INTERLEUKIN-3 RECEPTOR; the INTERLEUKIN-5 RECEP...

Cytokine Receptor gp130 - A cytokine receptor that acts through the formation of oligomeric complexes of itself with a variety...

Cytokines - Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as...

Cytoskeletal Proteins - Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexib...

DAX-1 Orphan Nuclear Receptor - An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike ...

DEAD Box Protein 20 - A multifunctional protein that is both a DEAD-box RNA helicase and a component of the SMN protein c...

Deamino Arginine Vasopressin - A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VAS...

Death Domain Receptor Signaling Adaptor Proteins - Intracellular signaling adaptor proteins that bind to the cytoplasmic death domain region found on D...

Defensins - Family of antimicrobial peptides that have been identified in humans, animals, and plants. They are ...

DEFICIENS Protein - DEFICIENS is a homeotic gene involved in the genetic control of Antirrhinum majus flower development...

Delayed Rectifier Potassium Channels - A group of slow opening and closing voltage-gated potassium channels. Because of their delayed activ...

Delta Sleep-Inducing Peptide - A nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mai...

delta-Crystallins - A subclass of crystallins found in the lens (LENS, CRYSTALLINE) in BIRDS and REPTILES. They are inac...

delta-Globins - A member of the beta-globin family. In humans, delta-globin is encoded in the beta-globin gene clust...

Deltaretrovirus Antibodies - Antibodies reactive with various types of human T-cell leukemia/lymphoma antigens or bovine leukemia...

Dental Enamel Proteins - The proteins that are part of the dental enamel matrix....

Deoxyribonucleoproteins - Proteins conjugated with deoxyribonucleic acids (DNA) or specific DNA....

Dermcidins - 47-amino acid peptides secreted by ECCRINE GLANDS and having a role in innate cutaneous defense, bei...

Desmin - An intermediate filament protein found predominantly in smooth, skeletal, and cardiac muscle cells. ...

Desmocollins - A group of desmosomal cadherins with cytoplasmic tails that are divergent from those of classical CA...

Desmoglein 1 - A desmosomal cadherin that is an autoantigen in the acquired skin disorder PEMPHIGUS FOLIACEUS....

Desmoglein 2 - A CALCIUM-dependent adhesion molecule of DESMOSOMES that also plays a role in embryonic STEM CELL pr...

Desmoglein 3 - A desmosomal cadherin that is an autoantigen in the acquired skin disorder PEMPHIGUS VULGARIS....

Desmogleins - A group of desmosomal cadherins with cytoplasmic tails that resemble those of classical CADHERINS....

Desmoplakins - Desmoplakins are cytoskeletal linker proteins that anchor INTERMEDIATE FILAMENTS to the PLASMA MEMBR...

Desmosomal Cadherins - A single-pass transmembrane glycoproteins that mediate CALCIUM-dependent CELL ADHESION and are core ...

Destrin - A member of the actin depolymerizing factors. Its depolymerizing activity is independent of HYDROGEN...

Dicarboxylic Acid Transporters - A family of organic anion transporters that specifically transport DICARBOXYLIC ACIDS such as alpha-...

Dietary Proteins - Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS....

Dihydrolipoamide Dehydrogenase - A flavoprotein containing oxidoreductase that catalyzes the reduction of lipoamide by NADH to yield ...

Diphtheria Antitoxin - An antitoxin produced against the toxin of CORYNEBACTERIUM DIPHTHERIAE that is used for the treatmen...

DNA Topoisomerases, Type I, Archaeal - Archaeal enzymes of the DNA TOPOISOMERASES, TYPE I class that catalyze ATP-independent breakage of o...

DNA-Binding Proteins - Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stran...

Dopamine and cAMP-Regulated Phosphoprotein 32 - A phosphoprotein that was initially identified as a major target of DOPAMINE activated ADENYLYL CYCL...

Dopamine Plasma Membrane Transport Proteins - Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of do...

Drosophila Proteins - Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the...

Dual Specificity Phosphatase 1 - A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by ina...

Dual Specificity Phosphatase 2 - A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by ina...

Dual Specificity Phosphatase 3 - A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by ina...

Dual Specificity Phosphatase 6 - A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by ina...

Dual-Specificity Phosphatases - A sub-class of protein tyrosine phosphatases that contain an additional phosphatase activity which c...

Dynamin I - A subtype of dynamin found primarily in the NEURONS of the brain....

Dynamin II - A subtype of dynamin found ubiquitously expressed in a variety of tissues....

Dynamin III - A subtype of dynamin found expressed exclusively in the testis, lung and brain....

Dynamins - A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport...

Dyneins - A family of multisubunit cytoskeletal motor proteins that use the energy of ATP hydrolysis to power ...

Dynorphins - A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptid...

Dystroglycans - Dystrophin-associated proteins that play role in the formation of a transmembrane link between lamin...

Dystrophin - A muscle protein localized in surface membranes which is the product of the Duchenne/Becker muscular...

Dystrophin-Associated Proteins - A group of proteins that associate with DYSTROPHIN at the CELL MEMBRANE to form the DYSTROPHIN-ASSOC...

E1A-Associated p300 Protein - A member of the p300-CBP transcription factors that was originally identified as a binding partner f...

E2F Transcription Factors - A family of basic helix-loop-helix transcription factors that control expression of a variety of GEN...

E2F1 Transcription Factor - An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A and act...

E2F2 Transcription Factor - An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F2 a...

E2F3 Transcription Factor - An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F3 ...

E2F4 Transcription Factor - An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and D...

E2F5 Transcription Factor - An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and D...

E2F6 Transcription Factor - An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and D...

E2F7 Transcription Factor - An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and D...

Early Growth Response Protein 1 - An early growth response transcription factor that has been implicated in regulation of CELL PROLIFE...

Early Growth Response Protein 2 - An early growth response transcription factor that controls the formation of the MYELIN SHEATH aroun...

Early Growth Response Protein 3 - An early growth response transcription factor that is essential for the development of MUSCLE SPINDL...

Early Growth Response Transcription Factors - A family of transcription factors that are induced by GROWTH FACTORS and contain a highly conserved ...

Ectodysplasins - Transmembrane proteins belonging to the tumor necrosis factor superfamily that play an essential rol...

Edar Receptor - A ectodysplasin receptor subtype that is specific for ECTODYSPLASIN A1. It signals via the specific ...

Edar-Associated Death Domain Protein - A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein...

Egg Proteins - Proteins which are found in eggs (OVA) from any species....

Egg Proteins, Dietary - Proteins found in eggs which are consumed as a food....

eIF-2 Kinase - A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In...

Elafin - A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found i...

Electron Transport Complex I - A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UB...

Electron Transport Complex II - A flavoprotein oxidase complex that contains iron-sulfur centers. It catalyzes the oxidation of SUCC...

Electron Transport Complex III - A multisubunit enzyme complex that contains CYTOCHROME B GROUP; CYTOCHROME C1; and iron-sulfur cente...

Electron Transport Complex IV - A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13...

Electron-Transferring Flavoproteins - Flavoproteins that serve as specific electron acceptors for a variety of DEHYDROGENASES. They partic...

Eledoisin - A peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollus...

Elongation Factor 2 Kinase - A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEP...

Endorphins - One of the three major groups of endogenous opioid peptides. They are large peptides derived from th...

Endosomal Sorting Complexes Required for Transport - A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intralumina...

Endostatins - Angiostatic proteins that are formed from proteolytic cleavage of COLLAGEN TYPE XVIII....

Endothelial Growth Factors - These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture...

Endothelin-1 - A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-m...

Endothelin-2 - A 21-amino acid peptide produced predominantly within the kidney and intestine, with smaller amounts...

Endothelin-3 - A 21-amino acid peptide that circulates in the plasma, but its source is not known. Endothelin-3 has...

Endothelins - 21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstric...

Enkephalin, Ala(2)-MePhe(4)-Gly(5)- - An enkephalin analog that selectively binds to the MU OPIOID RECEPTOR. It is used as a model for dru...

Enkephalin, D-Penicillamine (2,5)- - A disulfide opioid pentapeptide that selectively binds to the DELTA OPIOID RECEPTOR. It possesses an...

Enkephalin, Leucine - One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in t...

Enkephalin, Methionine - One of the endogenous pentapeptides with morphine-like activity. It differs from LEU-ENKEPHALIN by t...

Enkephalins - One of the three major families of endogenous opioid peptides. The enkephalins are pentapeptides tha...

env Gene Products, Human Immunodeficiency Virus - Proteins encoded by the ENV GENE of the HUMAN IMMUNODEFICIENCY VIRUS....

Enzymes, Immobilized - Enzymes which are immobilized on or in a variety of water-soluble or water-insoluble matrices with l...

Eosinophil Cationic Protein - One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil cationic pro...

Eosinophil Granule Proteins - Proteins found in EOSINOPHIL granules. They are primarily basic proteins that play a role in host de...

Eosinophil Major Basic Protein - One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil major basic ...

Eosinophil Peroxidase - A 66-kDa peroxidase found in EOSINOPHIL granules. Eosinophil peroxidase is a cationic protein with a...

Eosinophil-Derived Neurotoxin - A 19-kDa cationic peptide found in EOSINOPHIL granules. Eosinophil-derived neurotoxin is a RIBONUCLE...

Ephrin-A1 - An ephrin that was originally identified as the product of an early response gene induced by TUMOR N...

Ephrin-A2 - A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR-containing ephrin with a high affinity for the EPHA3 RE...

Ephrin-A3 - A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin with a high affinity for the EPHA3 RE...

Ephrin-A4 - A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in variety of adult tissue such...

Ephrin-A5 - A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It has be...

Ephrin-B1 - A transmembrane domain containing ephrin that is specific for EPHB1 RECEPTOR; EPHB2 RECEPTOR and EPH...

Ephrin-B2 - A transmembrane domain containing ephrin that binds with high affinity to EPHB1 RECEPTOR; EPHB3 RECE...

Ephrin-B3 - A transmembrane domain containing ephrin. Although originally found to be specific for the EPHB3 REC...

Ephrins - Signaling proteins that are ligands for the EPH FAMILY RECEPTORS. They are membrane-bound proteins t...

Epidermal Growth Factor - A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal...

Epididymal Secretory Proteins - Proteins secreted by the epididymal epithelium. These proteins are both tissue- and species-specific...

Epithelial Sodium Channel - An AMILORIDE-sensitive sodium channel found on salt-reabsorbing EPITHELIAL CELLS that line the dista...

Epoetin Alfa - This recombinant erythropoietin, a 165-amino acid glycoprotein (about 62% protein and 38% carbohydra...

epsilon-Crystallins - A group of crystallins that have been found in the lens (LENS, CRYSTALLINE) of DUCKS and CROCODILES....

epsilon-Globins - A member of the beta-globin family. In humans, epsilon-globin is encoded in the beta-globin gene clu...

Equilibrative Nucleoside Transport Proteins - A class of sodium-independent nucleoside transporters that mediate the facilitative transport of NUC...

Equilibrative Nucleoside Transporter 1 - A subtype of equilibrative nucleoside transporter proteins that is sensitive to inhibition by 4-nitr...

Equilibrative-Nucleoside Transporter 2 - A subtype of equilibrative nucleoside transporter proteins that is insensitive to inhibition by 4-ni...

Erythrocruorins - High molecular weight (1,500,000 to 3,000,000) hemoglobins found in the plasma of many polychete and...

Erythroid-Specific DNA-Binding Factors - A group of transcription factors that were originally described as being specific to ERYTHROID CELLS...

Erythropoietin - Glycoprotein hormone, secreted chiefly by the kidney in the adult and the liver in the fetus, that a...

Erythropoietin, Recombinant - ERYTHROPOIETIN prepared by recombinant DNA technology....

Escherichia coli Proteins - Proteins obtained from ESCHERICHIA COLI....

E-Selectin - Cell adhesion molecule and CD antigen that mediates neutrophil, monocyte, and memory T-cell adhesion...

Estrogen Receptor alpha - One of the ESTROGEN RECEPTORS that has marked affinity for ESTRADIOL. Its expression and function di...

Estrogen Receptor beta - One of the ESTROGEN RECEPTORS that has greater affinity for ISOFLAVONES than ESTROGEN RECEPTOR ALPHA...

Ether-A-Go-Go Potassium Channels - A family of voltage-gated potassium channels that are characterized by long N-terminal and C-termina...

ets-Domain Protein Elk-1 - A member of the ternary complex family of ets-related transcription factors that is regulated by MIT...

ets-Domain Protein Elk-4 - A member of the ternary complex family of ets-related transcription factors that is regulated by MIT...

Euchromatin - Chromosome regions that are loosely packaged and more accessible to RNA polymerases than HETEROCHROM...

Eukaryotic Initiation Factor-1 - A eukaryotic initiation factor that binds to 40S ribosomal subunits. Although initially considered a...

Eukaryotic Initiation Factor-2 - Eukaryotic initiation factor of protein synthesis. In higher eukaryotes the factor consists of three...

Eukaryotic Initiation Factor-2B - A guanine nucleotide exchange factor that acts to restore EUKARYOTIC INITIATION FACTOR-2 to its GTP ...

Eukaryotic Initiation Factor-3 - A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It play...

Eukaryotic Initiation Factor-4A - A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the sec...

Eukaryotic Initiation Factor-4E - A peptide initiation factor that binds specifically to the 5' MRNA CAP STRUCTURE of MRNA in the CYTO...

Eukaryotic Initiation Factor-4F - A trimeric peptide initiation factor complex that associates with the 5' MRNA cap structure of RNA (...

Eukaryotic Initiation Factor-4G - A component of eukaryotic initiation factor-4F that is involved in multiple protein interactions at ...

Eukaryotic Initiation Factor-5 - A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the hydro...

Eukaryotic Initiation Factors - Peptide initiation factors from eukaryotic organisms. Over twelve factors are involved in PEPTIDE ...

Excitatory Amino Acid Transporter 1 - A glial type glutamate plasma membrane transporter protein found predominately in ASTROCYTES. It is ...

Excitatory Amino Acid Transporter 2 - A glutamate plasma membrane transporter protein found in ASTROCYTES and in the LIVER....

Excitatory Amino Acid Transporter 3 - A neuronal and epithelial type glutamate plasma membrane transporter protein....

Excitatory Amino Acid Transporter 4 - A glutamate plasma membrane transporter protein that is primarily expressed in cerebellar PURKINJE C...

Excitatory Amino Acid Transporter 5 - A glutamate plasma membrane transporter protein that is primarily expressed in the RETINA....

Exfoliatins - Protein exotoxins from Staphylococcus aureus, phage type II, which cause epidermal necrolysis. They ...

Extracellular Matrix Proteins - Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfu...

Extracellular Signal-Regulated MAP Kinases - A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation...

Factor For Inversion Stimulation Protein - A highly abundant DNA binding protein whose expression is strongly correlated with the growth phase ...

Factor IX - Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, fo...

Factor IXa - Activated form of factor IX. This activation can take place via the intrinsic pathway by the action ...

Factor V - Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thro...

Factor Va - Activated form of factor V. It is an essential cofactor for the activation of prothrombin catalyzed ...

Factor VII - Heat- and storage-stable plasma protein that is activated by tissue thromboplastin to form factor VI...

Factor VIIa - Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagu...

Factor VIII - Blood-coagulation factor VIII. Antihemophilic factor that is part of the factor VIII/von Willebrand ...

Factor VIIIa - Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to...

Factor X - Storage-stable glycoprotein blood coagulation factor that can be activated to factor Xa by both the ...

Factor Xa - Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood c...

Factor XI - Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates ...

Factor XIa - Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa ...

Factor XII - Stable blood coagulation factor activated by contact with the subendothelial surface of an injured v...

Factor XIIa - Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, ka...

Factor XIII - A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to ...

Factor XIIIa - Activated form of FACTOR XIII, a transglutaminase, which stabilizes the formation of the fibrin poly...

Fanconi Anemia Complementation Group A Protein - A Fanconi anemia complementation group protein that is the most commonly mutated protein in FANCONI ...

Fanconi Anemia Complementation Group C Protein - A Fanconi anemia complementation group protein that regulates the activities of CYTOCHROME P450 REDU...

Fanconi Anemia Complementation Group D2 Protein - A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN i...

Fanconi Anemia Complementation Group E Protein - A Fanconi anemia complementation group protein that interacts with FANCC PROTEIN and FANCD2 PROTEIN....

Fanconi Anemia Complementation Group F Protein - A Fanconi anemia complementation group protein. It is an essential component of a nuclear core compl...

Fanconi Anemia Complementation Group G Protein - A Fanconi anemia complementation group protein that undergoes PHOSPHORYLATION by CDC2 PROTEIN KINASE...

Fanconi Anemia Complementation Group L Protein - An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PR...

Fanconi Anemia Complementation Group Proteins - A diverse group of proteins whose genetic MUTATIONS have been associated with the chromosomal instab...

Fas Ligand Protein - A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally disco...

Fas-Associated Death Domain Protein - A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a deat...

Fatty Acid Transport Proteins - A broad category of membrane transport proteins that specifically transport FREE FATTY ACIDS across ...

Fatty Acid-Binding Proteins - Intracellular proteins that reversibly bind hydrophobic ligands including: saturated and unsaturated...

F-Box Proteins - A family of proteins that share the F-BOX MOTIF and are involved in protein-protein interactions. Th...

Felypressin - A synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vas...

Ferredoxin-Nitrite Reductase - An IRON-containing protein that uses siroheme and 4Fe-4S iron-sulfur centers as prosthetic groups. I...

Ferredoxins - Iron-containing proteins that transfer electrons, usually at a low potential, to flavoproteins; the ...

Ferritins - Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their m...

Fetal Hemoglobin - The major component of hemoglobin in the fetus. This HEMOGLOBIN has two alpha and two gamma polypept...

Fibril-Associated Collagens - A family of non-fibrillar collagens that interact with FIBRILLAR COLLAGENS. They contain short tripl...

Fibrillar Collagens - A family of structurally related collagens that form the characteristic collagen fibril bundles seen...

Fibrin - A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot....

Fibrin Fibrinogen Degradation Products - Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP a...

Fibrin Foam - A dry artificial sterile sponge of fibrin prepared by clotting with thrombin a foam or solution of f...

Fibrin Tissue Adhesive - An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial produ...

Fibrinogen - Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypep...

Fibrinogens, Abnormal - Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in ...

Fibrinopeptide A - Two small peptide chains removed from the N-terminal segment of the alpha chains of fibrinogen by th...

Fibrinopeptide B - Two small peptide chains removed from the N-terminal segment of the beta chains of fibrinogen by the...

Fibroblast Growth Factor 1 - A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUN...

Fibroblast Growth Factor 10 - A fibroblast growth factor that is a mitogen for KERATINOCYTES. It activates FIBROBLAST GROWTH FACTO...

Fibroblast Growth Factor 2 - A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALI...

Fibroblast Growth Factor 3 - A fibroblast growth factor that is expressed primarily during development....

Fibroblast Growth Factor 4 - A HEPARIN binding fibroblast growth factor that may play a role in LIMB BUDS development....

Fibroblast Growth Factor 5 - A fibroblast growth factor that may play a role in regulation of HAIR FOLLICLE phenotype. Spontaneou...

Fibroblast Growth Factor 6 - A fibroblast growth factor that was initially identified based on its sequence similarity to FIBROBL...

Fibroblast Growth Factor 7 - A fibroblast growth factor that is a specific mitogen for EPITHELIAL CELLS. It binds a complex of HE...

Fibroblast Growth Factor 8 - A fibroblast growth factor that preferentially activates FIBROBLAST GROWTH FACTOR RECEPTOR 4. It was...

Fibroblast Growth Factor 9 - A fibroblast growth factor that was originally identified as a mitogen for GLIAL CELLS. It is expres...

Fibroblast Growth Factors - A family of small polypeptide growth factors that share several common features including a strong a...

Fibroins - Fibrous proteins secreted by INSECTS and SPIDERS. Generally, the term refers to silkworm fibroin sec...

Fibronectins - Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are...

Filgrastim - A hematopoietic growth factor which promotes proliferation and maturation of neutrophil granulocytes...

Fimbriae Proteins - Proteins that are structural components of bacterial fimbriae (FIMBRIAE, BACTERIAL) or sex pili (PIL...

Fish Proteins - Proteins obtained from species of fish (FISHES)....

Flagellin - A protein with a molecular weight of 40,000 isolated from bacterial flagella. At appropriate pH and ...

Flavodoxin - A low-molecular-weight (16,000) iron-free flavoprotein containing one molecule of flavin mononucleot...

FMRFamide - A molluscan neuroactive peptide which induces a fast excitatory depolarizing response due to direct ...

fms-Like Tyrosine Kinase 3 - A receptor tyrosine kinase that is involved in HEMATOPOIESIS. It is closely related to FMS PROTO-ONC...

Focal Adhesion Kinase 1 - A non-receptor protein tyrosine kinase that is localized to FOCAL ADHESIONS and is a central compone...

Focal Adhesion Protein-Tyrosine Kinases - A family of non-receptor, PROLINE-rich protein-tyrosine kinases....

Follistatin - A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist...

Follistatin-Related Proteins - Broadly distributed glycoproteins that are homologous to the activin-binding protein, FOLLISTATIN. T...

Forkhead Transcription Factors - A subclass of winged helix DNA-binding proteins that share homology with their founding member fork ...

Fos-Related Antigen-2 - A basic-leucine zipper transcription factor that is closely related to C-FOS PROTEINS. It forms hete...

Fragile X Mental Retardation Protein - A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSL...

Frizzled Receptors - A family of seven-pass transmembrane cell-surface receptors. They contain an extracellular cysteine...

Fungal Proteins - Proteins found in any species of fungus....

Fushi Tarazu Transcription Factors - Fushi tarazu transcription factors were originally identified in DROSOPHILA. They are found througho...

Fusion Proteins, bcr-abl - Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the g...

Fusion Proteins, gag-onc - General name for the translation products of a fusion mRNA consisting of a gag gene and a viral onco...

Fusion Proteins, gag-pol - Polyprotein products of a fused portion of retroviral mRNA containing the gag and pol genes. The pol...

G Protein-Coupled Inwardly-Rectifying Potassium Channels - A family of inwardly-rectifying potassium channels that are activated by PERTUSSIS TOXIN sensitive G...

GABA Plasma Membrane Transport Proteins - A family of plasma membrane neurotransmitter transporter proteins that regulates that extracellular ...

GA-Binding Protein Transcription Factor - A heterotetrameric transcription factor composed of two distinct proteins. Its name refers to the fa...

gag Gene Products, Human Immunodeficiency Virus - Proteins encoded by the GAG GENE of the HUMAN IMMUNODEFICIENCY VIRUS....

Galanin - A neuropeptide of 29-30 amino acids depending on the species. Galanin is widely distributed througho...

Galectin 1 - A galectin found abundantly in smooth muscle (MUSCLE, SMOOTH) and SKELETAL MUSCLE and many other tis...

Galectin 2 - A galectin found preferentially expressed in the gastrointestinal tract. The protein occurs as a ho...

Galectin 3 - A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN...

Galectin 4 - A galectin found in the small and large intestine and the stomach. It occurs as a homodimer with two...

Galectins - A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner...

gamma Catenin - A multi-functional catenin that is highly homologous to BETA CATENIN. Gamma catenin binds CADHERINS...

gamma-Crystallins - A subclass of crystallins that found in the lens (LENS, CRYSTALLINE) of VERTEBRATES. Gamma-crystalli...

gamma-Endorphin - An endogenous opioid peptide derived from BETA-LIPOTROPIN of the pro-opiomelanocortin (POMC) system....

gamma-Globins - Members of the beta-globin family. In humans, two non-allelic types of gamma-globin - A gamma and G ...

gamma-Globulins - Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At ...

gamma-Lipotropin - A lipotropic peptide that is the N-terminal fragment of beta-lipotropin. It is a peptide of 56 amino...

gamma-MSH - An 11-amino acid peptide derived from the N-terminal fragment of pro-opiomelanocortin (POMC). Gamma-...

gamma-Synuclein - A homolog of ALPHA-SYNUCLEIN that plays a role in neurofilament network integrity. It is overexpress...

GAP-43 Protein - A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE ...

Gastric Inhibitory Polypeptide - A gastrointestinal peptide hormone of about 43-amino acids. It is found to be a potent stimulator of...

Gastric Mucins - Mucins that are found on the surface of the gastric epithelium. They play a role in protecting the e...

Gastrin-Releasing Peptide - Neuropeptide and gut hormone that helps regulate GASTRIC ACID secretion and motor function. Once rel...

Gastrins - A family of gastrointestinal peptide hormones that excite the secretion of GASTRIC JUICE. They may a...

GATA Transcription Factors - A family of transcription factors that contain two ZINC FINGER MOTIFS and bind to the DNA sequence (...

GATA1 Transcription Factor - A GATA transcription factor that is specifically expressed in hematopoietic lineages and plays an im...

GATA2 Transcription Factor - An essential GATA transcription factor that is expressed primarily in HEMATOPOIETIC STEM CELLS....

GATA3 Transcription Factor - A GATA transcription factor that is found predominately in LYMPHOID CELL precursors and has been imp...

GATA4 Transcription Factor - A GATA transcription factor that is expressed in the MYOCARDIUM of developing heart and has been imp...

GATA5 Transcription Factor - A GATA transcription factor that is expressed predominately in SMOOTH MUSCLE CELLS and is involved i...

GATA6 Transcription Factor - A GATA transcription factor that is expressed predominately in SMOOTH MUSCLE CELLS and regulates vas...

G-Box Binding Factors - A family of transcription factors found primarily in PLANTS that bind to the G-box DNA sequence CACG...

Gelatin - A product formed from skin, white connective tissue, or bone COLLAGEN. It is used as a protein food ...

Gelsolin - A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly ex...

Gene Products, env - Retroviral proteins, often glycosylated, coded by the envelope (env) gene. They are usually synthesi...

Gene Products, gag - Proteins coded by the retroviral gag gene. The products are usually synthesized as protein precursor...

Gene Products, nef - Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate ...

Gene Products, pol - Retroviral proteins coded by the pol gene. They are usually synthesized as a protein precursor (POLY...

Gene Products, rev - Trans-acting nuclear proteins whose functional expression are required for retroviral replication. S...

Gene Products, rex - Post-transcriptional regulatory proteins required for the accumulation of mRNAs that encode the gag ...

Gene Products, tat - Trans-acting transcription factors produced by retroviruses such as HIV. They are nuclear proteins w...

Gene Products, tax - Transcriptional trans-acting proteins of the promoter elements found in the long terminal repeats (L...

Gene Products, vif - Retrovirally encoded accessary proteins that play an essential role VIRUS REPLICATION. They are foun...

Gene Products, vpr - Trans-acting proteins which accelerate retroviral virus replication. The vpr proteins act in trans t...

Glia Maturation Factor - A factor identified in the brain that influences the growth and differentiation of NEURONS and NEURO...

Gliadin - Simple protein, one of the prolamines, derived from the gluten of wheat, rye, etc. May be separated ...

Glial Cell Line-Derived Neurotrophic Factor - The founding member of the glial cell line-derived neurotrophic factor family. It was originally cha...

Glial Cell Line-Derived Neurotrophic Factor Receptors - A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored cell surface receptors that are specific for GLIAL...

Glial Cell Line-Derived Neurotrophic Factors - A family of closely related nerve growth factors that promote NEURON survival. They bind to GDNF REC...

Glial Fibrillary Acidic Protein - An intermediate filament protein found only in glial cells or cells of glial origin. MW 51,000....

Globins - A superfamily of proteins containing the globin fold which is composed of 6-8 alpha helices arrange...

Glucocorticoid-Induced TNFR-Related Protein - A member of the TNF receptor family that was initially identified as a DEXAMETHASONE-induced protein...

Glucose Transport Proteins, Facilitative - A family of monosaccharide transport proteins characterized by 12 membrane spanning helices. They fa...

Glucose Transporter Type 1 - A ubiquitously expressed glucose transporter that is important for constitutive, basal GLUCOSE trans...

Glucose Transporter Type 2 - A glucose transport facilitator that is expressed primarily in PANCREATIC BETA CELLS; LIVER; and KID...

Glucose Transporter Type 3 - A major glucose transporter found in NEURONS....

Glucose Transporter Type 4 - A glucose transport protein found in mature MUSCLE CELLS and ADIPOCYTES. It promotes transport of gl...

Glucose Transporter Type 5 - A hexose transporter that mediates FRUCTOSE transport in SKELETAL MUSCLE and ADIPOCYTES and is respo...

Glue Proteins, Drosophila - Glycosylated proteins which are part of the salivary glue that Drosophila larvae secrete as a means ...

Glutamate Plasma Membrane Transport Proteins - A family of plasma membrane neurotransmitter transporter proteins that couple the uptake of GLUTAMAT...

Glutamate Synthase (NADH) - A FLAVOPROTEIN enzyme for AMMONIA assimilation in BACTERIA, microorganisms and PLANTS. It catalyzes ...

Glutens - Prolamins in the endosperm of SEEDS from the Triticeae tribe which includes species of WHEAT; BARLEY...

Glycine Plasma Membrane Transport Proteins - A family of sodium chloride-dependent neurotransmitter symporters that transport the amino acid GLYC...

Glycogen Synthase Kinase 3 - A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabo...

Glycogen Synthase Kinases - A class of protein-serine-threonine kinases that was originally found as one of the three types of k...

Glycophorin - The major sialoglycoprotein of the human erythrocyte membrane. It consists of at least two sialoglyc...

Glycoprotein Hormones, alpha Subunit - The alpha chain of pituitary glycoprotein hormones (THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEI...

Glycoproteins - Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins....

Glypicans - A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored, cell-surface heparan sulfate proteoglycans that m...

Gonadotropin-Releasing Hormone - A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZI...

Gonadotropins, Equine - Gonadotropins secreted by the pituitary or the placenta in horses. This term generally refers to the...

Goosecoid Protein - Goosecoid protein is a homeodomain protein that was first identified in XENOPUS. It is found in the ...

Goserelin - A synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE. Goserelin is used in treatments o...

G-Protein-Coupled Receptor Kinase 1 - A PROTEIN-SERINE-THREONINE KINASE that is found in PHOTORECEPTOR CELLS. It mediates light-dependent ...

G-Protein-Coupled Receptor Kinase 2 - A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agon...

G-Protein-Coupled Receptor Kinase 3 - A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agon...

G-Protein-Coupled Receptor Kinase 4 - A G-protein-coupled receptor kinase subtype that is primarily expressed in the TESTES and BRAIN. Var...

G-Protein-Coupled Receptor Kinase 5 - A G-protein-coupled receptor kinase subtype that is primarily expressed in the MYOCARDIUM and may pl...

G-Protein-Coupled Receptor Kinases - A family of serine-threonine kinases that are specific for G-PROTEIN-COUPLED RECEPTORS. They are reg...

Gramicidin - A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid p...

Granulocyte Colony Stimulating Factor, Recombinant - Granulocyte colony stimulating factors prepared by recombinant DNA technology....

Granulocyte Colony-Stimulating Factor - A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferat...

Granulocyte Macrophage Colony-Stimulating Factors, Recombinant - Granulocyte-macrophage colony-stimulating factors prepared by recombinant DNA technology....

Granulocyte-Macrophage Colony-Stimulating Factor - An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in respon...

GRB10 Adaptor Protein - A binding partner for several RECEPTOR PROTEIN-TYROSINE KINASES, including INSULIN RECEPTOR and INSU...

GRB2 Adaptor Protein - A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SY...

GRB7 Adaptor Protein - A SH2 DOMAIN-containing protein that mediates SIGNAL TRANSDUCTION pathways from multiple CELL SURFAC...

Green Fluorescent Proteins - Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (...

Group I Chaperonins - A subcategory of chaperonins found in MITOCHONDRIA; CHLOROPLASTS; and BACTERIA. Group I chaperonins ...

Group II Chaperonins - A subcategory of chaperonins found in ARCHAEA and the CYTOSOL of eukaryotic cells. Group II chaperon...

Growth Differentiation Factor 1 - A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vert...

Growth Differentiation Factor 10 - A growth differentiation factor that is closely-related in structure to BONE MORPHOGENETIC PROTEIN 3...

Growth Differentiation Factor 15 - A growth differentiation factor that is secreted in response to cell stress and in response to MACRO...

Growth Differentiation Factor 2 - A growth differentiation factor that plays a regulatory role as a paracrine factor for a diverse arr...

Growth Differentiation Factor 3 - A growth differentiation factor that may play a role in maintaining the undifferentiated state of PL...

Growth Differentiation Factor 5 - A growth differentiation factor that plays a role in early CHONDROGENESIS and joint formation....

Growth Differentiation Factor 6 - A growth differentiation factor that plays a role in the neural differentiation, specifically in the...

Growth Differentiation Factor 9 - A bone morphogenetic protein that plays an essential role in the regulation of ovarian folliculogene...

Growth Differentiation Factors - A family of BONE MORPHOGENETIC PROTEIN-related proteins that are primarily involved in regulation of...

Growth Hormone-Releasing Hormone - A peptide of 44 amino acids in most species that stimulates the release and synthesis of GROWTH HORM...

GTP Phosphohydrolase-Linked Elongation Factors - Factors that utilize energy from the hydrolysis of GTP to GDP for peptide chain elongation. EC 3.6.1...

GTPase-Activating Proteins - Proteins that activate the GTPase of specific GTP-BINDING PROTEINS....

GTP-Binding Protein alpha Subunit, Gi2 - A PERTUSSIS TOXIN-sensitive GTP-binding protein alpha subunit. It couples with a variety of CELL SUR...

GTP-Binding Protein alpha Subunits - The GTPase-containing subunits of heterotrimeric GTP-binding proteins. When dissociated from the het...

GTP-Binding Protein alpha Subunits, G12-G13 - A ubiquitously expressed family of heterotrimeric GTP-binding protein alpha subunits that signal thr...

GTP-Binding Protein alpha Subunits, Gi-Go - A family of heterotrimeric GTP-binding protein alpha subunits that were originally identified by the...

GTP-Binding Protein alpha Subunits, Gq-G11 - A family of heterotrimeric GTP-binding protein alpha subunits that activate TYPE C PHOSPHOLIPASES de...

GTP-Binding Protein alpha Subunits, Gs - A family of heterotrimeric GTP-binding protein alpha subunits that activate ADENYLATE CYCLASE....

GTP-Binding Protein beta Subunits - Heterotrimeric GTP-binding protein subunits that tightly associate with GTP-BINDING PROTEIN GAMMA SU...

GTP-Binding Protein gamma Subunits - Heterotrimeric GTP-binding protein subunits that tightly associate with GTP-BINDING PROTEIN BETA SUB...

GTP-Binding Protein Regulators - Proteins that regulate the signaling activity of GTP-BINDING PROTEINS. They are divided into three c...

GTP-Binding Proteins - Regulatory proteins that act as molecular switches. They control a wide range of biological processe...

Guanine Nucleotide Dissociation Inhibitors - Protein factors that inhibit the dissociation of GDP from GTP-BINDING PROTEINS....

Guanine Nucleotide Exchange Factors - Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS....

Guanine Nucleotide-Releasing Factor 2 - A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS....

Guanylate Cyclase - An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts o...

Guanylate Cyclase-Activating Proteins - Neuronal calcium sensor proteins that regulate the activation of membrane-bound GUANYLATE CYCLASE. T...

H(+)-K(+)-Exchanging ATPase - An enzyme isolated from the gastric mucosa that catalyzes the hydrolysis of ATP coupled with the exc...

Halorhodopsins - Light driven chloride ion pumps that are ubiquitously found in halophilic archaea (HALOBACTERIALES)....

Haptoglobins - Plasma glycoproteins that form a stable complex with hemoglobin to aid the recycling of heme iron. T...

Heat-Shock Proteins - Proteins which are synthesized in eukaryotic organisms and bacteria in response to hyperthermia and ...

Heat-Shock Proteins, Small - A family of low molecular weight heat-shock proteins that can serve as MOLECULAR CHAPERONES....

Hedgehog Proteins - A family of intercellular signaling proteins that play and important role in regulating the developm...

Helminth Proteins - Proteins found in any species of helminth....

Hemagglutinin Glycoproteins, Influenza Virus - Membrane glycoproteins from influenza viruses which are involved in hemagglutination, virus attachme...

Hemagglutinins, Viral - Specific hemagglutinin subtypes encoded by VIRUSES....

Hematopoietic Cell Growth Factors - These growth factors comprise a family of hematopoietic regulators with biological specificities def...

Hemeproteins - Proteins that contain an iron-porphyrin, or heme, prosthetic group resembling that of hemoglobin. (F...

Hemerythrin - A non-heme iron protein consisting of eight apparently identical subunits each containing 2 iron ato...

Hemoglobin A - Normal adult human hemoglobin. The globin moiety consists of two alpha and two beta chains....

Hemoglobin A, Glycosylated - Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is mo...

Hemoglobin A2 - An adult hemoglobin component normally present in hemolysates from human erythrocytes in concentrati...

Hemoglobin C - A commonly occurring abnormal hemoglobin in which lysine replaces a glutamic acid residue at the six...

Hemoglobin E - An abnormal hemoglobin that results from the substitution of lysine for glutamic acid at position 26...

Hemoglobin H - An abnormal hemoglobin composed of four beta chains. It is caused by the reduced synthesis of the al...

Hemoglobin J - A group of abnormal hemoglobins with similar electrophoretic characteristics. They have faster elect...

Hemoglobin M - A group of abnormal hemoglobins in which amino acid substitutions take place in either the alpha or ...

Hemoglobin Subunits - The PROTEIN SUBUNITS that comprise multimeric HEMOGLOBINS....

Hemoglobin, Sickle - An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of ...

Hemoglobins - The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrat...

Hemoglobins, Abnormal - Hemoglobins characterized by structural alterations within the molecule. The alteration can be eithe...

Hemolysin Proteins - Proteins from BACTERIA and FUNGI that are soluble enough to be secreted to target ERYTHROCYTES and i...

Heparan Sulfate Proteoglycans - Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range ...

Heparin Cofactor II - A sulfated plasma protein with the MW of approximately 66kDa that resembles ANTITHROMBIN III. The pr...

Hepatitis A Antibodies - Antibodies to the HEPATITIS A ANTIGENS including antibodies to envelope, core, and non-structural pr...

Hepatitis Antibodies - Immunoglobulins raised by any form of viral hepatitis; some of these antibodies are used to diagnose...

Hepatitis B Antibodies - Antibodies to the HEPATITIS B ANTIGENS, including antibodies to the surface (Australia) and core of ...

Hepatitis C Antibodies - Antibodies to the HEPATITIS C ANTIGENS including antibodies to envelope, core, and non-structural pr...

Hepatocyte Growth Factor - Multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong...

Hepatocyte Nuclear Factor 1 - A transcription factor that regulates the expression of a large set of hepatic proteins including SE...

Hepatocyte Nuclear Factor 1-alpha - Hepatocyte nuclear factor 1-alpha is a transcription factor found in the LIVER; PANCREAS; and KIDNEY...

Hepatocyte Nuclear Factor 1-beta - A hepatocyte nuclear factor that is closely related to HEPATOCYTE NUCLEAR FACTOR 1-ALPHA but is only...

Hepatocyte Nuclear Factor 3-alpha - A forkhead transcription factor that is an essential activator of GLUCAGON gene expression....

Hepatocyte Nuclear Factor 3-beta - A forkhead transcription factor that regulates expression of metabolic GENES and is involved in EMBR...

Hepatocyte Nuclear Factor 3-gamma - A winged-helix transcription factor that regulates GENE expression in metabolic tissues. It plays a ...

Hepatocyte Nuclear Factor 4 - A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES inv...

Hepatocyte Nuclear Factor 6 - A onecut transcription factor that regulates expression of GENES involved in EMBRYONIC DEVELOPMENT o...

Hepatocyte Nuclear Factors - Hepatocyte nuclear factors are a family of evolutionarily conserved transcription factors that are p...

Herpes Simplex Virus Protein Vmw65 - Trans-acting protein that combines with host factors to induce immediate early gene transcription in...

Heterochromatin - The portion of chromosome material that remains condensed and is transcriptionally inactive during I...

Heterogeneous-Nuclear Ribonucleoprotein D - A heterogeneous-nuclear ribonucleoprotein that has specificity for AU-rich elements found in the 3'-...

Heterogeneous-Nuclear Ribonucleoprotein Group A-B - A class of closely related heterogeneous-nuclear ribonucleoproteins of approximately 34-40 kDa in si...

Heterogeneous-Nuclear Ribonucleoprotein Group C - A group of closely related heterogeneous-nuclear ribonucleoproteins of approximately 41-43 kDa in si...

Heterogeneous-Nuclear Ribonucleoprotein Group F-H - A group of closely-related heterogeneous-nuclear ribonucleoproteins that are involved in pre-mRNA sp...

Heterogeneous-Nuclear Ribonucleoprotein Group M - A group of closely-related 72-74-kDa heterogeneous-nuclear ribonucleoproteins that are involved in R...

Heterogeneous-Nuclear Ribonucleoprotein K - A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous...

Heterogeneous-Nuclear Ribonucleoprotein L - A heterogenous-nuclear ribonucleoprotein found associated with most nascent transcripts, most notabl...

Heterogeneous-Nuclear Ribonucleoprotein U - A heterogeneous-nuclear ribonucleoprotein found associated with the NUCLEAR MATRIX....

Heterogeneous-Nuclear Ribonucleoproteins - A family of ribonucleoproteins that were originally found as proteins bound to nascent RNA transcrip...

Heterotrimeric GTP-Binding Proteins - GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with membe...

High Mobility Group Proteins - A family of low-molecular weight, non-histone proteins found in chromatin....

High-Density Lipoproteins, Pre-beta - A highly dense subclass of the high-density lipoproteins, with particle sizes below 7 nm. They are a...

Hippocalcin - A neuronal calcium-sensor protein that was initially found in the NEURONS of the HIPPOCAMPUS. It int...

Hirudins - Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophob...

Histatins - A group of small, histidine-rich, cationic peptides in human SALIVA which are antibacterial and anti...

Histone Chaperones - Proteins involved in the assembly and disassembly of HISTONES into NUCLEOSOMES....

Histones - Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to ...

HIV Antibodies - Antibodies reactive with HIV ANTIGENS....

HIV Core Protein p24 - A major core protein of the human immunodeficiency virus encoded by the HIV gag gene. HIV-seropositi...

HIV Envelope Protein gp120 - External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. ...

HIV Envelope Protein gp160 - An envelope protein of the human immunodeficiency virus that is encoded by the HIV env gene. It has ...

HIV Envelope Protein gp41 - Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env g...

HIV Integrase - Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA...

HIV Protease - Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag a...

HIV Reverse Transcriptase - A reverse transcriptase encoded by the POL GENE of HIV. It is a heterodimer of 66 kDa and 51 kDa sub...

HMGA Proteins - Proteins containing AT-HOOK MOTIFS that are rich in arginine and glycine residues. They bind to the ...

HMGA1a Protein - An 11-kDa AT-hook motif-containing (AT-HOOK MOTIFS) protein that binds to the minor grove of AT-rich...

HMGA1b Protein - An AT-hook motif-containing protein (AT-HOOK MOTIFS) that binds to the minor grove of AT-rich region...

HMGA1c Protein - An AT-hook-containing (AT-HOOK MOTIFS) nuclear protein that may be involved in retinoid-dependent tr...

HMGA2 Protein - An AT-hook-containing (AT-HOOK MOTIFS) nuclear protein that is expressed predominantly in proliferat...

HMGB Proteins - A family of sequence-related proteins similar to HMGB1 PROTEIN that contains specific HMG-BOX DOMAIN...

HMGB1 Protein - A 24-kDa HMGB protein that binds to and distorts the minor grove of DNA....

HMGB2 Protein - A 23-kDa HMG-box protein that binds to and distorts the minor grove of DNA....

HMGB3 Protein - An HMG-box domain (HMG-BOX DOMAINS) found highly expressed in embryonic tissue and in placenta....

HMGN Proteins - A family of HIGH MOBILITY GROUP PROTEINS that bind to NUCLEOSOMES....

HMGN1 Protein - An evolutionarily-conserved 10-kDa nuclear protein that binds NUCLEOSOMES and may be involved in the...

HMGN2 Protein - An evolutionarily conserved 9-KDa nuclear protein that binds NUCLEOSOMES and may be involved in the ...

HN Protein - Glycoprotein from Sendai, para-influenza, Newcastle Disease, and other viruses that participates in ...

Homeodomain Proteins - Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain p...

Host Cell Factor C1 - A cellular transcriptional coactivator that was originally identified by its requirement for the sta...

Host Factor 1 Protein - An integration host factor that was originally identified as a bacterial protein required for the in...

HSC70 Heat-Shock Proteins - A constitutively expressed subfamily of the HSP70 heat-shock proteins. They preferentially bind and ...

HSP110 Heat-Shock Proteins - A group of eukaryotic high-molecular mass heat-shock proteins that represent a subfamily of HSP70 HE...

HSP20 Heat-Shock Proteins - A subfamily of small heat-shock proteins that are closely related to ALPHA B-CRYSTALLIN. Hsp20 heat-...

HSP27 Heat-Shock Proteins - A subfamily of small heat-shock proteins that function as molecular chaperones that aid in refolding...

HSP30 Heat-Shock Proteins - A subfamily of small heat-shock proteins found in a wide variety of organisms....

HSP40 Heat-Shock Proteins - A family of heat-shock proteins that contain a 70 amino-acid consensus sequence known as the J domai...

HSP47 Heat-Shock Proteins - Basic glycoprotein members of the SERPIN SUPERFAMILY that function as COLLAGEN-specific MOLECULAR CH...

HSP70 Heat-Shock Proteins - A class of MOLECULAR CHAPERONES found in both prokaryotes and in several compartments of eukaryotic ...

HSP72 Heat-Shock Proteins - Stress-inducible members of the heat-shock proteins 70 family. HSP72 heat shock proteins function w...

HSP90 Heat-Shock Proteins - A class of MOLECULAR CHAPERONES whose members act in the mechanism of SIGNAL TRANSDUCTION by STEROID...

HTLV-I Antibodies - Antibodies reactive with the HTLV-I ANTIGENS....

HTLV-II Antibodies - Antibodies reactive with the HTLV-II ANTIGENS....

Hu Paraneoplastic Encephalomyelitis Antigens - A family of RNA-binding proteins that are homologues of ELAV protein, Drosophila. They were initiall...

Human Immunodeficiency Virus Proteins - Proteins synthesized by HUMAN IMMUNODEFICIENCY VIRUSES such as the HIV-1 and HIV-2....

Hypothalamic Hormones - Peptide hormones produced by NEURONS of various regions in the HYPOTHALAMUS. They are released into ...

Hypoxia-Inducible Factor 1 - A basic helix-loop-helix transcription factor that plays a role in APOPTOSIS. It is composed of two ...

Hypoxia-Inducible Factor 1, alpha Subunit - Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is r...

I-kappa B Kinase - A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enz...

I-kappa B Proteins - A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their act...

Ikaros Transcription Factor - A transcription factor that plays a role as a key regulator of HEMATOPOIESIS. Aberrant Ikaros expres...

Imidazoline Receptors - Receptors of CLONIDINE and other IMIDAZOLINES. Activity of the ligands was earlier attributed to ADR...

Immediate-Early Proteins - Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The t...

Immobilized Proteins - Proteins that are chemically bound to a substrate material which renders their location fixed. The i...

Immune Sera - Serum that contains antibodies. It is obtained from an animal that has been immunized either by ANTI...

Immunoconglutinins - Autoantibodies directed against newly-formed EPITOPES created as the COMPLEMENT cascade is activated...

Immunoconjugates - Combinations of diagnostic or therapeutic substances linked with specific immune substances such as ...

Immunoglobulin A - Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dim...

Immunoglobulin A, Secretory - The principle immunoglobulin in exocrine secretions such as milk, respiratory and intestinal mucin, ...

Immunoglobulin Allotypes - Allelic variants of the immunoglobulin light chains (IMMUNOGLOBULIN LIGHT CHAINS) or heavy chains (I...

Immunoglobulin alpha-Chains - The class of heavy chains found in IMMUNOGLOBULIN A. They have a molecular weight of approximately 5...

Immunoglobulin Constant Regions - The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within ...

Immunoglobulin D - An immunoglobulin which accounts for less than 1% of plasma immunoglobulin. It is found on the membr...

Immunoglobulin delta-Chains - The class of heavy chains found in IMMUNOGLOBULIN D. They have a molecular weight of approximately 6...

Immunoglobulin E - An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hyper...

Immunoglobulin epsilon-Chains - The class of heavy chains found in IMMUNOGLOBULIN E. They have a molecular weight of approximately 7...

Immunoglobulin Fab Fragments - Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino ...

Immunoglobulin Fc Fragments - Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS...

Immunoglobulin Fragments - Partial immunoglobulin molecules resulting from selective cleavage by proteolytic enzymes or generat...

Immunoglobulin G - The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses o...

Immunoglobulin gamma-Chains - Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain abo...

Immunoglobulin Gm Allotypes - Allelic variants of the gamma-immunoglobulin heavy chain (IMMUNOGLOBULIN GAMMA-CHAINS) encoded by AL...

Immunoglobulin Heavy Chains - The largest of polypeptide chains comprising immunoglobulins. They contain 450 to 600 amino acid res...

Immunoglobulin Idiotypes - Unique, genetically controlled determinants present on ANTIBODIES whose specificity is limited to a ...

Immunoglobulin Isotypes - The classes of immunoglobulins found in any species of animal. In man there are nine classes that mi...

Immunoglobulin J Recombination Signal Sequence-Binding Protein - A ubiquitously expressed sequence-specific transcriptional repressor that is normally the target of ...

Immunoglobulin J-Chains - A 15 kD "joining" peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMM...

Immunoglobulin Joining Region - A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the...

Immunoglobulin kappa-Chains - One of the types of light chains of the immunoglobulins with a molecular weight of approximately 22 ...

Immunoglobulin Km Allotypes - Allelic variants of the kappa light chains (IMMUNOGLOBULIN KAPPA-CHAINS) encoded by ALLELES of IMMUN...

Immunoglobulin lambda-Chains - One of the types of light chain subunits of the immunoglobulins with a molecular weight of approxima...

Immunoglobulin Light Chains - Polypeptide chains, consisting of 211 to 217 amino acid residues and having a molecular weight of ap...

Immunoglobulin Light Chains, Surrogate - An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like pepti...

Immunoglobulin M - A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The ...

Immunoglobulin mu-Chains - The class of heavy chains found in IMMUNOGLOBULIN M. They have a molecular weight of approximately 7...

Immunoglobulin Subunits - The PROTEIN SUBUNITS of the multimeric IMMUNOGLOBULIN proteins, such as IGA; IGD; IGE; IGG; and IGM....

Immunoglobulin Variable Region - That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, a...

Immunoglobulins - Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUN...

Immunoglobulins, Intravenous - Immunoglobulin preparations used in intravenous infusion, containing primarily IMMUNOGLOBULIN G. The...

Immunoglobulins, Thyroid-Stimulating - Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) ...

Immunophilins - Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases ...

Immunoproteins - Blood proteins whose activities affect or play a role in the functioning of the immune system....

Immunotoxins - Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or...

Inhibin-beta Subunits - They are glycopeptides and subunits in INHIBINS and ACTIVINS. Inhibins and activins belong to the tr...

Inhibins - Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted b...

Inhibitor of Apoptosis Proteins - A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP prot...

Inhibitor of Differentiation Protein 1 - A negative regulator of BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS that blocks activation of CYCLI...

Inhibitor of Differentiation Protein 2 - A negative regulator of BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS. It plays a role in regulating ...

Inhibitor of Differentiation Proteins - Inhibitor of differentiation proteins are negative regulators of BASIC HELIX-LOOP-HELIX TRANSCRIPTIO...

Inorganic Pyrophosphatase - An enzyme which catalyzes the hydrolysis of diphosphate (DIPHOSPHATES) into inorganic phosphate. The...

Inositol 1,4,5-Trisphosphate Receptors - Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its ...

Inositol Oxygenase - A non-heme IRON enzyme that catalyzes the conversion of MYOINOSITOL to D-glucuronic acid. The reacti...

Insect Proteins - Proteins found in any species of insect....

Insulin Antibodies - Antibodies specific to INSULIN....

Insulin Receptor Substrate Proteins - A structurally-related group of signaling proteins that are phosphorylated by the INSULIN RECEPTOR P...

Insulin-Like Growth Factor Binding Protein 1 - One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS)...

Insulin-Like Growth Factor Binding Protein 2 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and ...

Insulin-Like Growth Factor Binding Protein 3 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and ...

Insulin-Like Growth Factor Binding Protein 4 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and ...

Insulin-Like Growth Factor Binding Protein 5 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and ...

Insulin-Like Growth Factor Binding Protein 6 - One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and ...

Insulin-Like Growth Factor Binding Proteins - A family of soluble proteins that bind insulin-like growth factors and modulate their biological act...

Insulin-Like Growth Factor I - A well-characterized basic peptide believed to be secreted by the liver and to circulate in the bloo...

Insulin-Like Growth Factor II - A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BL...

Integration Host Factors - Bacterial proteins that are used by BACTERIOPHAGES to incorporate their DNA into the DNA of the "hos...

Integrin alpha Chains - The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are...

Integrin alpha1 - An integrin alpha subunit that binds COLLAGEN and LAMININ though its I domain. It combines with INTE...

Integrin alpha1beta1 - Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed durin...

Integrin alpha2 - An integrin alpha subunit that primarily combines with INTEGRIN BETA1 to form the INTEGRIN ALPHA2BET...

Integrin alpha2beta1 - An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where...

Integrin alpha3 - An integrin alpha subunit that occurs as alternatively spliced isoforms. The isoforms are differenti...

Integrin alpha3beta1 - Cell surface receptor for LAMININ, epiligrin, FIBRONECTINS, entactin, and COLLAGEN. Integrin alpha3...

Integrin alpha4 - An integrin alpha subunit that is unique in that it does not contain an I domain, and its proteolyti...

Integrin alpha4beta1 - Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOP...

Integrin alpha5 - This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) t...

Integrin alpha5beta1 - An integrin found in FIBROBLASTS; PLATELETS; MONOCYTES, and LYMPHOCYTES. Integrin alpha5beta1 is the...

Integrin alpha6 - An integrin alpha subunit that primarily associates with INTEGRIN BETA1 or INTEGRIN BETA4 to form la...

Integrin alpha6beta1 - A cell surface receptor mediating cell adhesion to the EXTRACELLULAR MATRIX and to other cells via b...

Integrin alpha6beta4 - This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenan...

Integrin alphaV - An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It u...

Integrin alphaVbeta3 - An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conse...

Integrin alphaXbeta2 - A major adhesion-associated heterodimer molecule expressed by MONOCYTES; GRANULOCYTES; NK CELLS; and...

Integrin beta Chains - Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors...

Integrin beta3 - An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-c...

Integrin beta4 - Also known as CD104 antigen, this protein is distinguished from other beta integrins by its relative...

Integrins - A family of transmembrane glycoproteins (MEMBRANE GLYCOPROTEINS) consisting of noncovalent heterodim...

Intercellular Adhesion Molecule-1 - A cell-surface ligand involved in leukocyte adhesion and inflammation. Its production is induced by ...

Intercellular Signaling Peptides and Proteins - Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE C...

Interferon Alfa-2a - A recombinant alfa interferon consisting of 165 amino acids with lysine at position 23 and histidine...

Interferon Alfa-2b - A recombinant alfa interferon consisting of 165 amino acid residues with arginine in position 23 and...

Interferon Alfa-2c - A recombinant alfa interferon consisting of 165 amino acids with arginine at positions 23 and 34. It...

Interferon Regulatory Factor-1 - An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES...

Interferon Regulatory Factor-2 - An interferon regulatory factor that represses transcription of TYPE I INTERFERONS and activates tra...

Interferon Regulatory Factor-3 - An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MO...

Interferon Regulatory Factor-7 - An interferon regulatory factor that is induced by INTERFERONS as well as LMP-1 protein from EPSTEIN...

Interferon Regulatory Factors - A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERO...

Interferon Type I - Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon...

Interferon Type I, Recombinant - A type I interferon with antiviral and antineoplastic activity produced by recombinant DNA technolog...

Interferon-alpha - One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In ad...

Interferon-beta - One of the type I interferons produced by fibroblasts in response to stimulation by live or inactiva...

Interferon-gamma - The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is struct...

Interferon-gamma, Recombinant - A type II interferon produced by recombinant DNA technology. It is similar to the interferon secrete...

Interferons - Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resista...

Interferon-Stimulated Gene Factor 3 - A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled i...

Interferon-Stimulated Gene Factor 3, alpha Subunit - A heterodimeric complex of STAT1 PROTEIN and STAT2 PROTEIN that interacts with ISGF3GAMMA and is a s...

Interferon-Stimulated Gene Factor 3, gamma Subunit - An interferon regulatory factor that recruits STAT1 PROTEIN and STAT2 PROTEIN heterodimers to interf...

Interleukin 1 Receptor Antagonist Protein - A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role...

Interleukin Receptor Common gamma Subunit - An interleukin receptor subunit that was originally discovered as a component of the INTERLEUKIN 2 R...

Interleukin-1 - A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes a...

Interleukin-1 Receptor Accessory Protein - A protein that takes part in the formation of active interleukin-1 receptor complex. It binds specif...

Interleukin-1 Receptor-Associated Kinases - A family of intracellular signaling kinases that were identified by their ability to signal from the...

Interleukin-10 - A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS;...

Interleukin-10 Receptor alpha Subunit - A subunit of the interleukin-10 receptor. It plays a role in receptor signaling by associating with ...

Interleukin-10 Receptor beta Subunit - A subunit of the interleukin-10 receptor. It plays a role in receptor signaling by associating with ...

Interleukin-11 - A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PRECUR...

Interleukin-11 Receptor alpha Subunit - A low affinity interleukin-11 receptor subunit that combines with the CYTOKINE RECEPTOR GP130 to for...

Interleukin-12 - A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 i...

Interleukin-12 Receptor beta 1 Subunit - A subunit of the interleukin-12 receptor. It plays a role in receptor signaling by associating with ...

Interleukin-12 Receptor beta 2 Subunit - A subunit of the interleukin-12 receptor. It plays a role in receptor signaling by associating with ...

Interleukin-12 Subunit p35 - A subunit of interleukin-12. It binds to the INTERLEUKIN-12 SUBUNIT P40 via a disulfide bond that re...

Interleukin-12 Subunit p40 - A cytokine subunit that is a component of both interleukin-12 and interleukin-23. It binds to the IN...

Interleukin-13 - A cytokine synthesized by T-LYMPHOCYTES that produces proliferation, immunoglobulin isotype switchin...

Interleukin-13 Receptor alpha1 Subunit - An interleukin receptor subunit with specificity for INTERLEUKIN-13. It dimerizes with the INTERLEUK...

Interleukin-13 Receptor alpha2 Subunit - An interleukin-13 receptor subunit that is closely-related to the INTERLEUKIN-13 RECEPTOR ALPHA1 SUB...

Interleukin-15 - Cytokine that stimulates the proliferation of T-LYMPHOCYTES and shares biological activities with IL...

Interleukin-15 Receptor alpha Subunit - A low affinity interleukin-15 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SU...

Interleukin-16 - A cytokine produced by activated T-LYMPHOCYTES that stimulates the migration of CD4-POSITIVE LYMPHOC...

Interleukin-17 - A proinflammatory cytokine produced primarily by T-LYMPHOCYTES or their precursors. Several subtypes...

Interleukin-18 - A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activ...

Interleukin-18 Receptor alpha Subunit - A subunit of the interleukin-18 receptor that is responsible of extracellular binding of IL-18....

Interleukin-18 Receptor beta Subunit - A subunit of the interleukin-18 receptor that plays a role in receptor signaling by association of i...

Interleukin-1alpha - An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteas...

Interleukin-1beta - An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic ...

Interleukin-2 - A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA syn...

Interleukin-2 Receptor alpha Subunit - A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUB...

Interleukin-2 Receptor beta Subunit - A receptor subunit that is a shared component of the INTERLEUKIN 2 RECEPTOR and the INTERLEUKIN-15 R...

Interleukin-21 Receptor alpha Subunit - An interleukin-21 receptor subunit that combines with the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT ...

Interleukin-23 - A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 i...

Interleukin-23 Subunit p19 - A subunit of interleukin-23. It combines with INTERLEUKIN-12 SUBUNIT P40, which is shared between th...

Interleukin-3 - A multilineage cell growth factor secreted by LYMPHOCYTES; EPITHELIAL CELLS; and ASTROCYTES which st...

Interleukin-3 Receptor alpha Subunit - A low affinity interleukin-3 receptor subunit that combines with the CYTOKINE RECEPTOR COMMON BETA S...

Interleukin-4 - A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GEN...

Interleukin-4 Receptor alpha Subunit - A receptor subunit that is a component of the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEU...

Interleukin-5 - A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B...

Interleukin-5 Receptor alpha Subunit - A low affinity interleukin-5 receptor subunit that combines with the CYTOKINE RECEPTOR COMMON BETA S...

Interleukin-6 - A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth fact...

Interleukin-6 Receptor alpha Subunit - A low affinity interleukin-6 receptor subunit that combines with the CYTOKINE RECEPTOR GP130 to form...

Interleukin-7 - A cytokine produced by bone marrow stromal cells that promotes the growth of B-LYMPHOCYTE precursors...

Interleukin-7 Receptor alpha Subunit - A low affinity interleukin-7 receptor subunit that combines with the INTERLEUKIN RECEPTOR COMMON GAM...

Interleukin-8 - A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory r...

Interleukin-9 - A multifunctional cytokine secreted by primarily by activated TH2 CELLS that may play a role as a re...

Interleukins - Soluble factors which stimulate growth-related activities of leukocytes as well as other cell types....

Intermediate Filament Proteins - Filaments 7-11 nm in diameter found in the cytoplasm of all cells. Many specific proteins belong to ...

Intermediate-Conductance Calcium-Activated Potassium Channels - A major class of calcium-activated potassium channels that were originally discovered in ERYTHROCYTE...

Intracellular Calcium-Sensing Proteins - Intracellular signaling peptides and proteins that bind to CALCIUM. They undergo allosteric changes ...

Intracellular Signaling Peptides and Proteins - Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are pe...

Intrinsic Factor - A glycoprotein secreted by the cells of the GASTRIC GLANDS that is required for the absorption of VI...

Ion Channels - Gated, ion-selective glycoproteins that traverse membranes. The stimulus for channel gating can be a...

Ion Pumps - A general class of integral membrane proteins that transport ions across a membrane against an elect...

Iron Regulatory Protein 1 - A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form o...

Iron Regulatory Protein 2 - A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form o...

Iron-Binding Proteins - Proteins that specifically bind to IRON....

Iron-Regulatory Proteins - Proteins that regulate cellular and organismal iron homeostasis. They play an important biological r...

Iron-Sulfur Proteins - A group of proteins possessing only the iron-sulfur complex as the prosthetic group. These proteins ...

Isoantibodies - Antibodies from an individual that react with ISOANTIGENS of another individual of the same species....

Isoenzymes - Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, b...

Janus Kinase 1 - A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS....

Janus Kinase 2 - A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPT...

Janus Kinase 3 - A Janus kinase subtype that is predominantly expressed in hematopoietic cell. It is involved in sign...

Janus Kinases - A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by...

JNK Mitogen-Activated Protein Kinases - A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phos...

Kallidin - A decapeptide bradykinin homolog cleaved from kininogen by kallikreins. It is a smooth-muscle stimul...

Kallikreins - Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifical...

Kangai-1 Protein - A widely expressed transmembrane glycoprotein that functions as a METASTASIS suppressor protein. It ...

Karyopherins - A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules...

Kassinin - Dodecapeptide tachykinin found in the central nervous system of the amphibian Kassina senegalensis. ...

KATP Channels - Heteromultimers of Kir6 channels (the pore portion) and sulfonylurea receptor (the regulatory portio...

KCNQ Potassium Channels - A family of delayed rectifier voltage-gated potassium channels that share homology with their foundi...

KCNQ1 Potassium Channel - A voltage-gated potassium channel that is expressed primarily in the HEART....

KCNQ2 Potassium Channel - A very slow opening and closing voltage-gated potassium channel that is expressed in NEURONS and is ...

KCNQ3 Potassium Channel - A very slow opening and closing voltage-gated potassium channel that is expressed in NEURONS and is ...

Keratin-1 - A type II keratin that is found associated with the KERATIN-10 in terminally differentiated epiderma...

Keratin-10 - A type I keratin that is found associated with the KERATIN-1 in terminally differentiated epidermal ...

Keratin-12 - A type I keratin that is found associated with the KERATIN-3 in the CORNEA and is regarded as a mark...

Keratin-13 - A type I keratin that is found associated with the KERATIN-4 in the internal stratified EPITHELIUM. ...

Keratin-14 - A type I keratin that is found associated with the KERATIN-5 in the internal stratified EPITHELIUM. ...

Keratin-15 - A type I keratin found in the basal layer of the adult epidermis and in other stratified epithelia....

Keratin-16 - A type I keratin expressed in a variety of EPITHELIUM, including the ESOPHAGUS, the TONGUE, the HAIR...

Keratin-17 - A type I keratin found associated with KERATIN-6 in rapidly proliferating squamous epithelial tissue...

Keratin-18 - A type I keratin found associated with KERATIN-8 in simple, or predominately single layered, interna...

Keratin-19 - A type I keratin found associated with KERATIN-7 in ductal epithelia and gastrointestinal epithelia....

Keratin-2 - A type II keratin found expressed in the upper spinous layer of epidermal KERATINOCYTES. Mutations i...

Keratin-20 - A type I keratin expressed predominately in gastrointestinal epithelia, MERKEL CELLS, and the TASTE ...

Keratin-3 - A type II keratin that is found associated with the KERATIN-12 in the CORNEA and is regarded as a ma...

Keratin-4 - A type II keratin that is found associated with the KERATIN-13 in the internal stratified EPITHELIUM...

Keratin-5 - A type II keratin that is found associated with the KERATIN-14 in the internal stratified EPITHELIUM...

Keratin-6 - A type II keratin found associated with KERATIN-16 or KERATIN-17 in rapidly proliferating squamous e...

Keratin-7 - A type II keratin found associated with KERATIN-19 in ductal epithelia and gastrointestinal epitheli...

Keratin-8 - A type II keratin found associated with KERATIN-18 in simple, or predominately single layered, inter...

Keratin-9 - A type II keratin found predominantly expressed in the terminally differentiated EPIDERMIS of palms ...

Keratins - A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS...

Keratins, Hair-Specific - Keratins that are specific for hard tissues such as HAIR; NAILS; and the filiform papillae of the TO...

Keratins, Type I - A keratin subtype that includes keratins that are generally smaller and more acidic that TYPE II KER...

Keratins, Type II - A keratin subtype that includes keratins that are generally larger and less acidic that TYPE I KERAT...

Ki-67 Antigen - A CELL CYCLE and tumor growth marker which can be readily detected using IMMUNOCYTOCHEMISTRY methods...

Killer Factors, Yeast - Protein factors released from one species of YEAST that are selectively toxic to another species of ...

Kinesin - A microtubule-associated mechanical adenosine triphosphatase, that uses the energy of ATP hydrolysis...

Kininogen, High-Molecular-Weight - A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with P...

Kininogen, Low-Molecular-Weight - A protein, molecular weight 50 kD, located in various normal tissues. Upon cleavage by KALLIKREINS, ...

Kininogens - Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which...

Kinins - A generic term used to describe a group of polypeptides with related chemical structures and pharmac...

Kruppel-Like Transcription Factors - A family of zinc finger transcription factors that share homology with Kruppel protein, Drosophila. ...

Kv Channel-Interacting Proteins - A family of neuronal calcium-sensor proteins that interact with and regulate potassium channels, typ...

Kv1.1 Potassium Channel - A delayed rectifier subtype of shaker potassium channels that is commonly mutated in human episodic ...

Kv1.2 Potassium Channel - A delayed rectifier subtype of shaker potassium channels that is selectively inhibited by a variety ...

Kv1.3 Potassium Channel - A delayed rectifier subtype of shaker potassium channels that is the predominant VOLTAGE-GATED POTAS...

Kv1.4 Potassium Channel - A fast inactivating subtype of shaker potassium channels that contains two inactivation domains at i...

Kv1.5 Potassium Channel - A delayed rectifier subtype of shaker potassium channels that conducts a delayed rectifier current. ...

Kv1.6 Potassium Channel - A delayed rectifier subtype of shaker potassium channels that has been described in NEURONS and ASTR...

Lac Repressors - Bacterial repressor proteins that bind to the LAC OPERON and thereby prevent the synthesis of protei...

Lactoferrin - An iron-binding protein in plasma and secretions (milk, mucus, bile), secreted by leukocytes. It is ...

Lactoglobulins - Globulins occurring in milk. (From Dorland, 28th ed)...

Lamin Type A - A subclass of developmentally regulated lamins having a neutral isoelectric point. They are found to...

Lamin Type B - A subclass of ubiquitously-expressed lamins having an acidic isoelectric point. They are found to re...

Laminin - Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membra...

Lamins - Nuclear matrix proteins that are structural components of the NUCLEAR LAMINA. They are found in most...

Large Neutral Amino Acid-Transporter 1 - A CD98 antigen light chain that when heterodimerized with CD98 antigen heavy chain (ANTIGENS, CD98 H...

Large-Conductance Calcium-Activated Potassium Channel alpha Subunits - The pore-forming subunits of large-conductance calcium-activated potassium channels. They form tetra...

Large-Conductance Calcium-Activated Potassium Channel beta Subunits - The regulatory subunits of large-conductance calcium-activated potassium channels....

Large-Conductance Calcium-Activated Potassium Channels - A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK cha...

Latent TGF-beta Binding Proteins - A family of secreted multidomain proteins that were originally identified by their association with ...

LDL-Receptor Related Protein 1 - A LDL-receptor related protein involved in clearance of chylomicron remnants and of activated ALPHA-...

LDL-Receptor Related Protein 2 - An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the ki...

LDL-Receptor Related Protein-Associated Protein - A membrane protein found in the rough endoplasm reticulum (ENDOPLASMIC RETICULUM, ROUGH) that binds ...

LDL-Receptor Related Proteins - A family of proteins that share sequence similarity with the low density lipoprotein receptor (RECEP...

Lectins - Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbo...

Lectins, C-Type - A class of animal lectins that bind to carbohydrate in a calcium-dependent manner. They share a comm...

Left-Right Determination Factors - Signaling ligands that act in opposition to NODAL PROTEIN. During vertebrate development they regula...

Leghemoglobin - A hemoglobin-like oxygen-binding hemeprotein present in the nitrogen-fixing root nodules of legumino...

Leptin - A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat...

Leucine-Responsive Regulatory Protein - A LEUCINE and DNA-binding protein that is found primarily in BACTERIA and ARCHAEA. It regulates GENE...

Leukemia Inhibitory Factor - An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems t...

Leukemia Inhibitory Factor Receptor alpha Subunit - A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor ...

Leukocidins - Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS pro...

Leukocyte L1 Antigen Complex - A member of the S-100 protein family that is present at high levels in the blood and interstitial fl...

Leukocyte Migration-Inhibitory Factors - Protein factor(s) released by sensitized lymphocytes (and possibly other cells) that inhibit the mov...

Leuprolide - A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that regulates the synthesi...

Light-Harvesting Protein Complexes - Complexes containing CHLOROPHYLL and other photosensitive molecules. They serve to capture energy in...

Lim Kinases - Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembl...

Lipocalin 1 - A lipocalin that was orignally characterized from human TEARS. It is expressed primarily in the LACR...

Lipocalins - A diverse family of extracellular proteins that bind to small hydrophobic molecules. They were origi...

Lipoprotein(a) - A lipoprotein that resembles the LOW-DENSITY LIPOPROTEINS but with an extra protein moiety, APOPROTE...

Lipoproteins - Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They ar...

Lipoproteins, HDL - A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL l...

Lipoproteins, HDL2 - Low-density subclass of the high-density lipoproteins, with particle sizes between 8 to 13 nm....

Lipoproteins, HDL3 - Intermediate-density subclass of the high-density lipoproteins, with particle sizes between 7 to 8 n...

Lipoproteins, IDL - A mixture of very-low-density lipoproteins (VLDL), particularly the triglyceride-poor VLDL, with slo...

Lipoproteins, LDL - A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core ...

Lipoproteins, VLDL - A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core ...

Lipoprotein-X - An abnormal lipoprotein present in large amounts in patients with obstructive liver diseases such as...

Lipoxygenase - An enzyme of the oxidoreductase class that catalyzes reactions between linoleate and other fatty aci...

Lithostathine - The proteinaceous component of the pancreatic stone in patients with PANCREATITIS....

Long-Acting Thyroid Stimulator - An immunoglobulin G, often found in the blood of hyperthyroid individuals. It stimulates the thyroid...

L-Selectin - Cell adhesion molecule and CD antigen that serves as a homing receptor for lymphocytes to lymph node...

Luciferases - Enzymes that oxidize certain LUMINESCENT AGENTS to emit light (PHYSICAL LUMINESCENCE). The luciferas...

Luciferases, Bacterial - Luciferases from BACTERIA such as PHOTOBACTERIUM; VIBRIO; and PHOTORHABDUS....

Luciferases, Firefly - Luciferases from FIREFLIES, usually Photinus, that oxidizes FIREFLY LUCIFERIN to cause emission of P...

Luciferases, Renilla - Luciferases from RENILLA that oxidizes certain LUMINESCENT AGENTS to cause emission of PHOTONS....

Luminescent Proteins - Proteins which are involved in the phenomenon of light emission in living systems. Included are the ...

Lupus Coagulation Inhibitor - An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMAT...

Lymphocyte Antigen 96 - A secreted protein that associates with TOLL-LIKE RECEPTOR 4 and is essential for receptor recogniti...

Lymphocyte Function-Associated Antigen-1 - An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises t...

Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell developmen...

Lymphoid Enhancer-Binding Factor 1 - A T-cell factor that plays an essential role in EMBRYONIC DEVELOPMENT....

Lymphokines - Soluble protein factors generated by activated lymphocytes that affect other cells, primarily those ...

Lymphotoxin alpha1, beta2 Heterotrimer - A heterotrimer complex consisting of one molecule of LYMPHOTOXIN-ALPHA and two molecules of the LYMP...

Lymphotoxin beta Receptor - A member of the tumor necrosis factor receptor superfamily. It has specificity for LYMPHOTOXIN ALPHA...

Lymphotoxin-alpha - A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin...

Lymphotoxin-beta - A membrane-bound tumor necrosis family member found primarily on LYMPHOCYTES. It can form a heterotr...

Lypressin - The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VA...

Lysosomal-Associated Membrane Protein 1 - An abundant lysosomal-associated membrane protein that has been found to shuttle between LYSOSOMES; ...

Lysosomal-Associated Membrane Protein 2 - An abundant lysosomal-associated membrane protein that has been found to shuttle between LYSOSOMES; ...

Lysosome-Associated Membrane Glycoproteins - Ubiquitously expressed integral membrane glycoproteins found in the LYSOSOME....

Macroglobulins - Serum globulins with high molecular weight. (Dorland, 28th ed)...

Macrophage Colony-Stimulating Factor - A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The comp...

Macrophage Inflammatory Proteins - Heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Orig...

Macrophage Migration-Inhibitory Factors - Proteins released by sensitized LYMPHOCYTES and possibly other cells that inhibit the migration of M...

Macrophage-1 Antigen - An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11...

Macrophage-Activating Factors - Factors secreted by stimulated lymphocytes that prime macrophages to become nonspecifically cytotoxi...

MADS Domain Proteins - A superfamily of proteins that share a highly conserved MADS domain sequence motif. The term MADS re...

Maf Transcription Factors - Maf transcription factors are a family of basic-leucine zipper transcription factors that are closel...

Maf Transcription Factors, Large - A family of high molecular weight Maf transcription factors that contain distinct activation domains...

Maf Transcription Factors, Small - A family of Maf Transcription Factors that lack activation domains. Small Maf proteins function as t...

MafB Transcription Factor - A large maf protein that regulates HINDBRAIN development, contributes to CELL DIFFERENTIATION of MON...

MafF Transcription Factor - A small maf protein that forms dimers with NRF1 protein; NRF2 PROTEIN; and P45 NF-E2 PROTEIN. MafF c...

MafG Transcription Factor - MafG is a ubiquitously expressed small maf protein that is involved in CELL DIFFERENTIATION of ERYTH...

MafK Transcription Factor - A small Maf protein involved in differentiation of ERYTHROID CELLS. MafK was originally described as...

Magainins - A class of antimicrobial peptides discovered in the skin of XENOPUS LAEVIS. They kill bacteria by pe...

Mannose-Binding Lectin - A specific mannose-binding member of the collectin family of lectins. It binds to carbohydrate group...

Mannose-Binding Lectins - A subclass of lectins that are specific for CARBOHYDRATES that contain MANNOSE....

Mannose-Binding Protein-Associated Serine Proteases - Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed...

MAP Kinase Kinase 1 - An abundant 43-kDa mitogen-activated protein kinase kinase subtype with specificity for MITOGEN-ACTI...

MAP Kinase Kinase 2 - A 44 kDa mitogen-activated protein kinase kinase with specificity for MITOGEN-ACTIVATED PROTEIN KINA...

MAP Kinase Kinase 3 - A mitogen-activated protein kinase kinase with specificity for a subset of P38 MITOGEN-ACTIVATED PR...

MAP Kinase Kinase 4 - A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES...

MAP Kinase Kinase 5 - A mitogen-activated protein kinase kinase with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 7....

MAP Kinase Kinase 6 - A mitogen-activated protein kinase kinase with specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES...

MAP Kinase Kinase 7 - A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES...

MAP Kinase Kinase Kinase 1 - A 195-kDa MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It is found locali...

MAP Kinase Kinase Kinase 2 - A 70-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 5. It is activated during t...

MAP Kinase Kinase Kinase 3 - A 70-kDa MAPK kinase kinase with specificity for MAP KINASE KINASE 5....

MAP Kinase Kinase Kinase 4 - A 180-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 4 and MAP KINASE KINASE 6....

MAP Kinase Kinase Kinase 5 - A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specif...

MAP Kinase Kinase Kinases - Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that ...

Matrix Attachment Region Binding Proteins - Proteins that bind to the MATRIX ATTACHMENT REGIONS of DNA....

Matrix Metalloproteinases, Membrane-Associated - Matrix metalloproteinases that are associated with the CELL MEMBRANE, either through transmembrane d...

Maturation-Promoting Factor - Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meios...

MCM1 Protein - A sequence-specific DNA-binding protein that plays an essential role as a global regulator of yeast ...

Mediator Complex - A large protein complex which acts as a signaling adaptor protein that allows communication between ...

Mediator Complex Subunit 1 - A mediator complex subunit that is believed to play a key role in the coactivation of nuclear recept...

Megacins - Bacteriocins elaborated by mutant strains of Bacillus megaterium. They are protein or protein-lipopo...

Melanocortins - Peptides derived from pro-opiomelanocortin (POMC) which can stimulate MELANOCYTES or CORTICOTROPHS. ...

Melanocyte-Stimulating Hormones - Peptides with the ability to stimulate pigmented cells MELANOCYTES in mammals and MELANOPHORES in lo...

Melitten - Basic polypeptide from the venom of the honey bee (Apis mellifera). It contains 26 amino acids, has ...

Membrane Fusion Proteins - Proteins that catalyze MEMBRANE FUSION....

Membrane Glycoproteins - Glycoproteins found on the membrane or surface of cells....

Membrane Proteins - Proteins which are found in membranes including cellular and intracellular membranes. They consist o...

Membrane Transport Proteins - Membrane proteins whose primary function is to facilitate the transport of molecules across a biolog...

Merozoite Surface Protein 1 - A surface protein found on Plasmodium species which induces a T-cell response. The antigen is polymo...

Metallochaperones - A family of soluble metal binding proteins that are involved in the intracellular transport of speci...

Metalloproteins - Proteins that have one or more tightly bound metal ions forming part of their structure. (Dorland, 2...

Metallothionein - A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver...

Methemalbumin - A 1:1 molar complex of heme or hematin and albumin formed after the dissociation of methemoglobin in...

Methionine Sulfoxide Reductases - Reductases that catalyze the reaction of peptide-L-methionine -S-oxide + thioredoxin to produce pept...

Methyl-CpG-Binding Protein 2 - A DNA-binding protein that interacts with methylated CPG ISLANDS. It plays a role in repressing GENE...

Methylenetetrahydrofolate Reductase (NADPH2) - A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofo...

Metmyoglobin - Myoglobin which is in the oxidized ferric or hemin form. The oxidation causes a change in color from...

Microfilament Proteins - Filaments which are composed primarily of actin and found in the cytoplasmic matrix of almost all ce...

Microphthalmia-Associated Transcription Factor - A basic helix-loop-helix leucine zipper transcription factor that regulates the CELL DIFFERENTIATION...

Microtubule Proteins - Proteins found in the microtubules....

Microtubule-Associated Proteins - High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain c...

Milk Proteins - The major protein constituents of milk are CASEINS and whey proteins such as LACTALBUMIN and LACTOGL...

Mitochondrial ADP, ATP Translocases - A class of nucleotide translocases found abundantly in mitochondria that function as integral compon...

Mitochondrial Membrane Transport Proteins - Proteins involved in the transport of specific substances across the membranes of the MITOCHONDRIA....

Mitochondrial Proteins - Proteins encoded by the mitochondrial genome or proteins encoded by the nuclear genome that are impo...

Mitochondrial Proton-Translocating ATPases - Proton-translocating ATPases responsible for ADENOSINE TRIPHOSPHATE synthesis in the MITOCHONDRIA. T...

Mitogen-Activated Protein Kinase 1 - A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell ...

Mitogen-Activated Protein Kinase 10 - A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a ...

Mitogen-Activated Protein Kinase 3 - A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulatio...

Mitogen-Activated Protein Kinase 6 - A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increa...

Mitogen-Activated Protein Kinase 7 - A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress...

Mitogen-Activated Protein Kinase 8 - A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokin...

Mitogen-Activated Protein Kinase 9 - A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokin...

Mitogen-Activated Protein Kinase Kinases - A serine-threonine protein kinase family whose members are components in protein kinase cascades act...

Mitogen-Activated Protein Kinase Phosphatases - A subcategory of phosphohydrolases that are specific for MITOGEN-ACTIVATED PROTEIN KINASES. They pla...

Mitogen-Activated Protein Kinases - A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein ...

Molecular Chaperones - A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and t...

Molybdoferredoxin - A non-heme iron-sulfur protein isolated from Clostridium pasteurianum and other bacteria. It is a co...

Monocarboxylic Acid Transporters - A family of proteins involved in the transport of monocarboxylic acids such as LACTIC ACID and PYRUV...

Monocyte Chemoattractant Proteins - Chemokines that are chemoattractants for monocytes. These CC chemokines (cysteines adjacent) number ...

Monokines - Soluble mediators of the immune response that are neither antibodies nor complement. They are produc...

Monomeric Clathrin Assembly Proteins - A subclass of clathrin assembly proteins that occur as monomers....

Monomeric GTP-Binding Proteins - A class of monomeric, low molecular weight (20-25 kDa) GTP-binding proteins that regulate a variety ...

Monosaccharide Transport Proteins - A large group of membrane transport proteins that shuttle MONOSACCHARIDES across CELL MEMBRANES....

Motilin - A peptide of about 22-amino acids isolated from the DUODENUM. At low pH it inhibits gastric motor ac...

mRNA Cleavage and Polyadenylation Factors - Factors that are involved in directing the cleavage and POLYADENYLATION of the of MESSENGER RNA near...

MSH Release-Inhibiting Hormone - A hypothalamic tripeptide, enzymatic degradation product of OXYTOCIN, that inhibits the release of M...

MSX1 Transcription Factor - A homeodomain protein that interacts with TATA-BOX BINDING PROTEIN. It represses GENETIC TRANSCRIPTI...

Mucin 5AC - A gel-forming mucin that is primarily found on the surface of gastric epithelium and in the RESPIRAT...

Mucin-1 - Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as we...

Mucin-2 - A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing...

Mucin-3 - A membrane-bound mucin subtype that is primarily found in INTESTINAL MUCOSA. Two closely-related sub...

Mucin-4 - A transmembrane mucin that is found in a broad variety of epithelial tissue. Mucin-4 may play a role...

Mucin-5B - A gel-forming mucin that is predominantly expressed by submucosal glands of airway tissues and the S...

Mucin-6 - A gel-forming mucin that is predominantly associated with the gastric epithelium....

Mucins - High molecular weight mucoproteins that form a protective biofilm on the surface of EPITHELIAL CELLS...

Mucoproteins - Conjugated proteins in which mucopolysaccharides are combined with proteins. The mucopolysaccharide ...

Multidrug Resistance-Associated Proteins - A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic su...

Munc18 Proteins - A family of proteins involved in intracellular membrane trafficking. They interact with SYNTAXINS an...

Muromonab-CD3 - Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell dep...

Muscle Proteins - The protein constituents of muscle, the major ones being ACTINS and MYOSINS. More than a dozen acces...

Mutant Chimeric Proteins - Proteins produced from GENES that have mutated by the fusing of protein coding regions of more than ...

Mutant Proteins - Proteins produced from GENES that have acquired MUTATIONS....

MutS DNA Mismatch-Binding Protein - A methyl-directed mismatch DNA REPAIR protein that has weak ATPASE activity. MutS was originally des...

MutS Homolog 2 Protein - MutS homolog 2 protein is found throughout eukaryotes and is a homolog of the MUTS DNA MISMATCH-BIND...

Myelin Basic Proteins - A group of 7 proteins produced from a single gene by alternate splicing found in central and periphe...

Myelin P0 Protein - A protein that accounts for more than half of the peripheral nervous system myelin protein. The extr...

Myelin P2 Protein - A positively charged protein found in peripheral nervous system myelin. Sensitive immunological tech...

Myelin Proteins - Proteins found in the myelin sheath. The major proteins of central nervous system myelin include: MY...

Myelin Proteolipid Protein - A myelin protein that is the major component of the organic solvent extractable lipoprotein complexe...

Myelin-Associated Glycoprotein - A myelin protein found in the periaxonal membrane of both the central and peripheral nervous systems...

Myeloid Differentiation Factor 88 - An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1...

Myeloid-Lymphoid Leukemia Protein - Myeloid-lymphoid leukemia protein is a transcription factor that maintains high levels of HOMEOTIC G...

Myeloma Proteins - Abnormal immunoglobulins characteristic of MULTIPLE MYELOMA....

MyoD Protein - A myogenic regulatory factor that controls myogenesis. Though it is not clear how its function diffe...

Myogenic Regulatory Factor 5 - A SKELETAL MUSCLE-specific transcription factor that contains a basic HELIX-LOOP-HELIX MOTIF. It pla...

Myogenic Regulatory Factors - A family of muscle-specific transcription factors which bind to DNA in control regions and thus regu...

Myogenin - A myogenic regulatory factor that controls myogenesis. Myogenin is induced during differentiation of...

Myoglobin - A conjugated protein which is the oxygen-transporting pigment of muscle. It is made up of one globin...

Myosin Heavy Chains - The larger subunits of MYOSINS. The heavy chains have a molecular weight of about 230 kDa and each h...

Myosin Light Chains - The smaller subunits of MYOSINS that bind near the head groups of MYOSIN HEAVY CHAINS. The myosin l...

Myosin Subfragments - Parts of the myosin molecule resulting from cleavage by proteolytic enzymes (PAPAIN; TRYPSIN; or CHY...

Myosin Type I - A subclass of myosins found generally associated with actin-rich membrane structures such as filopod...

Myosin Type II - The subfamily of myosin proteins that are commonly found in muscle fibers. Myosin II is also involve...

Myosin Type III - A subclass of myosins originally found in the photoreceptor of DROSOPHILA. The heavy chains can occu...

Myosin Type IV - A subclass of myosin found in ACANTHAMOEBA. It is a non-filamentous myosin containing a single 180-k...

Myosin Type V - A subclass of myosin involved in organelle transport and membrane targeting. It is abundantly found ...

Myosin-Light-Chain Kinase - An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain...

Myosins - A diverse superfamily of proteins that function as translocating proteins. They share the common cha...

Myostatin - A growth differentiation factor that is a potent inhibitor of SKELETAL MUSCLE growth. It may play a ...

NADH Dehydrogenase - A flavoprotein and iron sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD...

NADPH Oxidase - A flavoprotein enzyme that catalyzes the univalent reduction of OXYGEN using NADPH as an electron do...

Nafarelin - A potent synthetic agonist of GONADOTROPIN-RELEASING HORMONE with 3-(2-naphthyl)-D-alanine substitut...

Natriuretic Peptide, Brain - A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MY...

Natural Cytotoxicity Triggering Receptor 1 - A 46-kD stimulatory receptor found on resting and activated NATURAL KILLER CELLS. It has specificity...

Natural Cytotoxicity Triggering Receptor 2 - A 44-kD stimulatory receptor found on activated NATURAL KILLER CELLS. It has specificity for VIRAL H...

Natural Cytotoxicity Triggering Receptor 3 - A 30 kDa stimulatory receptor found on resting and activated NATURAL KILLER CELLS....

nef Gene Products, Human Immunodeficiency Virus - Proteins encoded by the NEF GENES of the HUMAN IMMUNODEFICIENCY VIRUS....

Neoplasm Proteins - Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or pr...

Nephroblastoma Overexpressed Protein - A CCN protein family member found at high levels in NEPHROBLASTOMA cells. It is found both intracell...

Nerve Growth Factor - NERVE GROWTH FACTOR is the first of a series of neurotrophic factors that were found to influence th...

Nerve Growth Factors - Factors which enhance the growth potentialities of sensory and sympathetic nerve cells....

Neural Cell Adhesion Molecule L1 - A member of the immunoglobulin superfamily of neuronal cell adhesion molecules that is required for ...

Neural Cell Adhesion Molecules - Cell adhesion molecule involved in a diverse range of contact-mediated interactions among neurons, a...

Neuregulin-1 - A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 re...

Neuregulins - A family of peptides originally found as factors that stimulate the phosphorylation of the erbB-2 re...

Neurocalcin - A neuronal calcium sensor protein that is expressed as several isoforms and can interact with ACTIN;...

Neuroendocrine Secretory Protein 7B2 - An acidic protein found in the NEUROENDOCRINE SYSTEM that functions as a molecular chaperone for PRO...

Neurofibromin 1 - A protein found most abundantly in the nervous system. Defects or deficiencies in this protein are a...

Neurofibromin 2 - A membrane protein homologous to the ERM (Ezrin-Radixin-Moesin) family of cytoskeleton-associated pr...

Neurofilament Proteins - Type III intermediate filament proteins that assemble into neurofilaments, the major cytoskeletal el...

Neurogranin - A BRAIN-specific substrate for PROTEIN KINASE C that binds CALMODULIN and is involved in regulation ...

Neurokinin A - A mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in s...

Neurokinin B - A mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in s...

Neuroleukin - Neuronal growth factor and lymphokine product of lectin-stimulated T-cells which induces immunoglobu...

Neuronal Apoptosis-Inhibitory Protein - An inhibitor of apoptosis protein that was initially identified during analysis of CHROMOSOME DELETI...

Neuronal Calcium-Sensor Proteins - A family of intracellular calcium-sensing proteins found predominately in NEURONS and PHOTORECEPTOR ...

Neuropeptide Y - A 36-amino acid peptide present in many organs and in many sympathetic noradrenergic neurons. It has...

Neuropeptides - Peptides released by NEURONS as intercellular messengers. Many neuropeptides are also hormones relea...

Neurophysins - Carrier proteins for OXYTOCIN and VASOPRESSIN. They are polypeptides of about 10-kDa, synthesized in...

Neuropilin-1 - Dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and axona...

Neuropilin-2 - Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isofor...

Neuropilins - Neuropilins are 140-kDa vertebrate cell surface receptors that bind neuronal guidance molecules duri...

Neurotensin - A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hyp...

Neurotransmitter Transport Proteins - Membrane transport proteins found predominately in NEURONS and neuroendocrine cells that facilitate ...

Neurotrophin 3 - A neurotrophic factor involved in regulating the survival of visceral and proprioceptive sensory neu...

Neurturin - A glial cell line-derived neurotrophic factor ligand that is specific for the GFRA2 RECEPTOR. Neurtu...

NFATC Transcription Factors - A family of transcription factors characterized by the presence of highly conserved calcineurin- and...

NF-E2 Transcription Factor - A basic-leucine zipper transcription factor that regulates GLOBIN gene expression and is related to ...

NF-E2 Transcription Factor, p45 Subunit - A tissue-specific subunit of NF-E2 transcription factor that interacts with small MAF PROTEINS to re...

NF-E2-Related Factor 1 - A basic-leucine zipper transcription factor that is involved in regulating inflammatory responses, M...

NF-E2-Related Factor 2 - A basic-leucine zipper transcription factor that was originally described as a transcriptional regul...

NFI Transcription Factors - Transcription factors that were originally identified as site-specific DNA-binding proteins essentia...

NF-kappa B - Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many dif...

NF-kappa B p50 Subunit - A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105...

NF-kappa B p52 Subunit - A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p100...

Nisin - A 34-amino acid polypeptide antibiotic produced by Streptococcus lactis. It has been used as a food ...

Nitrate Reductase (NAD(P)H) - An iron-sulfur and MOLYBDENUM containing FLAVOPROTEIN that catalyzes the oxidation of nitrite to nit...

Nitrate Reductase (NADH) - An NAD-dependent enzyme that catalyzes the oxidation of nitrite to nitrate. It is a FLAVOPROTEIN tha...

Nitrate Reductase (NADPH) - An enzyme that catalyzes the oxidation of nitrite to nitrate in the presence of NADP+. It is a FLAVO...

NK Cell Lectin-Like Receptor Subfamily A - An inhibitory subclass of NK cell lectin-like receptors that interacts with CLASS I MAJOR HISTOCOMPA...

NK Cell Lectin-Like Receptor Subfamily B - A subclass of NK cell lectin-like receptors that includes both inhibitory and stimulatory members....

NK Cell Lectin-Like Receptor Subfamily C - A subclass of NK cell lectin-like receptors that associates with members of NK CELL LECTIN-LIKE RECE...

NK Cell Lectin-Like Receptor Subfamily D - A subclass of NK cell lectin-like receptors that associates with a variety of members of NK CELL LEC...

NK Cell Lectin-Like Receptor Subfamily K - An activating NK cell lectin-like receptor subfamily that regulates immune responses to INFECTION an...

Nod Signaling Adaptor Proteins - Cytosolic signaling adaptor proteins that were initially discovered by their role in the innate immu...

Nod1 Signaling Adaptor Protein - A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bact...

Nod2 Signaling Adaptor Protein - A NOD signaling adaptor protein that contains two C-terminal leucine-rich domains which recognize ba...

Nodal Protein - The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally d...

Nodal Signaling Ligands - Members of the transforming growth factor superfamily that play a role in pattern formation and diff...

Non-Fibrillar Collagens - A family of structurally-related short-chain collagens that do not form large fibril bundles....

Nonheme Iron Proteins - Proteins, usually acting in oxidation-reduction reactions, containing iron but no porphyrin groups. ...

Nonmuscle Myosin Type IIA - A nonmuscle isoform of myosin type II found predominantly in platelets, lymphocytes, neutrophils and...

Nonmuscle Myosin Type IIB - A nonmuscle isoform of myosin type II found predominantly in neuronal tissue....

Nonsuppressible Insulin-Like Activity - A blood protein (NSILA) which mimics the biological activity of insulin in serum, but is not suppres...

Norepinephrine Plasma Membrane Transport Proteins - Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of no...

Nuclear Cap-Binding Protein Complex - A heterodimeric protein complex of RNA cap-binding proteins, which binds with high affinity to the 5...

Nuclear Factor 45 Protein - A protein subunit that takes part in forming nuclear factor 90 protein complexes....

Nuclear Factor 90 Proteins - A family of double-stranded RNA-binding proteins that are related to NFATC TRANSCRIPTION FACTORS. In...

Nuclear Matrix-Associated Proteins - A broad category of nuclear proteins that are components of or participate in the formation of the N...

Nuclear Pore Complex Proteins - Proteins that form the structure of the NUCLEAR PORE. They are involved in active, facilitated and p...

Nuclear Proteins - Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conju...

Nuclear Receptor Coactivator 1 - A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and ...

Nuclear Receptor Coactivator 2 - A transcription factor that partners with ligand bound GLUCOCORTICOID RECEPTORS and ESTROGEN RECEPTO...

Nuclear Receptor Coactivator 3 - A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE RECEPTORS. I...

Nuclear Receptor Coactivators - Proteins that enhance gene expression when associated with ligand bound activated NUCLEAR RECEPTORS....

Nuclear Receptor Co-Repressor 1 - A nuclear protein that regulates the expression of genes involved in a diverse array of processes re...

Nuclear Receptor Co-Repressor 2 - A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMON...

Nuclear Receptor Subfamily 1, Group D, Member 1 - A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FA...

Nuclear Receptor Subfamily 1, Group F, Member 1 - A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FA...

Nuclear Receptor Subfamily 1, Group F, Member 2 - An orphan nuclear receptor that is expressed at high levels in neuronal tissues, the RETINA; EPIDIDY...

Nuclear Receptor Subfamily 1, Group F, Member 3 - An orphan nuclear receptor found in the THYMUS where it plays a role in regulating the development a...

Nuclear Receptor Subfamily 2, Group C, Member 1 - A DNA-binding orphan nuclear receptor that has specificity for directly repeated (DR) AGGTCA sequenc...

Nuclear Receptor Subfamily 2, Group C, Member 2 - An orphan nuclear receptor that has specificity for hormone response elements found in the promoters...

Nuclear Receptor Subfamily 4, Group A, Member 1 - An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene f...

Nuclear Receptor Subfamily 4, Group A, Member 2 - An orphan nuclear receptor that is found at high levels in BRAIN tissue. The protein is believed to ...

Nuclear Receptor Subfamily 4, Group A, Member 3 - An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor family...

Nuclear Receptor Subfamily 6, Group A, Member 1 - An orphan nuclear receptor expressed mainly in the GERM CELLS of GONADS. It functions as a transcrip...

Nuclear Respiratory Factor 1 - A transcription factor that controls the expression of variety of proteins including CYTOCHROME C an...

Nuclear Respiratory Factors - A family of transcription factors that control expression of a variety of nuclear GENES encoding pro...

Nucleobase Transport Proteins - Proteins involved in the transport of nucleobases such as PYRIMIDINES and PURINES across membranes....

Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins - A broad class of proteins involved in the transport of nucleobases, NUCLEOSIDES; NUCLEOTIDES; and NU...

Nucleocapsid Proteins - Viral proteins found in either the NUCLEOCAPSID or the viral core (VIRAL CORE PROTEINS)....

Nucleocytoplasmic Transport Proteins - Proteins involved in the process of transporting molecules in and out the cell nucleus. Included her...

Nucleoplasmins - A family of histone molecular chaperones that play roles in sperm CHROMATIN decondensation and CHROM...

Nucleoproteins - Proteins conjugated with nucleic acids....

Nucleoside Transport Proteins - Proteins involved in the transport of NUCLEOSIDES across cellular membranes....

Nucleosome Assembly Protein 1 - A histone chaperone that facilitates nucleosome assembly by mediating the formation of the histone o...

Nucleosomes - The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA ...

Nucleotide Transport Proteins - Proteins involved in the transport of NUCLEOTIDES across cellular membranes....

Octamer Transcription Factor-1 - A ubiquitously expressed octamer transcription factor that regulates GENETIC TRANSCRIPTION of SMALL ...

Octamer Transcription Factor-2 - An octamer transcription factor expressed primarily in B-LYMPHOCYTES and the developing CENTRAL NERV...

Octamer Transcription Factor-3 - An octamer transcription factor that is expressed primarily in totipotent embryonic STEM CELLS and G...

Octamer Transcription Factor-6 - An octamer transcription factor that plays an important role in the MYELIN SHEATH development by SCH...

Octamer Transcription Factors - A family of POU domain factors that bind the octamer motif ATTTGCAT in enhancer and PROMOTER REGIONS...

Olfactory Marker Protein - A ubiquitous, cytoplasmic protein found in mature OLFACTORY RECEPTOR NEURONS of all VERTEBRATES. It ...

Oligoclonal Bands - Multiple protein bands serving as markers of specific ANTIBODIES and detected by ELECTROPHORESIS of ...

omega-Agatoxin IVA - A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIU...

omega-Crystallins - A type of crystallin that has been found in the lens (LENS, CRYSTALLINE) of certain species of MOLLU...

Oncogene Protein gp140(v-fms) - Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcom...

Oncogene Protein p21(ras) - Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can ...

Oncogene Protein p55(v-myc) - Transforming protein coded by myc oncogenes. The v-myc protein has been found in several replication...

Oncogene Protein p65(gag-jun) - Transforming protein coded by jun oncogenes (GENES, JUN). This is a gag-onc fusion protein of about ...

Oncogene Protein pp60(v-src) - A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transfor...

Oncogene Protein tpr-met - The GENETIC TRANSLATION product from a GENE FUSION between a sequence from the tpr protein gene on t...

Oncogene Protein v-akt - A viral oncoprotein originally isolated from a murine T CELL LYMPHOMA infected with the acutely tran...

Oncogene Protein v-cbl - An oncoprotein from the Cas NS-1 murine retrovirus that induces pre- B-CELL LYMPHOMA and MYELOID LEU...

Oncogene Protein v-crk - A signal transducing adaptor protein that is encoded by the crk ONCOGENE from TYPE C AVIAN RETROVIRU...

Oncogene Protein v-maf - An oncogene protein that was originally isolated from a spontaneous musculo-aponeurotic FIBROSARCOMA...

Oncogene Proteins - Proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and anot...

Oncogene Proteins v-abl - Transforming proteins encoded by the abl oncogenes. Oncogenic transformation of c-abl to v-abl occur...

Oncogene Proteins v-erbA - Transforming proteins encoded by erbA oncogenes from the avian erythroblastosis virus. They are trun...

Oncogene Proteins v-erbB - Transforming proteins encoded by erbB oncogenes from the avian erythroblastosis virus. The protein i...

Oncogene Proteins v-fos - Transforming proteins coded by fos oncogenes. These proteins have been found in the Finkel-Biskis-Ji...

Oncogene Proteins v-mos - Transforming proteins coded by mos oncogenes. The v-mos proteins were originally isolated from the M...

Oncogene Proteins v-myb - Transforming proteins coded by myb oncogenes. Transformation of cells by v-myb in conjunction with v...

Oncogene Proteins v-raf - A family of transforming proteins isolated from retroviruses such as MOUSE SARCOMA VIRUSES. They are...

Oncogene Proteins v-rel - Transforming proteins coded by rel oncogenes. The v-rel protein competes with rel-related proteins a...

Oncogene Proteins v-sis - Transforming proteins coded by sis oncogenes. Transformation of cells by v-sis is related to its int...

Oncogene Proteins, Fusion - The GENETIC TRANSLATION products of the fusion between an ONCOGENE and another gene. The latter may ...

Oncogene Proteins, Viral - Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and ...

Oncostatin M - A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironme...

Oncostatin M Receptor beta Subunit - An ONCOSTATIN M-specific receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the ONC...

Onecut Transcription Factors - A family of transcription factors that contain a single cut domain and a divergent homeodomain. They...

Opioid Peptides - The endogenous peptides with opiate-like activity. The three major classes currently recognized are ...

Opsins - Photosensitive proteins in the membranes of PHOTORECEPTOR CELLS such as the rods and the cones. Opsi...

Opsonin Proteins - Proteins that bind to particles and cells to increase susceptibility to PHAGOCYTOSIS, especially ANT...

Organic Anion Transport Polypeptide C - An organic anion transporter found in human liver. It is capable of transporting a variety organic a...

Organic Anion Transport Protein 1 - A polyspecific transporter for organic cations found primarily in the kidney. It mediates the couple...

Organic Anion Transporters - Proteins involved in the transport of organic anions. They play an important role in the elimination...

Organic Anion Transporters, ATP-Dependent - A subclass of ORGANIC ANION TRANSPORTERS whose transport of organic anions is linked directly to the...

Organic Anion Transporters, Sodium-Dependent - A subclass of ORGANIC ANION TRANSPORTERS whose transport of organic anions is driven either directly...

Organic Anion Transporters, Sodium-Independent - A subclass of ORGANIC ANION TRANSPORTERS that do not rely directly or indirectly upon sodium ion gra...

Organic Cation Transport Proteins - A family of proteins involved in the transport of organic cations. They play an important role in th...

Organic Cation Transporter 1 - An organic cation transporter found in kidney. It is localized to the basal lateral membrane and is ...

Origin Recognition Complex - The origin recognition complex is a multi-subunit DNA-binding protein that initiates DNA REPLICATION...

Ornipressin - A synthetic analog of vasopressin with ORNITHINE substitution at residue 8 of the cyclic nonapeptide...

Orphan Nuclear Receptors - A broad category of receptor-like proteins that may play a role in transcriptional-regulation in the...

Osteocalcin - Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES....

Osteonectin - Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in th...

Osteopontin - A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabo...

Osteoprotegerin - A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It i...

Otx Transcription Factors - A family of VERTEBRATE homeodomain proteins that share homology with orthodenticle protein, Drosophi...

Ovalbumin - An albumin obtained from the white of eggs. It is a member of the serpin superfamily....

Ovomucin - A heterogeneous mixture of glycoproteins responsible for the gel structure of egg white. It has tryp...

OX40 Ligand - A membrane-bound tumor necrosis family member that is expressed on activated antigen-presenting cell...

Oxyhemoglobins - A compound formed by the combination of hemoglobin and oxygen. It is a complex in which the oxygen i...

p120 GTPase Activating Protein - A 120-kDa RAS GTPase-activating protein that binds to tyrosine phosphoproteins through its SH2 domai...

p21-Activated Kinases - A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEIN...

p300-CBP Transcription Factors - A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E...

p38 Mitogen-Activated Protein Kinases - A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes includin...

Paired Box Transcription Factors - A family of transcription factors that control EMBRYONIC DEVELOPMENT within a variety of cell lineag...

Pancreatic Polypeptide - A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery...

Papillomavirus E7 Proteins - ONCOGENE PROTEINS from papillomavirus that deregulate the CELL CYCLE of infected cells and lead to N...

Paraproteins - Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraprot...

Parathyroid Hormone-Related Protein - A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activ...

Parvalbumins - Low molecular weight, calcium binding muscle proteins. Their physiological function is possibly rela...

PAX2 Transcription Factor - A paired box transcription factor that is essential for ORGANOGENESIS of the CENTRAL NERVOUS SYSTEM ...

PAX7 Transcription Factor - A paired box transcription factor that is involved in EMBRYONIC DEVELOPMENT of the CENTRAL NERVOUS S...

PAX9 Transcription Factor - A paired box transcription factor that is involved in ODONTOGENESIS....

Paxillin - Paxillin is a signal transducing adaptor protein for CELL MIGRATION that localizes primarily to FOCA...

Peanut Agglutinin - Lectin purified from peanuts (ARACHIS HYPOGAEA). It binds to poorly differentiated cells and termina...

Penicillin-Binding Proteins - Bacterial proteins that share the property of binding irreversibly to PENICILLINS and other ANTIBACT...

Peptide Elongation Factor 1 - Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent bind...

Peptide Elongation Factor 2 - Peptide Elongation Factor 2 catalyzes the translocation of peptidyl-tRNA from the A site to the P si...

Peptide Elongation Factor G - Peptide Elongation Factor G catalyzes the translocation of peptidyl-tRNA from the A to the P site of...

Peptide Elongation Factor Tu - A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A sit...

Peptide Elongation Factors - Protein factors uniquely required during the elongation phase of protein synthesis....

Peptide Initiation Factors - Protein factors uniquely required during the initiation phase of protein synthesis in GENETIC TRANSL...

Peptide PHI - A 27-amino acid peptide with histidine at the N-terminal and isoleucine amide at the C-terminal. The...

Peptide Termination Factors - Proteins that are involved in the peptide chain termination reaction (PEPTIDE CHAIN TERMINATION, TRA...

Peptones - Derived proteins or mixtures of cleavage products produced by the partial hydrolysis of a native pro...

Perforin - A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in sec...

Period Circadian Proteins - Circadian rhythm signaling proteins that influence circadian clock by interacting with other circadi...

Periplasmic Binding Proteins - Periplasmic proteins that scavenge or sense diverse nutrients. In the bacterial environment they usu...

Periplasmic Proteins - Proteins found in the PERIPLASM of organisms with cell walls....

Peroxisome Proliferator-Activated Receptors - TRANSCRIPTION FACTORS that are activated by ligands and heterodimerize with RETINOID X RECEPTORS and...

P-Glycoprotein - A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It s...

P-Glycoproteins - A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that...

PHEX Phosphate Regulating Neutral Endopeptidase - A membrane-bound metalloendopeptidase that may play a role in the degradation or activation of a var...

Phosphate Transport Proteins - Membrane proteins that are involved in the active transport of phosphate....

Phosphate-Binding Proteins - Proteins that bind to and are involved in the metabolism of phosphate ions....

Phosphatidylethanolamine Binding Protein - A ubiquitously found basic protein that binds to phosphatidylethanolamine and NUCLEOTIDES. It is an ...

Phosphoinositide Phospholipase C - A type C phospholipase with specificity towards PHOSPHATIDYLINOSITOLS that contain INOSITOL 1,4,5-TR...

Phospholipase C beta - A phosphoinositide phospholipase C subtype that is primarily regulated by its association with HETER...

Phospholipase C delta - A phosphoinositide phospholipase C subtype that is structurally defined by the presence of an N-term...

Phospholipase C gamma - A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. ...

Phospholipid Transfer Proteins - A ubiquitous family of proteins that transport PHOSPHOLIPIDS such as PHOSPHATIDYLINOSITOL and PHOSPH...

Phosvitin - An egg yolk phosphoglycoprotein which contains about 90% of the yolk protein phosphorus. It is synth...

Photoreceptors, Microbial - Light absorbing proteins and protein prosthetic groups found in certain microorganisms. Some microbi...

Photoreceptors, Plant - Plant proteins that mediate LIGHT SIGNAL TRANSDUCTION. They are involved in PHOTOTROPISM and other l...

Photosynthetic Reaction Center Complex Proteins - Protein complexes that take part in the process of PHOTOSYNTHESIS. They are found in the THYLAKOID M...

Photosystem I Protein Complex - A large multisubunit protein complex that is found in the THYLAKOID MEMBRANE. It uses light energy d...

Photosystem II Protein Complex - A large multisubunit protein complex found in the THYLAKOID MEMBRANE. It uses light energy derived f...

Phototropins - Blue-light receptors that regulate a range of physiological responses in PLANTS. Examples include: P...

Phycobiliproteins - Light harvesting proteins found in phycobilisomes....

Phycobilisomes - Light energy harvesting structures attached to the THYLAKOID MEMBRANES of CYANOBACTERIA and red alga...

Phycocyanin - The metal-free blue phycobilin pigment in a conjugated chromoprotein of blue-green algae. It functio...

Phycoerythrin - The metal-free red phycobilin pigment in a conjugated chromoprotein of red algae. It functions as a ...

Physalaemin - An oligopeptide isolated from the skin of Physalaemus fuscumaculatus, a South American frog. It is a...

Phytochrome - A blue-green biliprotein widely distributed in the plant kingdom....

Phytochrome A - The primary plant photoreceptor responsible for perceiving and mediating responses to far-red light....

Phytochrome B - A plant photo regulatory protein that exists in two forms that are reversibly interconvertible by LI...

Phytohemagglutinins - Mucoproteins isolated from the kidney bean (Phaseolus vulgaris); some of them are mitogenic to lymph...

PII Nitrogen Regulatory Proteins - A family of signal transducing adaptor proteins that control the METABOLISM of NITROGEN. They are pr...

Pituitary Adenylate Cyclase-Activating Polypeptide - A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP le...

Pituitary Hormone Release Inhibiting Hormones - Polypeptide hormones produced in the hypothalamus which inhibit the release of pituitary hormones. U...

Pituitary Hormone-Releasing Hormones - Peptides, natural or synthetic, that stimulate the release of PITUITARY HORMONES. They were first is...

Placental Lactogen - A polypeptide hormone of approximately 25 kDa that is produced by the SYNCYTIOTROPHOBLASTS of the PL...

Plakins - A family of related proteins that associate with cytoskeletal elements and junctional complexes at I...

Plakophilins - Members of the armadillo family of proteins that are found in DESMOSOMES and interact with various p...

Plant Lectins - Protein or glycoprotein substances of plant origin that bind to sugar moieties in cell walls or memb...

Plant Proteins - Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include protein...

Plant Viral Movement Proteins - Viral proteins that facilitate the movement of viruses between plant cells by means of PLASMODESMATA...

Plantibodies - Recombinant antibodies produced in TRANSGENIC PLANTS. The plants serve as BIOREACTORS to produce the...

Plasma Membrane Calcium-Transporting ATPases - Calcium-transporting ATPases found on the PLASMA MEMBRANE that catalyze the active transport of CALC...

Plasma Membrane Neurotransmitter Transport Proteins - A family of neurotransmitter transporter proteins that facilitate NEUROTRANSMITTER reuptake into PRE...

Plasminogen - Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,00...

Plasminogen Activator Inhibitor 1 - A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasm...

Plasminogen Activator Inhibitor 2 - Member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasmin...

Plasminogen Activators - A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are conc...

Plasminogen Inactivators - Important modulators of the activity of plasminogen activators. Four inhibitors, all belonging to th...

Plastocyanin - A copper-containing plant protein that is a fundamental link in the electron transport chain of gree...

Plastoquinol-Plastocyanin Reductase - A component of the CYTOCHROME B6F COMPLEX, this enzyme catalyzes the oxidation of plastoquinol-1 to ...

Platelet Factor 3 - A phospholipid from the platelet membrane that contributes to the blood clotting cascade by forming ...

Platelet Factor 4 - A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size o...

Platelet Glycoprotein GPIb-IX Complex - Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at ...

Platelet Glycoprotein GPIIb-IIIa Complex - Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an int...

Platelet Membrane Glycoprotein IIb - Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN B...

Platelet Membrane Glycoproteins - Surface glycoproteins on platelets which have a key role in hemostasis and thrombosis such as platel...

Platelet-Derived Growth Factor - Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when pla...

Plectin - A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE...

Pokeweed Mitogens - Proteins isolated from the roots of the pokeweed, Phytolacca americana, that agglutinate some erythr...

pol Gene Products, Human Immunodeficiency Virus - Proteins encoded by the POL GENE of the HUMAN IMMUNODEFICIENCY VIRUS....

Pol1 Transcription Initiation Complex Proteins - Factors that form a preinitiation complex at promoters that are specifically transcribed by RNA POLY...

Poly(A)-Binding Protein I - A poly(A) binding protein that has a variety of functions such as mRNA stabilization and protection ...

Poly(A)-Binding Protein II - A poly(A) binding protein that is involved in promoting the extension of the poly A tails of MRNA. T...

Poly(A)-Binding Proteins - Proteins that bind to the 3' polyadenylated region of MRNA. When complexed with RNA the proteins ser...

Polymyxin B - A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypepti...

Polymyxins - Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by...

Polyproteins - Proteins which are synthesized as a single polymer and then cleaved into several distinct proteins....

Polypyrimidine Tract-Binding Protein - A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. ...

Polyubiquitin - An oligomer formed from the repetitive linking of the C-terminal glycine of one UBIQUITIN molecule ...

Pore Forming Cytotoxic Proteins - Proteins secreted from an organism which form membrane-spanning pores in target cells to destroy the...

Porins - Porins are protein molecules that were originally found in the outer membrane of GRAM-NEGATIVE BACTE...

Positive Transcriptional Elongation Factor B - A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT K...

Potassium Channels - Cell membrane glycoproteins that are selectively permeable to potassium ions. At least eight major g...

Potassium Channels, Calcium-Activated - Potassium channels whose activation is dependent on intracellular calcium concentrations....

Potassium Channels, Inwardly Rectifying - Potassium channels where the flow of K+ ions into the cell is greater than the outward flow....

Potassium Channels, Tandem Pore Domain - Potassium channels that contain two pores in tandem. They are responsible for baseline or leak curre...

Potassium Channels, Voltage-Gated - Potassium channel whose permeability to ions is extremely sensitive to the transmembrane potential d...

Potassium-Hydrogen Antiporters - Membrane proteins that allow the exchange of hydrogen ions for potassium ions across the cellular me...

POU Domain Factors - A family of transcription factors characterized by the presence of a bipartite DNA-binding domain kn...

PPAR alpha - A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR GAMMA is important to me...

PPAR delta - A nuclear transcription factor. It is activated by PROSTACYCLIN....

PPAR gamma - A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in re...

PPAR-beta - One of the PPAR nuclear transcription factors....

Prealbumin - A tetrameric protein, molecular weight between 50,000 and 70,000, consisting of 4 equal chains, and ...

Pre-B Cell Receptors - Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU I...

Precipitins - Antibodies which elicit IMMUNOPRECIPITATION when combined with antigen....

Pregnancy Proteins - Proteins produced by organs of the mother or the PLACENTA during PREGNANCY. These proteins may be pr...

Pregnancy-Associated alpha 2-Macroglobulins - Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high conce...

Pregnancy-Associated Plasma Protein-A - A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It ...

Pregnancy-Specific beta 1-Glycoproteins - Glycoproteins with the electrophoretic mobility of BETA-GLOBULINS, secreted by the placental TROPHOB...

Prekallikrein - A plasma protein which is the precursor of kallikrein. Plasma that is deficient in prekallikrein has...

Presenilin-1 - Integral membrane protein of Golgi and endoplasmic reticulum. Its homodimer is an essential componen...

Presenilin-2 - Integral membrane protein of Golgi and endoplasmic reticulum. Its homodimer is an essential componen...

Presenilins - Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes th...

Prions - Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC...

Procollagen - A biosynthetic precursor of collagen containing additional amino acid sequences at the amino-termina...

Profilins - A family of low molecular weight proteins that bind ACTIN and control actin polymerization. They are...

Progesterone-Binding Globulin - A glycoprotein migrating as alpha 1-globulin, molecular weight 70,000 to 120,000. The protein, which...

Proglucagon - The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE PEPTIDES. Progl...

Proinsulin - A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor o...

Prokaryotic Initiation Factor-1 - The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD...

Prokaryotic Initiation Factor-2 - The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD...

Prokaryotic Initiation Factor-3 - A prokaryotic initiation factor that plays a role in recycling of ribosomal subunits for a new round...

Prokaryotic Initiation Factors - Peptide initiation factors from prokaryotic organisms. Only three factors are needed for translatio...

Prolactin Release-Inhibiting Factors - A number of peptides with inhibitory activities on PROLACTIN release have been isolated from the HYP...

Prolactin-Releasing Hormone - A hypothalamic hormone that is synthesized as a precursor protein which is cleaved into two peptides...

Prolamins - A group of seed storage proteins restricted to the POACEAE family. They are rich in GLUTAMINE and PR...

Proliferating Cell Nuclear Antigen - Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is requir...

Pro-Opiomelanocortin - A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is a...

Properdin - A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COM...

Prostate-Specific Antigen - A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial c...

Prostatic Secretory Proteins - Proteins secreted by the prostate gland. The major secretory proteins from the human prostate gland ...

Protamine Kinase - An aspect of protein kinase (EC 2.7.1.37) in which serine residues in protamines and histones are ph...

Protamines - A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with n...

Protein C - A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomo...

Protein C Inhibitor - A member of the serpin family of proteins that is found in plasma and urine. It is dependent on hepa...

Protein Inhibitors of Activated STAT - A family of structurally related proteins that are constitutively expressed and that negatively regu...

Protein Isoforms - Different forms of a protein that may be produced from different GENES, or from the same gene by ALT...

Protein Phosphatase 2 - A phosphoprotein phosphatase subtype that is comprised of a catalytic subunit and two different regu...

Protein S - The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the ac...

Protein Subunits - Single chains of amino acids that are the units of multimeric PROTEINS. Multimeric proteins can be c...

Protein Tyrosine Phosphatase, Non-Receptor Type 1 - A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting moti...

Protein Tyrosine Phosphatase, Non-Receptor Type 11 - A subtype of non-receptor protein tyrosine phosphatases that contain two SRC HOMOLOGY DOMAINS. Mutat...

Protein Tyrosine Phosphatase, Non-Receptor Type 12 - A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N...

Protein Tyrosine Phosphatase, Non-Receptor Type 13 - A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an ...

Protein Tyrosine Phosphatase, Non-Receptor Type 2 - A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE P...

Protein Tyrosine Phosphatase, Non-Receptor Type 22 - A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an ...

Protein Tyrosine Phosphatase, Non-Receptor Type 3 - A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an ...

Protein Tyrosine Phosphatase, Non-Receptor Type 4 - A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an ...

Protein Tyrosine Phosphatase, Non-Receptor Type 6 - A Src-homology domain-containing protein tyrosine phosphatase found in the CYTOSOL of hematopoietic ...

Protein Tyrosine Phosphatases, Non-Receptor - A subcategory of protein tyrosine phosphatases that occur in the CYTOPLASM. Many of the proteins in ...

Proteinase Inhibitory Proteins, Secretory - Peptides and proteins found in BODILY SECRETIONS and BODY FLUIDS that are PROTEASE INHIBITORS. They ...

Proteins - Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, clea...

Proteochondroitin Sulfates - Proteoglycans found in cartilage. They consist of several chondroitin sulfate molecules linked to pr...

Proteoglycans - Glycoproteins which have a very high polysaccharide content....

Proteolipids - Protein-lipid combinations abundant in brain tissue, but also present in a wide variety of animal an...

Proteome - The protein complement of an organism coded for by its genome....

Prothrombin - A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothr...

Proton Pumps - Integral membrane proteins that transport protons across a membrane. This transport can be linked to...

Proton-Phosphate Symporters - Proteins that cotransport hydrogen ions and phosphate ions across cellular membranes....

Proton-Translocating ATPases - Multisubunit enzymes that reversibly synthesize ADENOSINE TRIPHOSPHATE. They are coupled to the tran...

Proto-Oncogene Protein c-ets-1 - An ets proto-oncogene expressed primarily in adult LYMPHOID TISSUE; BRAIN; and VASCULAR ENDOTHELIAL ...

Proto-Oncogene Protein c-ets-2 - A ubiquitously expressed ets proto-oncogene protein that may play a role in regulation of CELL PROLI...

Proto-Oncogene Protein c-fli-1 - A member of the c-ets family of transcription factors that is preferentially expressed in cells of h...

Proto-Oncogene Proteins - Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are...

Proto-Oncogene Proteins A-raf - A raf kinase subclass expressed primarily in non-neuronal tissues such as SKELETAL MUSCLE. The A-raf...

Proto-Oncogene Proteins B-raf - A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kina...

Proto-Oncogene Proteins c-abl - Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm...

Proto-Oncogene Proteins c-akt - A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS...

Proto-Oncogene Proteins c-bcl-2 - Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPT...

Proto-Oncogene Proteins c-bcl-6 - A DNA-binding protein that represses GENETIC TRANSCRIPTION of target genes by recruiting HISTONE DEA...

Proto-Oncogene Proteins c-bcr - Proto-oncogene protein bcr is a serine-threonine kinase that functions as a negative regulator of CE...

Proto-Oncogene Proteins c-cbl - Proto-oncogene proteins that negatively regulate RECEPTOR PROTEIN-TYROSINE KINASE signaling. It is a...

Proto-Oncogene Proteins c-crk - Signal transducing adaptor proteins that contain SRC HOMOLOGY DOMAINS and play a role in CYTOSKELETO...

Proto-Oncogene Proteins c-ets - A family of transcription factors that share a unique DNA-binding domain. The name derives from vira...

Proto-Oncogene Proteins c-fes - Proto-oncogene proteins fes are protein-tyrosine kinases with a central SH2 DOMAIN. It has been impl...

Proto-Oncogene Proteins c-fos - Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-r...

Proto-Oncogene Proteins c-fyn - Src-family kinases that associate with T-CELL ANTIGEN RECEPTOR and phosphorylate a wide variety of i...

Proto-Oncogene Proteins c-hck - Members of the src-family tyrosine kinase family that are strongly expressed in MYELOID CELLS and B-...

Proto-Oncogene Proteins c-jun - Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-r...

Proto-Oncogene Proteins c-kit - A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucia...

Proto-Oncogene Proteins c-maf - Maf proto-oncogene protein is the major cellular homolog of the V-MAF ONCOGENE PROTEIN. It was the f...

Proto-Oncogene Proteins c-mdm2 - An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to...

Proto-Oncogene Proteins c-met - Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extr...

Proto-Oncogene Proteins c-mos - Cellular proteins encoded by the c-mos genes (GENES, MOS). They function in the cell cycle to mainta...

Proto-Oncogene Proteins c-myb - Cellular DNA-binding proteins encoded by the myb gene (GENES, MYB). They are expressed in a wide var...

Proto-Oncogene Proteins c-myc - Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid...

Proto-Oncogene Proteins c-pim-1 - Serine-threonine protein kinases that relay signals from CYTOKINE RECEPTORS and are involved in cont...

Proto-Oncogene Proteins c-raf - A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. T...

Proto-Oncogene Proteins c-rel - Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately...

Proto-Oncogene Proteins c-ret - Receptor protein-tyrosine kinases involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC ...

Proto-Oncogene Proteins c-sis - Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B cha...

Proto-Oncogene Proteins c-vav - Proto-oncogene proteins that are guanine nucleotide exchange factors for RHO GTPASES. They also func...

Proto-Oncogene Proteins c-yes - Members of the src-family tyrosine kinases that are activated during the transition from G2 PHASE to...

Proto-Oncogene Proteins p21(ras) - Cellular proteins encoded by the H-ras, K-ras and N-ras genes. The proteins have GTPase activity and...

Proto-Oncogene Proteins pp60(c-src) - Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important rol...

Protoporphyrinogen Oxidase - A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen...

Protozoan Proteins - Proteins found in any species of protozoan....

PrP 27-30 Protein - Protease-resistant core of PrPSC, the abnormal isoform of prion proteins (PRIONS). PrP 27-30 is prod...

PrPC Proteins - Normal cellular isoform of prion proteins (PRIONS) encoded by a chromosomal gene and found in normal...

PrPSc Proteins - Abnormal isoform of prion proteins (PRIONS) resulting from a posttranslational modification of the c...

P-Selectin - Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to act...

PTEN Phosphohydrolase - A lipid phosphatase that acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL...

Pulmonary Surfactant-Associated Protein A - An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resul...

Pulmonary Surfactant-Associated Protein B - A pulmonary surfactant associated-protein that plays an essential role in alveolar stability by lowe...

Pulmonary Surfactant-Associated Protein C - A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the su...

Pulmonary Surfactant-Associated Protein D - An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens and en...

Pulmonary Surfactant-Associated Proteins - Proteins found in the LUNG that act as PULMONARY SURFACTANTS....

Pyocins - Bacteriocins elaborated by mutant strains of Pseudomonas aeruginosa. They are protein or protein-lip...

Pyroglobulins - Atypical gamma immunoglobulins characterized by their irreversible heat denaturation at 56-degrees C...

Qa-SNARE Proteins - A subfamily of Q-SNARE PROTEINS which occupy the same position as syntaxin 1A in the SNARE complex a...

Qb-SNARE Proteins - A subfamily of Q-SNARE PROTEINS which occupy the same position in the SNARE complex as the N-termina...

Qc-SNARE Proteins - A subfamily of Q-SNARE PROTEINS which occupy the same position in the SNARE complex as the C-termina...

Q-SNARE Proteins - SNARE proteins in which the central amino acid residue of the SNARE motif is a GLUTAMINE. They are c...

rab GTP-Binding Proteins - A large family of MONOMERIC GTP-BINDING PROTEINS that play a key role in cellular secretory and endo...

rab1 GTP-Binding Proteins - A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in vesicle transport between th...

rab2 GTP-Binding Protein - A protein involved in transport between the ENDOPLASMIC RETICULUM and the GOLGI APPARATUS. This enzy...

rab3 GTP-Binding Proteins - A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in calcium-dependent EXOCYTOSIS...

rab3A GTP-Binding Protein - The most abundant member of the RAB3 GTP-BINDING PROTEINS. It is involved in calcium-dependent EXOCY...

rab4 GTP-Binding Proteins - A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in recycling of proteins such a...

rab5 GTP-Binding Proteins - A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in transport from the cell memb...

rac GTP-Binding Proteins - A sub-family of RHO GTP-BINDING PROTEINS that is involved in regulating the organization of cytoskel...

rac1 GTP-Binding Protein - A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls...

Rad51 Recombinase - A Rec A recombinase found in eukaryotes. Rad51 is involved in DNA REPAIR of double-strand breaks....

Rad52 DNA Repair and Recombination Protein - A DNA-binding protein that mediates DNA REPAIR of double strand break, and GENETIC RECOMBINATION....

raf Kinases - A family of closely-related serine-threonine kinases that were originally identified as the cellular...

ral GTP-Binding Proteins - A family of ubiquitously expressed MONOMERIC GTP-BINDING PROTEINS that are involved in intracellular...

ral Guanine Nucleotide Exchange Factor - A guanine nucleotide exchange factor that stimulates the dissociation of GDP from RAL GTP-BINDING PR...

ran GTP-Binding Protein - A monomeric GTP-binding protein involved in nucleocytoplasmic transport of proteins into the nucleus...

RANK Ligand - A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds R...

rap GTP-Binding Proteins - A family of MONOMERIC GTP-BINDING PROTEINS that are related to RAS PROTEINS.This enzyme was formerly...

rap1 GTP-Binding Proteins - A genetically related subfamily of RAP GTP-BINDING PROTEINS that share homology with RAS PROTEINS. T...

ras GTPase-Activating Proteins - PROTEINS that specifically activate the GTP-phosphohydrolase activity of RAS PROTEINS....

ras Guanine Nucleotide Exchange Factors - A family of GUANINE NUCLEOTIDE EXCHANGE FACTORS that are specific for RAS PROTEINS....

ras Proteins - Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived p...

ras-GRF1 - A guanine nucleotide exchange factor that is expressed primarily in neuronal tissue and may be speci...

Reagins - Antibodies, especially IGE, that bind to tissue of the same species so that ANTIGENS induce release ...

Receptor Activator of Nuclear Factor-kappa B - A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in ...

Receptor Protein-Tyrosine Kinases - A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity....

Receptor Tyrosine Kinase-like Orphan Receptors - A family of cell surface receptors that were originally identified by their structural homology to n...

Receptor, Adenosine A1 - A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of tissues including the BRAIN ...

Receptor, Adenosine A2A - A subclass of adenosine A2 receptors found in LEUKOCYTES, the SPLEEN, the THYMUS and a variety of ot...

Receptor, Adenosine A2B - A subclass of adenosine A2 receptors found in the CECUM, the COLON, the BLADDER, and a variety of ot...

Receptor, Adenosine A3 - A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of locations including the BRAI...

Receptor, Anaphylatoxin C5a - A G-protein-coupled receptor that signals an increase in intracellular calcium in response to the po...

Receptor, Angiotensin, Type 1 - An angiotensin receptor subtype that is expressed at high levels in a variety of adult tissues inclu...

Receptor, Angiotensin, Type 2 - An angiotensin receptor subtype that is expressed at high levels in fetal tissues. Many effects of t...

Receptor, Bradykinin B1 - A subtype of bradykinin receptor that is induced in response to INFLAMMATION. It may play a role in ...

Receptor, Bradykinin B2 - A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of...

Receptor, Cannabinoid, CB1 - A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may pl...

Receptor, Cannabinoid, CB2 - A subclass of cannabinoid receptor found primarily on immune cells where it may play a role modulati...

Receptor, Cholecystokinin A - A subtype of cholecystokinin receptor found primarily in the PANCREAS; STOMACH; INTESTINE; and GALLB...

Receptor, Cholecystokinin B - A subtype of cholecystokinin receptor found primarily in the CENTRAL NERVOUS SYSTEM and the GASTRIC ...

Receptor, Ciliary Neurotrophic Factor - Cell surface receptors for CILIARY NEUROTROPHIC FACTOR. They are heterotrimeric proteins formed by t...

Receptor, Endothelin A - A subtype of endothelin receptor found predominantly in the VASCULAR SMOOTH MUSCLE. It has a high af...

Receptor, Endothelin B - A subtype of endothelin receptor found predominantly in the KIDNEY. It may play a role in reducing s...

Receptor, EphA1 - The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producin...

Receptor, EphA2 - An Eph family receptor found abundantly in tissues of epithelial origin. It is expressed in a divers...

Receptor, EphA3 - An eph family receptor that is found primarily in adult BRAIN and variety of tissues in the developi...

Receptor, EphA4 - An eph family receptor found in variety of tissues including BRAIN. During embryogenesis, EphA4 rece...

Receptor, EphA5 - An eph family receptor found primarily in differentiated neuronal tissues. Several isoforms of EphA5...

Receptor, EphA6 - An eph family receptor that is found in a variety of neuronal regions of the BRAIN. In contrast to t...

Receptor, EphA7 - An eph family receptor found widely expressed in embryo tissues, including the NERVOUS SYSTEM. In th...

Receptor, EphA8 - An eph family receptor found exclusively in BRAIN. EphA8 receptors may play a role in the axonal gui...

Receptor, EphB1 - An eph family receptor found primarily in the nervous system. In the embryonic BRAIN EphB1 receptor ...

Receptor, EphB2 - An eph family receptor found widely expressed in embryonic and adult tissues. High levels of EphB2 r...

Receptor, EphB3 - An eph family receptor found in a number of tissues including BRAIN; LUNG; KIDNEY; PANCREAS; INTESTI...

Receptor, EphB4 - An eph family receptor found in a variety of adult and embryonic tissues. Unlike the majority of pro...

Receptor, EphB5 - An eph family receptor found at high levels in adult THYMUS and RETINA. In embryonic tissues it is f...

Receptor, EphB6 - An eph family receptor found primarily in BRAIN and THYMUS. The EphB6 receptor is unusual in that it...

Receptor, Epidermal Growth Factor - A cell surface receptor involved in regulation of cell growth and differentiation. It is specific fo...

Receptor, erbB-2 - A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant n...

Receptor, erbB-3 - A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive h...

Receptor, Fibroblast Growth Factor, Type 1 - A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE ...

Receptor, Fibroblast Growth Factor, Type 2 - A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in ...

Receptor, Fibroblast Growth Factor, Type 3 - A fibroblast growth factor receptor that regulates CHONDROCYTE growth and CELL DIFFERENTIATION. Muta...

Receptor, Fibroblast Growth Factor, Type 4 - A fibroblast growth factor receptor that is mainly expressed in LUNG; KIDNEY; PANCREAS; and SPLEEN. ...

Receptor, Fibroblast Growth Factor, Type 5 - The most divergent of the known fibroblast growth factor receptors. It does not contain an intracell...

Receptor, Galanin, Type 1 - The most abundant galanin receptor subtype. It displays a high affinity for the full-length form of ...

Receptor, Galanin, Type 2 - A galanin receptor subtype with broad specificity for full length GALANIN, galanin peptide fragments...

Receptor, Galanin, Type 3 - A galanin receptor subtype with high affinity for GALANIN-LIKE PEPTIDE and low affinity for full len...

Receptor, IGF Type 1 - A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Alt...

Receptor, IGF Type 2 - A receptor that is specific for IGF-II and mannose-6-phosphate. The receptor is a 250-kDa single cha...

Receptor, Insulin - A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits whic...

Receptor, Interferon alpha-beta - A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTER...

Receptor, Macrophage Colony-Stimulating Factor - A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS)...

Receptor, Melanocortin, Type 1 - A melanocortin receptor subtype found primarily in MELANOCYTES. It shows specificity for ALPHA-MSH a...

Receptor, Melanocortin, Type 2 - A melanocortin receptor subtype found primarily in the ADRENAL CORTEX. It shows specificity for ADRE...

Receptor, Melanocortin, Type 3 - A melanocortin receptor subtype found primarily in BRAIN. It shows specificity for ALPHA-MSH; BETA-M...

Receptor, Melanocortin, Type 4 - A melanocortin receptor subtype found primarily in BRAIN. It shows specificity for ALPHA-MSH; BETA-M...

Receptor, Melatonin, MT1 - A melatonin receptor subtype that is primarily found in the HYPOTHALAMUS and in the KIDNEY....

Receptor, Melatonin, MT2 - A melatonin receptor subtype primarily found expressed in the BRAIN and RETINA....

Receptor, Muscarinic M1 - A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is f...

Receptor, Muscarinic M2 - A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-c...

Receptor, Muscarinic M3 - A subclass of muscarinic receptor that mediates cholinergic-induced contraction in a variety of SMOO...

Receptor, Muscarinic M4 - A specific subtype of muscarinic receptor found in the CORPUS STRIATUM and the LUNG. It has similar ...

Receptor, Muscarinic M5 - A specific subtype of muscarinic receptor found in a variety of locations including the SALIVARY GLA...

Receptor, Nerve Growth Factor - A low affinity receptor that binds NERVE GROWTH FACTOR; BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROP...

Receptor, Notch1 - A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS...

Receptor, Notch2 - A notch receptor that plays an important role in CELL DIFFERENTIATION in a variety of cell types. It...

Receptor, PAR-1 - A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the act...

Receptor, PAR-2 - A G-protein-coupled, proteinase-activated receptor that is expressed in a variety of tissues includi...

Receptor, Parathyroid Hormone, Type 1 - A parathyroid hormone receptor subtype that recognizes both PARATHYROID HORMONE and PARATHYROID HORM...

Receptor, Parathyroid Hormone, Type 2 - A parathyroid hormone receptor subtype found in the BRAIN and the PANCREAS. It is a G-protein-couple...

Receptor, Platelet-Derived Growth Factor alpha - A PDGF receptor that binds specifically to both PDGF-A chains and PDGF-B chains. It contains a prote...

Receptor, Platelet-Derived Growth Factor beta - A PDGF receptor that binds specifically to the PDGF-B chain. It contains a protein-tyrosine kinase a...

Receptor, Serotonin, 5-HT1A - A serotonin receptor subtype found distributed through the CENTRAL NERVOUS SYSTEM where they are inv...

Receptor, Serotonin, 5-HT1B - A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It pl...

Receptor, Serotonin, 5-HT1D - A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBEN...

Receptor, Serotonin, 5-HT2A - A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the co...

Receptor, Serotonin, 5-HT2B - A serotonin receptor subtype found in the BRAIN; HEART; LUNGS; PLACENTA and DIGESTIVE SYSTEM organs....

Receptor, Serotonin, 5-HT2C - A serotonin receptor subtype found primarily in the CENTRAL NERVOUS SYSTEM and the CHOROID PLEXUS. T...

Receptor, TIE-1 - A TIE receptor found predominantly on ENDOTHELIAL CELLS. It is considered essential for vascular dev...

Receptor, TIE-2 - A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required...

Receptor, trkA - A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotr...

Receptor, trkB - A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROP...

Receptor, trkC - A protein-tyrosine kinase receptor that is specific for NEUROTROPHIN 3. It is widely expressed in ne...

Receptor-CD3 Complex, Antigen, T-Cell - Molecule composed of the non-covalent association of the T-cell antigen receptor (RECEPTORS, ANTIGEN...

Receptor-Interacting Protein Serine-Threonine Kinase 2 - A RIP serine-theonine kinase that contains a C-terminal caspase activation and recruitment domain. I...

Receptor-Interacting Protein Serine-Threonine Kinases - A family of serine-threonine kinases that plays a role in intracellular signal transduction by inter...

Receptor-Like Protein Tyrosine Phosphatases - A subcategory of protein tyrosine phosphatases that are bound to the cell membrane. They contain cyt...

Receptor-Like Protein Tyrosine Phosphatases, Class 1 - A subclass of receptor-like protein tryosine phosphatases that contain heavily glycosylated and cyst...

Receptor-Like Protein Tyrosine Phosphatases, Class 2 - A subclass of receptor-like protein tryosine phosphatases that contain multiple extracellular immuno...

Receptor-Like Protein Tyrosine Phosphatases, Class 3 - A subclass of receptor-like protein tryosine phosphatases that contain a single cytosolic protein ty...

Receptor-Like Protein Tyrosine Phosphatases, Class 4 - A subclass of receptor-like protein tryosine phosphatases that contain short highly glycosylated ext...

Receptor-Like Protein Tyrosine Phosphatases, Class 5 - A subclass of receptor-like protein tryosine phosphatases that contain an extracellular fibronectin ...

Receptor-Like Protein Tyrosine Phosphatases, Class 7 - A subclass of receptor-like protein tryosine phosphatases that contain a short extracellular domain,...

Receptor-Like Protein Tyrosine Phosphatases, Class 8 - A subclass of receptor-like protein tryosine phosphatases that contain an extracellular RDGS-adhesio...

Receptors, Adenosine A2 - A subclass of ADENOSINE RECEPTORS that are generally considered to be coupled to the GS, STIMULATORY...

Receptors, Adipokine - Cell surface receptors for ADIPOKINES, cytokines secreted by the ADIPOCYTES....

Receptors, Adiponectin - Cell surface receptors for ADIPONECTIN, an antidiabetic hormone secreted by ADIPOCYTES. Adiponectin ...

Receptors, Adrenergic - Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger int...

Receptors, Adrenergic, alpha - One of the two major pharmacological subdivisions of adrenergic receptors. The alpha-beta distinctio...

Receptors, Adrenergic, alpha-1 - A subclass of alpha-adrenergic receptors (RECEPTORS, ADRENERGIC, ALPHA). alpha-1 Adrenergic receptor...

Receptors, Adrenergic, alpha-2 - A subclass of alpha-adrenergic receptors (RECEPTORS, ADRENERGIC, ALPHA). alpha-2 Adrenergic receptor...

Receptors, Adrenergic, beta - One of the two major pharmacologically defined classes of adrenergic receptors. The alpha-beta disti...

Receptors, Adrenergic, beta-1 - A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). beta-1 Adrenergic receptors a...

Receptors, Adrenergic, beta-2 - A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). beta-2 Adrenergic receptors a...

Receptors, Adrenergic, beta-3 - A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). beta-3 Adrenergic receptors a...

Receptors, Albumin - Cell surface proteins that bind albumin with high affinity and trigger intracellular changes influen...

Receptors, Aldosterone - Cytoplasmic proteins that specifically bind aldosterone and mediate its cellular effects. The aldost...

Receptors, Amino Acid - Cell surface proteins that bind amino acids and trigger changes which influence the behavior of cell...

Receptors, AMPA - Cell surface proteins that bind glutamate and directly gate ion channels in cell membranes. AMPA rec...

Receptors, Androgen - Proteins, generally found in the CYTOPLASM, that specifically bind ANDROGENS and mediate their cellu...

Receptors, Angiotensin - Cell surface proteins that bind ANGIOTENSINS and trigger intracellular changes influencing the behav...

Receptors, Antigen - Molecules on the surface of B- and T-lymphocytes that recognize and combine with specific antigens....

Receptors, Antigen, B-Cell - IMMUNOGLOBULINS on the surface of B-LYMPHOCYTES. Their MESSENGER RNA contains an EXON with a membran...

Receptors, Antigen, T-Cell - Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors ar...

Receptors, Antigen, T-Cell, alpha-beta - T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primaril...

Receptors, Antigen, T-Cell, gamma-delta - T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primari...

Receptors, Aryl Hydrocarbon - Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate t...

Receptors, Atrial Natriuretic Factor - Cell surface proteins that bind ATRIAL NATRIURETIC FACTOR with high affinity and trigger intracellul...

Receptors, Biogenic Amine - Cell surface proteins that bind biogenic amines with high affinity and regulate intracellular signal...

Receptors, Bombesin - Cell surface proteins that bind bombesin or closely related peptides with high affinity and trigger ...

Receptors, Bradykinin - Cell surface receptors that bind BRADYKININ and related KININS with high affinity and trigger intrac...

Receptors, Calcitonin - Cell surface proteins that bind calcitonin and trigger intracellular changes which influence the beh...

Receptors, Calcitonin Gene-Related Peptide - Cell surface proteins that bind calcitonin gene-related peptide (CGRP) with high affinity and trigge...

Receptors, Calcitriol - Proteins, usually found in the cytoplasm, that specifically bind calcitriol, migrate to the nucleus,...

Receptors, Calcium-Sensing - A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-s...

Receptors, Cannabinoid - A class of G-protein-coupled receptors that are specific for CANNABINOIDS such as those derived from...

Receptors, Catecholamine - Cell surface proteins that bind catecholamines with high affinity and trigger intracellular changes ...

Receptors, CCR - Chemokine receptors that are specific for CC CHEMOKINES....

Receptors, CCR1 - CCR receptors with specificity for a broad variety of CC CHEMOKINES. They are expressed at high leve...

Receptors, CCR10 - CCR receptors with specificity for CHEMOKINE CCL27. They may play a specialized role in the cutaneou...

Receptors, CCR2 - CCR receptors with specificity for CHEMOKINE CCL2 and several other CCL2-related chemokines. They ar...

Receptors, CCR3 - CCR receptors with specificity for CHEMOKINE CCL11 and a variety of other CC CHEMOKINES. They are ex...

Receptors, CCR4 - CCR receptors with specificity for CHEMOKINE CCL17 and CHEMOKINE CCL22. They are expressed at high l...

Receptors, CCR5 - CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expr...

Receptors, CCR6 - CCR receptors with specificity for CHEMOKINE CCL20. They are expressed at high levels in T-LYMPHOCYT...

Receptors, CCR7 - CCR receptors with specificity for CHEMOKINE CCL19 and CHEMOKINE CCL21. They are expressed at high l...

Receptors, CCR8 - CCR receptors with specificity for CHEMOKINE CCL1. They are expressed at high levels in T-LYMPHOCYTE...

Receptors, Cell Surface - Cell surface proteins that bind signalling molecules external to the cell with high affinity and con...

Receptors, Chemokine - Cell surface glycoproteins that bind to chemokines and thus mediate the migration of pro-inflammator...

Receptors, Cholecystokinin - Cell surface proteins that bind cholecystokinin (CCK) with high affinity and trigger intracellular c...

Receptors, Cholinergic - Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes i...

Receptors, Collagen - Collagen receptors are cell surface receptors that modulate signal transduction between cells and th...

Receptors, Colony-Stimulating Factor - Cell surface receptors for colony stimulating factors, local mediators, and hormones that regulate t...

Receptors, Complement - Molecules on the surface of some B-lymphocytes and macrophages, that recognize and combine with the ...

Receptors, Complement 3b - Molecular sites on or in some B-lymphocytes and macrophages that recognize and combine with COMPLEME...

Receptors, Complement 3d - Molecular sites on or in B-lymphocytes, follicular dendritic cells, lymphoid cells, and epithelial c...

Receptors, Concanavalin A - Glycoprotein moieties on the surfaces of cell membranes that bind concanavalin A selectively; the nu...

Receptors, Corticotropin - Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affini...

Receptors, Corticotropin-Releasing Hormone - Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intra...

Receptors, CXCR - Chemokine receptors that are specific for CXC CHEMOKINES....

Receptors, CXCR3 - CXCR receptors that are expressed on the surface of a number of cell types, including T-LYMPHOCYTES;...

Receptors, CXCR4 - CXCR receptors with specificity for CXCL12 CHEMOKINE. The receptors may play a role in HEMATOPOIESIS...

Receptors, CXCR5 - CXCR receptors isolated initially from BURKITT LYMPHOMA cells. CXCR5 receptors are expressed on matu...

Receptors, Cyclic AMP - Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes whic...

Receptors, Cytoadhesin - A group of INTEGRINS that includes the platelet outer membrane glycoprotein GPIIb-IIIa (PLATELET GLY...

Receptors, Cytokine - Cell surface proteins that bind cytokines and trigger intracellular changes influencing the behavior...

Receptors, Cytoplasmic and Nuclear - Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracell...

Receptors, Death Domain - A family of cell surface receptors that signal via a conserved domain that extends into the cell CYT...

Receptors, Dopamine - Cell-surface proteins that bind dopamine with high affinity and trigger intracellular changes influe...

Receptors, Dopamine D1 - A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its ...

Receptors, Dopamine D2 - A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its ...

Receptors, Dopamine D3 - A subtype of dopamine D2 receptors that are highly expressed in the LIMBIC SYSTEM of the brain....

Receptors, Dopamine D4 - A subtype of dopamine D2 receptors that has high affinity for the antipsychotic CLOZAPINE....

Receptors, Dopamine D5 - A subtype of dopamine D1 receptors that has higher affinity for DOPAMINE and differentially couples ...

Receptors, Drug - Proteins that bind specific drugs with high affinity and trigger intracellular changes influencing t...

Receptors, Ectodysplasin - Members of the TNF receptor family that are specific for ECTODYSPLASIN. At least two subtypes of the...

Receptors, Eicosanoid - Cell surface proteins that bind eicosanoids with high affinity and trigger intracellular changes inf...

Receptors, Endothelin - Cell surface proteins that bind ENDOTHELINS with high affinity and trigger intracellular changes whi...

Receptors, Eph Family - A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this ...

Receptors, Epoprostenol - Cell surface receptors for EPOPROSTENOL. They are coupled to HETEROTRIMERIC G-PROTEINS....

Receptors, Erythropoietin - Cell surface proteins that bind erythropoietin with high affinity and trigger intracellular changes ...

Receptors, Estradiol - Cytoplasmic proteins that bind estradiol, migrate to the nucleus, and regulate DNA transcription....

Receptors, Estrogen - Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcri...

Receptors, Fc - Molecules found on the surface of some, but not all, B-lymphocytes, T-lymphocytes, and macrophages, ...

Receptors, Fibrinogen - Receptors that bind FIBRINOGEN through distinct adhesive sequences on the fibrinogen molecule. Altho...

Receptors, Fibroblast Growth Factor - Specific molecular sites or structures on cell membranes that react with FIBROBLAST GROWTH FACTORS (...

Receptors, Fibronectin - Specific cell surface receptors which bind to FIBRONECTINS. Studies have shown that these receptors ...

Receptors, Formyl Peptide - A family of G-protein-coupled receptors that was originally identified by its ability to bind N-form...

Receptors, FSH - Cell surface proteins that bind FOLLICLE STIMULATING HORMONE with high affinity and trigger intracel...

Receptors, GABA - Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that ...

Receptors, GABA-A - Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and control an integral membrane chloride c...

Receptors, GABA-B - Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G...

Receptors, Galanin - A family of G-protein-coupled receptors that are specific for GALANIN and galanin peptides. They are...

Receptors, Gastrointestinal Hormone - Cell surface proteins that bind gastrointestinal hormones with high affinity and trigger intracellul...

Receptors, Ghrelin - Transmembrane proteins that recognize and bind GHRELIN, a potent stimulator of GROWTH HORMONE secret...

Receptors, Glucagon - Cell surface receptors that bind glucagon with high affinity and trigger intracellular changes which...

Receptors, Glucocorticoid - Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The ...

Receptors, Glutamate - Cell-surface proteins that bind glutamate and trigger changes which influence the behavior of cells....

Receptors, Glycine - Cell surface receptors that bind glycine with high affinity and trigger intracellular changes which ...

Receptors, Gonadotropin - Those protein complexes or molecular sites on the surfaces of gonadal and other sensitive cells that...

Receptors, G-Protein-Coupled - The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common st...

Receptors, Granulocyte Colony-Stimulating Factor - Receptors that bind and internalize GRANULOCYTE COLONY-STIMULATING FACTOR. Their MW is believed to b...

Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - Receptors that bind and internalize the granulocyte-macrophage stimulating factor. Their MW is belie...

Receptors, Growth Factor - Cell surface receptors that bind growth or trophic factors with high affinity, triggering intracellu...

Receptors, Guanylate Cyclase-Coupled - A class of cellular membrane receptors that either have an intrinsic guanylate cyclase activity or a...

Receptors, Histamine - Cell-surface proteins that bind histamine and trigger intracellular changes influencing the behavior...

Receptors, Histamine H1 - A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamin...

Receptors, Histamine H2 - A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 ...

Receptors, Histamine H3 - A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H3 ...

Receptors, HIV - Cellular receptors that bind the human immunodeficiency virus that causes AIDS. Included are CD4 ANT...

Receptors, IgE - Specific molecular sites on the surface of B- and T-lymphocytes which combine with IgEs. Two subclas...

Receptors, IgG - Specific molecular sites on the surface of various cells, including B-lymphocytes and macrophages, t...

Receptors, Immunologic - Cell surface molecules on cells of the immune system that specifically bind surface molecules or mes...

Receptors, Interferon - Specific molecular sites or structures on or in cells with which interferons react or to which they ...

Receptors, Interleukin - Cell surface proteins that bind interleukins and trigger intracellular changes influencing the behav...

Receptors, Interleukin-1 - Cell surface receptors that are specific for INTERLEUKIN-1. Included under this heading are signalin...

Receptors, Interleukin-1 Type I - An interleukin-1 receptor subtype that is involved in signaling cellular responses to INTERLEUKIN-1A...

Receptors, Interleukin-1 Type II - An interleukin-1 receptor subtype that competes with the INTERLEUKIN-1 RECEPTOR TYPE I for binding t...

Receptors, Interleukin-10 - Cell surface receptors for INTERLEUKIN-10. They exist as a tetramer of two alpha chains (INTERLEUKIN...

Receptors, Interleukin-11 - Cell surface receptors that are specific for INTERLEUKIN-11. They consist of heterodimers of the INT...

Receptors, Interleukin-12 - Cell surface receptors for INTERLEUKIN-12. They exist as dimers of beta 1 and beta 2 subunits. Signa...

Receptors, Interleukin-13 - Cell surface receptors for INTERLEUKIN-13. Included under this heading are the INTERLEUKIN-13 RECEPT...

Receptors, Interleukin-15 - Cell surface receptors for INTERLEUKIN-15. They are widely-distributed heterotrimeric proteins consi...

Receptors, Interleukin-16 - Cell surface receptors for INTERLEUKIN-16. Although initial studies have identified CD4 ANTIGENS as ...

Receptors, Interleukin-17 - Cell surface receptors for INTERLEUKIN-17. Several subtypes of receptors have been found, each with ...

Receptors, Interleukin-18 - Cell surface receptors for INTERLEUKIN-18 found on a variety of cell types including MACROPHAGES; NE...

Receptors, Interleukin-2 - Receptors present on activated T-LYMPHOCYTES and B-LYMPHOCYTES that are specific for INTERLEUKIN-2 a...

Receptors, Interleukin-21 - Cell surface receptors for interleukin 21. They are heterodimeric proteins found on DENDRITIC CELLS ...

Receptors, Interleukin-3 - High affinity receptors for INTERLEUKIN-3. They are found on early HEMATOPOIETIC PROGENITOR CELLS; p...

Receptors, Interleukin-4 - Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are speci...

Receptors, Interleukin-4, Type I - An interleukin-4 receptor subtype that is found predominantly on hematopoietic cells. It is a hetero...

Receptors, Interleukin-4, Type II - An interleukin receptor subtype found on both hematopoietic and non-hematopoietic cells. It is a mem...

Receptors, Interleukin-5 - Cell surface receptors that are specific for INTERLEUKIN-5. They are heterodimeric proteins consisti...

Receptors, Interleukin-6 - Cell surface receptors that are specific for INTERLEUKIN-6. They are present on T-LYMPHOCYTES, mitog...

Receptors, Interleukin-7 - Cell surface receptors that are specific for INTERLEUKIN-7. They are present on T-LYMPHOCYTES and B-...

Receptors, Interleukin-8 - Cell surface receptors that are specific for INTERLEUKIN-8. Two specific receptor subtypes (type A a...

Receptors, Interleukin-8A - High-affinity G-protein-coupled receptors for INTERLEUKIN-8 present on NEUTROPHILS; MONOCYTES; and B...

Receptors, Interleukin-8B - High-affinity G-protein-coupled receptors for INTERLEUKIN-8 present on NEUTROPHILS; MONOCYTES; and T...

Receptors, Interleukin-9 - A cell surface receptor that specifically mediates the biological effects of INTERLEUKIN-9. The func...

Receptors, Invertebrate Peptide - Cell surface receptors for invertebrate peptide hormones or neuropeptides....

Receptors, Kainic Acid - Cell surface proteins that bind glutamate and directly gate ion channels. Kainic acid receptors were...

Receptors, KIR - A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR rec...

Receptors, KIR2DL1 - A KIR receptor that has specificity for HLA-C ANTIGENS. It is an inhibitory receptor that contains D...

Receptors, KIR2DL2 - A KIR receptor that has specificity for HLA-C ANTIGENS. It is an inhibitory receptor that contains D...

Receptors, KIR2DL3 - A KIR receptor that has specificity for HLA-C ANTIGEN. It is an inhibitory receptor that contains D1...

Receptors, KIR2DL4 - A KIR receptor that has specificity for HLA-G antigen. It contains D0 and D2 extracellular immunoglo...

Receptors, KIR2DL5 - An inhibitory KIR receptor that contains D0 and D1 extracellular immunoglobulin-like domains and a l...

Receptors, KIR3DL1 - A KIR receptor that has specificity for HLA-B ANTIGENS. It is an inhibitory receptor that contains D...

Receptors, KIR3DL2 - A KIR receptor that has specificity for HLA-A3 ANTIGEN. It is an inhibitory receptor that contains D...

Receptors, KIR3DS1 - An activating KIR receptor that contains D0, D1, and D2 extracellular immunoglobulin-like domains an...

Receptors, Laminin - Glycoprotein molecules on the surface of cells that react with or bind to laminin whose function all...

Receptors, LDL - Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are l...

Receptors, Leptin - Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon...

Receptors, Leukocyte-Adhesion - Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain...

Receptors, Leukotriene - Cell-surface receptors that bind LEUKOTRIENES with high affinity and trigger intracellular changes i...

Receptors, Leukotriene B4 - A class of cell surface leukotriene receptors with a preference for leukotriene B4. Leukotriene B4 r...

Receptors, LH - Those protein complexes or molecular sites on the surfaces and cytoplasm of gonadal cells that bind ...

Receptors, LHRH - Receptors with a 6-kDa protein on the surfaces of cells that secrete LUTEINIZING HORMONE or FOLLICLE...

Receptors, Lipoprotein - Cell surface proteins that bind lipoproteins with high affinity. Lipoprotein receptors in the liver ...

Receptors, Lipoxin - Cell surface proteins that bind LIPOXINS with high affinity and trigger intracellular changes influe...

Receptors, Lymphocyte Homing - Cell surface glycoproteins on lymphocytes and other leukocytes that mediate adhesion to specialized ...

Receptors, Lysophosphatidic Acid - A subfamily of lysophospholipid receptors with specificity for LYSOPHOSPHATIDIC ACIDS....

Receptors, Lysophospholipid - A family of G-protein-coupled receptors that bind to specific LYSOPHOSPHOLIPIDS such as lysophosphat...

Receptors, Lysosphingolipid - A subfamily of lysophospholipid receptors with specificity for LYSOSPHINGOLIPIDS such as sphingosine...

Receptors, Mating Factor - A family of pheromone receptors that were initially discovered in SACCHAROMYCES CEREVISIAE as protei...

Receptors, Melanocortin - A family of G-protein-coupled receptors that have specificity for MELANOCYTE-STIMULATING HORMONES an...

Receptors, Melatonin - A family of G-protein-coupled receptors that are specific for and mediate the effects of MELATONIN. ...

Receptors, Metabotropic Glutamate - Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger s...

Receptors, Mineralocorticoid - Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. T...

Receptors, Mitogen - Glycoprotein molecules on the surface of B- and T-lymphocytes, that react with molecules of antilymp...

Receptors, Muscarinic - One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined ...

Receptors, N-Acetylglucosamine - Cell surface receptors that bind to ACETYLGLUCOSAMINE....

Receptors, Natural Cytotoxicity Triggering - A subclass of natural killer cell receptors that perform an important role in the recognition of tum...

Receptors, Natural Killer Cell - Receptors that are specifically found on the surface of NATURAL KILLER CELLS. They play an important...

Receptors, Nerve Growth Factor - Cell surface receptors that bind NERVE GROWTH FACTOR; (NGF) and a NGF-related family of neurotrophic...

Receptors, Neurokinin-1 - A class of cell surface receptors for tachykinins with a preference for substance P. Neurokinin-1 (N...

Receptors, Neurokinin-2 - A class of cell surface receptors for tachykinins that prefers neurokinin A; (NKA, substance K, neur...

Receptors, Neurokinin-3 - A class of cell surface receptors for tachykinins that prefers neurokinin B (neurokinin beta, neurom...

Receptors, Neuropeptide - Cell surface receptors that bind specific neuropeptides with high affinity and trigger intracellular...

Receptors, Neuropeptide Y - Cell surface proteins that bind neuropeptide Y with high affinity and trigger intracellular changes ...

Receptors, Neurotensin - Cell surface proteins that bind neurotensin with high affinity and trigger intracellular changes whi...

Receptors, Neurotransmitter - Cell surface receptors that bind signalling molecules released by neurons and convert these signals ...

Receptors, Nicotinic - One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distingui...

Receptors, NK Cell Lectin-Like - Stucturally-related receptors that are typically found on NATURAL KILLER CELLS. They are considered ...

Receptors, N-Methyl-D-Aspartate - A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA r...

Receptors, Notch - A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their e...

Receptors, Odorant - Proteins, usually projecting from the cilia of olfactory receptor neurons, that specifically bind od...

Receptors, Oncostatin M - Cell surface receptors with specificity for ONCOSTATIN M. Two subtypes of receptors have been identi...

Receptors, Oncostatin M, Type II - A subtype of oncostatin receptors that are formed by dimerization of ONCOSTATIN M RECEPTOR BETA SUBU...

Receptors, Opioid - Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behav...

Receptors, Opioid, delta - A class of opioid receptors recognized by its pharmacological profile. Delta opioid receptors bind e...

Receptors, Opioid, kappa - A class of opioid receptors recognized by its pharmacological profile. Kappa opioid receptors bind d...

Receptors, Opioid, mu - A class of opioid receptors recognized by its pharmacological profile. Mu opioid receptors bind, in ...

Receptors, OSM-LIF - Cell surface receptors formed from the dimerization of LIF RECEPTOR ALPHA SUBUNIT with CYTOKINE RECE...

Receptors, OX40 - A tumor necrosis family receptor with specificity for OX40 LIGAND. It is found on the surface of act...

Receptors, Oxidized LDL - A group of cell-surface receptors for oxidatively modified LOW-DENSITY LIPOPROTEINS. The group inclu...

Receptors, Oxytocin - Cell surface proteins that bind oxytocin with high affinity and trigger intracellular changes which ...

Receptors, Pancreatic Hormone - Cell surface proteins that bind pancreatic hormones with high affinity and trigger intracellular cha...

Receptors, Parathyroid Hormone - Cell surface proteins that bind PARATHYROID HORMONE with high affinity and trigger intracellular cha...

Receptors, Pattern Recognition - A large family of cell surface receptors that bind conserved molecular structures present in pathoge...

Receptors, Peptide - Cell surface receptors that bind peptide messengers with high affinity and regulate intracellular si...

Receptors, Phencyclidine - Specific sites or molecular structures on cell membranes or in cells with which phencyclidine reacts...

Receptors, Pheromone - Cell surface receptors that respond to PHEROMONES....

Receptors, Phospholipase A2 - Cell surface receptors that bind to and internalize SECRETED PHOSPHOLIPASES A2. Although primarily a...

Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide - A family of G-protein-coupled receptors that share significant homology with GLUCAGON RECEPTORS. The...

Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - A pituitary adenylate cyclase-activating peptide receptor subtype that is found in the HYPOTHALAMUS;...

Receptors, Pituitary Hormone - Cell surface proteins that bind pituitary hormones with high affinity and trigger intracellular chan...

Receptors, Pituitary Hormone-Regulating Hormone - Cell surface receptors that bind the hypothalamic hormones regulating pituitary cell differentiation...

Receptors, Platelet-Derived Growth Factor - Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or...

Receptors, Polymeric Immunoglobulin - Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis o...

Receptors, Presynaptic - Neurotransmitter receptors located on or near presynaptic terminals or varicosities. Presynaptic rec...

Receptors, Progesterone - Specific proteins found in or on cells of progesterone target tissues that specifically combine with...

Receptors, Prolactin - Labile proteins on or in prolactin-sensitive cells that bind prolactin initiating the cells' physiol...

Receptors, Prostaglandin - Cell surface receptors that bind prostaglandins with high affinity and trigger intracellular changes...

Receptors, Prostaglandin E - Cell surface receptors which bind prostaglandins with a high affinity and trigger intracellular chan...

Receptors, Proteinase-Activated - A class of receptors that are activated by the action of PROTEINASES. The most notable examples are ...

Receptors, Purinergic - Cell surface proteins that bind PURINES with high affinity and trigger intracellular changes which i...

Receptors, Purinergic P1 - A class of cell surface receptors that prefers ADENOSINE to other endogenous purines. Purinergic P1 ...

Receptors, Purinergic P2 - A class of cell surface receptors for purines that prefer ATP or ADP over adenosine. P2 purinergic r...

Receptors, Retinoic Acid - Proteins in the nucleus or cytoplasm that specifically bind RETINOIC ACID or RETINOL and trigger cha...

Receptors, Scavenger - A large group of structurally diverse cell surface receptors that mediate endocytic uptake of modifi...

Receptors, Serotonin - Cell-surface proteins that bind SEROTONIN and trigger intracellular changes which influence the beha...

Receptors, Serotonin, 5-HT1 - A subclass of G-protein coupled SEROTONIN receptors that couple preferentially to GI-GO G-PROTEINS r...

Receptors, Serotonin, 5-HT2 - A subclass of G-protein coupled SEROTONIN receptors that couple preferentialy to the GQ-G11 G-PROTEI...

Receptors, Serotonin, 5-HT3 - A subclass of serotonin receptors that form cation channels and mediate signal transduction by depol...

Receptors, Serotonin, 5-HT4 - A subtype of G-protein-coupled SEROTONIN receptors that preferentially couple to GS STIMULATORY G-PR...

Receptors, sigma - A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were or...

Receptors, Somatomedin - Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the ...

Receptors, Somatostatin - Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the b...

Receptors, Somatotropin - Cell surface proteins that bind GROWTH HORMONE with high affinity and trigger intracellular changes ...

Receptors, Steroid - Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigg...

Receptors, Tachykinin - Cell surface proteins that bind tachykinins with high affinity and trigger intracellular changes inf...

Receptors, Thrombin - A family of proteinase-activated receptors that are specific for THROMBIN. They are found primarily ...

Receptors, Thrombopoietin - Cell surface receptors that are specific for THROMBOPOIETIN. They signal through interaction with JA...

Receptors, Thromboxane - Cell surface proteins that bind THROMBOXANES with high affinity and trigger intracellular changes in...

Receptors, Thromboxane A2, Prostaglandin H2 - A subclass of eicosanoid receptors that have specificity for THROMBOXANE A2 and PROSTAGLANDIN H2....

Receptors, Thyroid Hormone - Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found...

Receptors, Thyrotropin - Cell surface proteins that bind pituitary THYROTROPIN (also named thyroid stimulating hormone or TSH...

Receptors, Thyrotropin-Releasing Hormone - Cell surface receptors that bind thyrotropin releasing hormone (TRH) with high affinity and trigger ...

Receptors, TIE - A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOT...

Receptors, TNF-Related Apoptosis-Inducing Ligand - Tumor necrosis factor receptor family members that are widely expressed and play a role in regulatio...

Receptors, Transferrin - Membrane glycoproteins found in high concentrations on iron-utilizing cells. They specifically bind ...

Receptors, Transforming Growth Factor beta - Cell-surface proteins that bind transforming growth factor beta and trigger changes influencing the ...

Receptors, Tumor Necrosis Factor - Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the beha...

Receptors, Tumor Necrosis Factor, Member 10c - A secreted tumor necrosis factor receptor family member that has specificity for TNF-RELATED APOPTOS...

Receptors, Tumor Necrosis Factor, Member 14 - A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIR...

Receptors, Tumor Necrosis Factor, Member 25 - A tumor necrosis factor receptor subtype with specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMI...

Receptors, Tumor Necrosis Factor, Member 6b - A secreted tumor necrosis factor receptor family member that has specificity FAS LIGAND and TUMOR NE...

Receptors, Tumor Necrosis Factor, Type I - A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LY...

Receptors, Tumor Necrosis Factor, Type II - A tumor necrosis factor receptor subtype that is expressed primarily in IMMUNE SYSTEM cells. It has ...

Receptors, Urokinase Plasminogen Activator - An extracellular receptor specific for UROKINASE-TYPE PLASMINOGEN ACTIVATOR. It is attached to the c...

Receptors, Vascular Endothelial Growth Factor - A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth ...

Receptors, Vasoactive Intestinal Peptide - Cell surface proteins that bind VASOACTIVE INTESTINAL PEPTIDE; (VIP); with high affinity and trigger...

Receptors, Vasoactive Intestinal Peptide, Type II - A pituitary adenylate cyclase-activating peptide receptor subtype found in LYMPHOCYTES. It binds bot...

Receptors, Vasoactive Intestinal Polypeptide, Type I - A pituitary adenylate cyclase-activating polypeptide receptor subtype that binds both PACAP and VASO...

Receptors, Vasopressin - Specific molecular sites or proteins on or in cells to which VASOPRESSINS bind or interact in order ...

Receptors, Very Late Antigen - Members of the integrin family appearing late after T-cell activation. They are a family of proteins...

Receptors, Virus - Specific molecular components of the cell capable of recognizing and interacting with a virus, and w...

Receptors, Vitronectin - Receptors such as INTEGRIN ALPHAVBETA3 that bind VITRONECTIN with high affinity and play a role in c...

Recombinant Fusion Proteins - Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of...

Recombinant Proteins - Proteins prepared by recombinant DNA technology....

Recoverin - A neuronal calcium-sensor protein that is found in ROD PHOTORECEPTORS and CONE PHOTORECEPTORS. It in...

Replication Protein A - A single-stranded DNA-binding protein that is found in EUKARYOTIC CELLS. It is required for DNA REPL...

Replication Protein C - A DNA-binding protein that consists of 5 polypeptides and plays an essential role in DNA REPLICATION...

Repressor Proteins - Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repre...

Reptilian Proteins - Proteins obtained from species of REPTILES....

Resistin - A 12-kDa cysteine-rich polypeptide hormone secreted by FAT CELLS in the ADIPOSE TISSUE. It is the fo...

Reticulin - A scleroprotein fibril consisting mostly of type III collagen. Reticulin fibrils are extremely thin,...

Retinal Dehydrogenase - A metalloflavoprotein enzyme involved the metabolism of VITAMIN A, this enzyme catalyzes the oxidati...

Retinoblastoma Binding Proteins - A family of endogenous regulatory proteins that associate with RETINOBLASTOMA PROTEIN via a specific...

Retinoblastoma Protein - Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to ...

Retinoblastoma-Binding Protein 1 - A ubiquitously expressed regulatory protein that contains a retinoblastoma protein binding domain an...

Retinoblastoma-Binding Protein 2 - A retinoblastoma binding protein that is also a member of the Jumonji-domain histone demethylases. I...

Retinoblastoma-Binding Protein 4 - A retinoblastoma-binding protein that is involved in CHROMATIN REMODELING, histone deacetylation, an...

Retinoblastoma-Binding Protein 7 - A retinoblastoma-binding protein that is found as a subunit of protein complexes involved in the ace...

Retinoblastoma-Like Protein p107 - A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. I...

Retinoblastoma-Like Protein p130 - A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. R...

Retinoid X Receptor alpha - A nuclear transcription factor. Heterodimerization with PPAR GAMMA is important in regulation of GLU...

Retinoid X Receptor gamma - A nuclear transcription factor. Heterodimerization with PPAR ALPHA is important to metabolism of LIP...

Retinoid X Receptors - A subtype of RETINOIC ACID RECEPTORS that are specific for 9-cis-retinoic acid which function as nuc...

Retinol-Binding Proteins - Proteins which bind with RETINOL. The retinol-binding protein found in plasma has an alpha-1 mobilit...

Retinol-Binding Proteins, Cellular - A subclass of retinol-binding proteins that take part in the intracellular storage and transport of ...

Retinol-Binding Proteins, Plasma - Retinol binding proteins that circulate in the PLASMA. They are members of the lipocalin family of p...

Retroviridae Proteins - Proteins from the family Retroviridae. The most frequently encountered member of this family is the ...

Retroviridae Proteins, Oncogenic - Retroviral proteins that have the ability to transform cells. They can induce sarcomas, leukemias, l...

rev Gene Products, Human Immunodeficiency Virus - Proteins encoded by the REV GENES of the HUMAN IMMUNODEFICIENCY VIRUS....

RGS Proteins - A large family of evolutionarily conserved proteins that function as negative regulators of HETEROTR...

Rheumatoid Factor - Antibodies found in adult RHEUMATOID ARTHRITIS patients that are directed against GAMMA-CHAIN IMMUNO...

Rho Factor - A protein which effects termination of RNA synthesis during the genetic transcription process by dis...

rho GTP-Binding Proteins - A large family of MONOMERIC GTP-BINDING PROTEINS that are involved in regulation of actin organizati...

Rho(D) Immune Globulin - Immunizing agent containing IMMUNOGLOBULIN G anti-Rho(D) used for preventing Rh immunization in Rh-n...

rhoA GTP-Binding Protein - A RHO GTP-BINDING PROTEIN involved in regulating signal transduction pathways that control assembly ...

rho-Associated Kinases - A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. T...

rhoB GTP-Binding Protein - A GTP-BINDING PROTEIN involved in regulating a signal transduction pathway that controls assembly of...

Rhodopsin - A purplish-red, light-sensitive pigment found in RETINAL ROD CELLS of most vertebrates. It is a comp...

Rhodopsins, Microbial - Rhodopsin molecules found in microorganisms such as ARCHAEA and PROTEOBACTERIA....

Ribonuclease H, Human Immunodeficiency Virus - A ribonuclease activity that is a component of the HIV REVERSE TRANSCRIPTASE. It removes the RNA str...

Ribonuclease P - An RNA-containing enzyme that plays an essential role in tRNA processing by catalyzing the endonucle...

Ribonucleoprotein, U1 Small Nuclear - A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP ...

Ribonucleoprotein, U2 Small Nuclear - A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U2 snRNP ...

Ribonucleoprotein, U4-U6 Small Nuclear - A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U4-U6 snR...

Ribonucleoprotein, U5 Small Nuclear - A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U5 snRNP ...

Ribonucleoprotein, U7 Small Nuclear - This ribonucleoprotein particle, composed of U7 snRNA, Sm core protein, and U7 snRNP-specific protei...

Ribonucleoproteins - Complexes of RNA-binding proteins with ribonucleic acids (RNA)....

Ribonucleoproteins, Small Cytoplasmic - Complexes of scRNA (RNA, SMALL CYTOPLASMIC) and protein found in the cytoplasm. An example is SIGNAL...

Ribonucleoproteins, Small Nuclear - Highly conserved nuclear RNA-protein complexes that function in RNA processing in the nucleus, inclu...

Ribonucleoproteins, Small Nucleolar - Nucleolar RNA-protein complexes that function in pre-ribosomal RNA processing....

Ribosomal Protein S6 - A ribosomal protein that may play a role in controlling cell growth and proliferation. It is a major...

Ribosomal Protein S6 Kinases - A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ri...

Ribosomal Protein S6 Kinases, 70-kDa - A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIB...

Ribosomal Protein S6 Kinases, 90-kDa - A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN ...

Ribosomal Proteins - Proteins found in ribosomes. They are believed to have a catalytic function in reconstituting biolog...

Ribosome Inactivating Proteins - N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop...

Ribosome Inactivating Proteins, Type 1 - Ribosome inactivating proteins consisting of only the toxic A subunit, which is a polypeptide of aro...

Ribosome Inactivating Proteins, Type 2 - Ribosome inactivating proteins consisting of two polypeptide chains, the toxic A subunit and a lecti...

Ricin - A protein phytotoxin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells...

RNA Cap-Binding Proteins - Proteins that specifically bind to RNA CAPS and form nuclear cap binding protein complexes. In addit...

RNA Polymerase Sigma 54 - A DNA-directed RNA polymerase found in BACTERIA. It is a holoenzyme that consists of multiple subuni...

RNA-Binding Protein EWS - A ubiquitous hnRNP protein found in the CELL NUCLEUS and the CYTOPLASM. Translocations that result i...

RNA-Binding Protein FUS - A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pai...

RNA-Binding Proteins - Proteins that bind to RNA molecules. Included here are RIBONUCLEOPROTEINS and other proteins whose f...

RNA-Directed DNA Polymerase - An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and...

RNA-Induced Silencing Complex - A multicomponent, ribonucleoprotein complex that cleaves specific mRNAs (RNA, MESSENGER) which are t...

Rod Opsins - Photosensitive proteins expressed in the ROD PHOTORECEPTOR CELLS. They are the protein components of...

R-SNARE Proteins - SNARE proteins where the central amino acid residue of the SNARE motif is an ARGININE. They are clas...

Rubredoxins - A class of iron-sulfur proteins that contains one iron coordinated to the sulfur atom of four cystei...

Ryanodine Receptor Calcium Release Channel - A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, ...

S100 Proteins - A family of highly acidic calcium-binding proteins found in large concentration in the brain and bel...

Saccharomyces cerevisiae Proteins - Proteins obtained from the species SACCHAROMYCES CEREVISIAE. The function of specific proteins from ...

Salivary alpha-Amylases - A subclass of alpha-amylase ISOENZYMES that are secreted into SALIVA....

Salivary Cystatins - A group of closely-related cystatins found in SALIVA....

Salivary Proline-Rich Proteins - A family of proline-rich proteins that constitute the majority of the protein component of SALIVA. S...

Salivary Proteins and Peptides - Proteins and peptides found in SALIVA and the SALIVARY GLANDS. Some salivary proteins such as ALPHA-...

Sarcoglycans - A family of transmembrane dystrophin-associated proteins that plays a role in the membrane associati...

Sarcoplasmic Reticulum Calcium-Transporting ATPases - Calcium-transporting ATPases that catalyze the active transport of CALCIUM into the SARCOPLASMIC RET...

Sarcosine Oxidase - A FLAVOPROTEIN, this enzyme catalyzes the oxidation of SARCOSINE to GLYCINE; FORMALDEHYDE; and HYDRO...

Scavenger Receptors, Class A - A family of scavenger receptors that mediate the influx of LIPIDS into MACROPHAGES and are involved ...

Scavenger Receptors, Class B - A family of scavenger receptors that are predominately localized to CAVEOLAE of the PLASMA MEMBRANE ...

Scavenger Receptors, Class C - A family of scavenger receptors with broad polyanionic ligand binding properties that are expressed ...

Scavenger Receptors, Class D - A class of scavenger receptors that are specific for oxidized LOW-DENSITY LIPOPROTEINS and apoptotic...

Scavenger Receptors, Class E - A class of oxidized LDL receptors that contain LECTIN-like extracellular domains....

Scavenger Receptors, Class F - A group of structurally related scavenger receptors expressed predominately by ENDOTHELIAL CELLS. Th...

Schizosaccharomyces pombe Proteins - Proteins obtained from the species Schizosaccharomyces pombe. The function of specific proteins from...

Scleroproteins - Simple proteins characterized by their insolubility and fibrous structure. Within the body, they per...

Secretin - A peptide hormone of about 27 amino acids from the duodenal mucosa that activates pancreatic secreti...

Secretogranin II - A type of chromogranin which was initially characterized in the ANTERIOR PITUITARY GLAND. It is foun...

Secretory Component - The extracellular moiety of the POLYMERIC IMMUNOGLOBULIN RECEPTOR found alone or complexed with IGA ...

Secretory Leukocyte Peptidase Inhibitor - A proteinase inhibitor found in various BODILY SECRETIONS that coat mucosal surfaces such as SEMINAL...

Seed Storage Proteins - One or more types of plant seed proteins providing the large amounts of AMINO ACIDS utilized in GERM...

Selectins - Family of cell adhesion molecules consisting of a lectin-like domain, an epidermal growth factor-lik...

Selenium-Binding Proteins - A group of proteins that covalently attach to selenium or SELENIUM-containing compounds....

Selenoprotein P - An extracellular selenoprotein that contains most of the SELENIUM in PLASMA. Selenoprotein P functio...

Selenoprotein W - A single SELENOCYSTEINE containing protein that binds reduced GLUTATHIONE and can act as an antioxid...

Selenoproteins - Selenoproteins are proteins that specifically incorporate SELENOCYSTEINE into their amino acid chain...

Semaphorin-3A - The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-rep...

Semaphorins - A family of proteins that mediate axonal guidance. Semaphorins act as repulsive cues for neuronal G...

Seminal Plasma Proteins - Proteins found in SEMEN. Major seminal plasma proteins are secretory proteins from the male sex acce...

Seminal Vesicle Secretory Proteins - The secretory proteins of the seminal vesicles are proteins and enzymes that are important in the ra...

Sensory Rhodopsins - Photosensory rhodopsins found in microorganisms such as HALOBACTERIA. They convert light signals int...

Sericins - A serine-rich sticky protein secreted by MOTHS. Generally, the term refers to silkworm silk gum prot...

Sermorelin - The biologically active fragment of human growth hormone-releasing factor, consisting of GHRH(1-29)-...

Serotonin Plasma Membrane Transport Proteins - Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of se...

Serpins - A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of i...

Serum Albumin - A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and tran...

Serum Albumin, Bovine - Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)...

Serum Albumin, Radio-Iodinated - Normal human serum albumin mildly iodinated with radioactive iodine (131-I) which has a half-life of...

Serum Amyloid A Protein - An ACUTE PHASE REACTION protein present in low concentrations in normal sera, but found at higher co...

Serum Amyloid P-Component - Amyloid P component is a small, non-fibrillar glycoprotein found in normal serum and in all amyloid ...

Serum Globulins - All blood proteins except albumin ( = SERUM ALBUMIN, which is not a globulin) and FIBRINOGEN (which ...

Serum Response Factor - A MADS domain-containing transcription factor that binds to the SERUM RESPONSE ELEMENT in the promot...

Sex Hormone-Binding Globulin - A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicat...

Sex-Determining Region Y Protein - A transcription factor that plays an essential role in the development of the TESTES. It is encoded ...

SH2 Domain-Containing Protein Tyrosine Phosphatases - A subcategory of protein tyrosine phosphatases that contain SH2 type SRC HOMOLOGY DOMAINS. Many of t...

Shab Potassium Channels - A subfamily of shaker potassium channels that shares homology with its founding member, Shab protein...

Shaker Superfamily of Potassium Channels - Voltage-gated potassium channels whose primary subunits contain six transmembrane segments and form ...

Shal Potassium Channels - A shaker subfamily of potassium channels that participate in transient outward potassium currents by...

Shaw Potassium Channels - A shaker subfamily that is prominently expressed in NEURONS and are necessary for high-frequency, re...

Shc Signaling Adaptor Proteins - A family of signaling adaptor proteins that contain SRC HOMOLOGY DOMAINS. Many members of this famil...

Shiga Toxin 1 - A toxin produced by certain pathogenic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157. It...

Shiga Toxin 2 - A toxin produced by certain pathogenic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157. It...

Sialoglycoproteins - Glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in...

Sialomucins - A subcategory of mucins that contain SIALIC ACID....

Sigma Factor - A protein which is a subunit of RNA polymerase. It effects initiation of specific RNA chains from DN...

Signal Recognition Particle - A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory ...

Silent Information Regulator Proteins, Saccharomyces cerevisiae - A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repr...

Silk - A continuous protein fiber consisting primarily of FIBROINS. It is synthesized by a variety of INSEC...

Silver Proteins - Compounds of silver and proteins used as topical anti-infective agents....

Sin3 Histone Deacetylase and Corepressor Complex - A multisubunit enzyme complex that regulates GENETIC TRANSCRIPTION by deacetylating the HISTONE resi...

Single-Chain Antibodies - A form of antibodies (scFv) consisting of the variable regions of only the heavy and light chains, c...

Sirtuin 1 - A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with...

Sirtuin 2 - A sirtuin family member found primarily in the CYTOPLASM. It is a multifunctional enzyme that contai...

Sirtuin 3 - A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contain...

Sirtuins - A homologous family of regulatory enzymes that are structurally related to the protein silent mating...

Skeletal Muscle Myosins - Myosin type II isoforms found in skeletal muscle....

Smad Proteins - A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE...

Smad Proteins, Inhibitory - A sub-family of smad proteins that inhibit cell signaling by RECEPTOR-REGULATED SMAD PROTEINS. They ...

Smad Proteins, Receptor-Regulated - A family of smad proteins that undergo PHOSPHORYLATION by CELL SURFACE RECEPTORS in response to TRAN...

Smad1 Protein - A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEP...

Smad2 Protein - A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. It re...

Smad3 Protein - A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. Activ...

Smad4 Protein - A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated...

Smad5 Protein - A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEP...

Smad6 Protein - An inhibitory Smad protein that negatively regulates the SIGNAL TRANSDUCTION PATHWAYS from BONE MORP...

Smad7 Protein - An inhibitory smad protein that associates with TRANSFORMING GROWTH FACTOR BETA RECEPTORS and BONE M...

Smad8 Protein - A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEP...

Small Ubiquitin-Related Modifier Proteins - A class of structurally related proteins of 12-20 kDa in size. They covalently modify specific prote...

Small-Conductance Calcium-Activated Potassium Channels - A major class of calcium-activated potassium channels that are found primarily in excitable CELLS. T...

SMN Complex Proteins - A complex of proteins that assemble the SNRNP CORE PROTEINS into a core structure that surrounds a h...

Smooth Muscle Myosins - Myosin type II isoforms found in smooth muscle....

SNARE Proteins - A superfamily of small proteins which are involved in the MEMBRANE FUSION events, intracellular prot...

snRNP Core Proteins - The protein components that constitute the common core of small nuclear ribonucleoprotein particles....

Sodium Channels - Cell membrane glycoproteins selective for sodium ions. Fast sodium current is associated with the ac...

Sodium Chloride Symporters - A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorpt...

Sodium-Bicarbonate Symporters - Proteins that cotransport sodium ions and bicarbonate ions across cellular membranes....

Sodium-Calcium Exchanger - An electrogenic ion exchange protein that maintains a steady level of calcium by removing an amount ...

Sodium-Glucose Transport Proteins - Monosaccharide transport proteins that function as active symporters. They utilize SODIUM or HYDROGE...

Sodium-Glucose Transporter 1 - The founding member of the sodium glucose transport proteins. It is predominately expressed in the I...

Sodium-Glucose Transporter 2 - A sodium-glucose transporter that is expressed in the luminal membrane of the PROXIMAL KIDNEY TUBULE...

Sodium-Hydrogen Antiporter - A plasma membrane exchange glycoprotein transporter that functions in intracellular pH regulation, c...

Sodium-Phosphate Cotransporter Proteins - A family of symporters that facilitate sodium-dependent membrane transport of phosphate....

Sodium-Phosphate Cotransporter Proteins, Type I - A family of sodium-phosphate cotransporter proteins that also transport organic ANIONS. They are low...

Sodium-Phosphate Cotransporter Proteins, Type II - A family of sodium-phosphate cotransporter proteins with eight transmembrane domains. They are prese...

Sodium-Phosphate Cotransporter Proteins, Type IIa - An electrogenic sodium-dependent phosphate transporter. It is present primarily in BRUSH BORDER memb...

Sodium-Phosphate Cotransporter Proteins, Type IIb - A sodium-dependent phosphate transporter present primarily at apical sites of EPITHELIAL CELLS in th...

Sodium-Phosphate Cotransporter Proteins, Type IIc - A non-electrogenic sodium-dependent phosphate transporter. It is found primarily in apical membranes...

Sodium-Phosphate Cotransporter Proteins, Type III - A family of highly conserved and widely expressed sodium-phosphate cotransporter proteins. They are ...

Sodium-Potassium-Chloride Symporters - A subclass of symporters that specifically transport SODIUM CHLORIDE and POTASSIUM CHLORIDE across c...

Sodium-Potassium-Exchanging ATPase - An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wa...

Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins - SNARE binding proteins that facilitate the ATP hydrolysis-driven dissociation of the SNARE complex. ...

Somatomedins - Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when st...

Somatostatin - A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also call...

Somatostatin-28 - A 28-amino acid peptide with the same biological activities of somatostatin-14 but with a 14-amino a...

Son of Sevenless Protein, Drosophila - A guanine nucleotide exchange factor from DROSOPHILA. Sevenless refers to genetic mutations in DROSO...

Son of Sevenless Proteins - A class of RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS that are genetically related to the Son of Sevenl...

SOS1 Protein - A mammalian homolog of the DROSOPHILA SON OF SEVENLESS PROTEIN. It is a guanine nucleotide exchange ...

SOX Transcription Factors - A large family of structurally-related transcription factors that were originally discovered based u...

SOX9 Transcription Factor - A SOXE transcription factor that plays a critical role in regulating CHONDROGENESIS; OSTEOGENESIS; a...

SOXB1 Transcription Factors - A subclass of SOX transcription factors that are expressed in neuronal tissue where they may play a ...

SOXB2 Transcription Factors - A subclass of SOX transcription factors that are expressed in neuronal tissue where they may play a ...

SOXC Transcription Factors - A subclass of closely-related SOX transcription factors. Members of the group have been found expres...

SOXD Transcription Factors - A subclass of closely-related SOX transcription factors. In addition to a conserved HMG-BOX DOMAIN, ...

SOXE Transcription Factors - A subclass of closely-related SOX transcription factors. Members of this subfamily have been implica...

SOXF Transcription Factors - A subclass of closely-related SOX transcription factors. Members of this subclass are expressed in V...

Soybean Proteins - Proteins which are present in or isolated from SOYBEANS....

Sp Transcription Factors - A family of DNA-binding proteins that contain three ZINC FINGERS at their carboxy termini. They are ...

Sp1 Transcription Factor - Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstre...

Sp2 Transcription Factor - A ubiquitously expressed Sp transcription factor that binds to the consensus DNA sequence GGGCGGGAC....

Sp3 Transcription Factor - A specificity protein transcription factor that regulates expression of a variety of genes including...

Sp4 Transcription Factor - A specificity protein transcription factor that is expressed primarily in the CENTRAL NERVOUS SYSTEM...

Spectrin - A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ...

S-Phase Kinase-Associated Proteins - A family of structurally-related proteins that were originally identified by their ability to comple...

Staphylococcal Protein A - A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively bi...

STAT Transcription Factors - A family of transcription factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated SIGN...

STAT1 Transcription Factor - A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. ...

STAT2 Transcription Factor - A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERF...

STAT3 Transcription Factor - A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6...

STAT4 Transcription Factor - A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-1...

STAT5 Transcription Factor - A signal transducer and activator of transcription that mediates cellular responses to a variety of ...

STAT6 Transcription Factor - A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-4...

Stathmin - A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSD...

Stem Cell Factor - A hematopoietic growth factor and the ligand of the cell surface c-kit protein (PROTO-ONCOGENE PROTE...

Steroid 11-beta-Hydroxylase - A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the p...

Steroid 12-alpha-Hydroxylase - A liver microsomal cytochrome P450 enzyme that catalyzes the 12-alpha-hydroxylation of a broad spect...

Steroid 16-alpha-Hydroxylase - A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spect...

Steroid 17-alpha-Hydroxylase - A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pre...

Steroid 21-Hydroxylase - An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the ...

Steroid Hydroxylases - Cytochrome P-450 monooxygenases (MIXED FUNCTION OXYGENASES) that are important in steroid biosynthes...

Steroidogenic Factor 1 - A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout th...

Sterol Regulatory Element Binding Protein 1 - A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACI...

Sterol Regulatory Element Binding Protein 2 - A sterol regulatory element binding protein that regulates GENES involved in CHOLESTEROL synthesis a...

Sterol Regulatory Element Binding Proteins - Sterol regulatory element binding proteins are basic helix-loop-helix leucine zipper transcription f...

Streptavidin - A 60-kDa extracellular protein of Streptomyces avidinii with four high-affinity biotin binding sites...

Streptodornase and Streptokinase - A mixture of the enzymes (streptokinase and streptodornase) produced by hemolytic streptococci. It i...

Streptokinase - Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linka...

Streptolysins - Exotoxins produced by certain strains of streptococci, particularly those of group A (STREPTOCOCCUS ...

Substance P - An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous system...

Succinate Dehydrogenase - A flavoprotein containing oxidoreductase that catalyzes the dehdyrogenation of SUCCINATE to fumerate...

SUMO-1 Protein - A 1.5-kDa small ubiquitin-related modifier protein that can covalently bind via an isopeptide link t...

Suppressor Factors, Immunologic - Proteins, protein complexes, or glycoproteins secreted by suppressor T-cells that inhibit either sub...

Suppressor of Cytokine Signaling Proteins - A family of structurally related proteins that are induced by CYTOKINES and negatively regulate cyto...

Survival of Motor Neuron 1 Protein - A SMN complex protein that is essential for the function of the SMN protein complex. In humans the p...

Survival of Motor Neuron 2 Protein - A SMN complex protein that is closely-related to SURVIVAL OF MOTOR NEURON 1 PROTEIN. In humans, the ...

Symporters - Membrane transporters that co-transport two or more dissimilar molecules in the same direction acros...

Synapsins - A family of synaptic vesicle-associated proteins involved in the short-term regulation of NEUROTRANS...

Synaptophysin - A 38-kDa integral membrane glycoprotein of the presynaptic vesicles in neuron and neuroendocrine cel...

Synaptosomal-Associated Protein 25 - A ubiquitous target SNARE protein that interacts with SYNTAXIN and SYNAPTOBREVIN. It is a core compo...

Synaptotagmin I - A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCY...

Synaptotagmin II - A vesicular transport protein that was originally characterized as an inositol polyphosphate binding...

Synaptotagmins - A family of vesicular transport proteins characterized by an N-terminal transmembrane region and two...

Syndecan-1 - A syndecan that interacts with EXTRACELLULAR MATRIX PROTEINS and plays a role CELL PROLIFERATION and...

Syndecan-2 - A syndecan that is predominantly expressed during EMBRYONIC DEVELOPMENT. It may play a role in media...

Syndecan-3 - A syndecan found at high levels in the developing LIMB BUDS. It may play a role in the regulation of...

Syndecan-4 - A ubiquitously expressed syndecan that is found in all stages of embryonic development and in most a...

Syndecans - A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span trans...

Syntaxin 1 - A neuronal cell membrane protein that combines with SNAP-25 and SYNAPTOBREVIN 2 to form a SNARE comp...

Syntaxin 16 - A ubiquitously expressed member of the syntaxin subfamily of SNARE proteins that localizes to the GO...

Syntenins - Intracellular signaling adaptor proteins that play a role in the coupling of SYNDECANS to CYTOSKELET...

Synucleins - A family of homologous proteins of low MOLECULAR WEIGHT that are predominately expressed in the BRAI...

T Cell Transcription Factor 1 - A TCF transcription factor that was originally identified as a DNA-binding protein that interacts wi...

Tachykinins - A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-...

Tacrolimus Binding Protein 1A - A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of c...

Tacrolimus Binding Proteins - A family of immunophilin proteins that bind to the immunosuppressive drugs TACROLIMUS (also known as...

Talin - A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of c...

tat Gene Products, Human Immunodeficiency Virus - Proteins encoded by the TAT GENES of the HUMAN IMMUNODEFICIENCY VIRUS....

TATA Box Binding Protein-Like Proteins - A class of proteins related in structure and function to TATA-BOX BINDING PROTEIN that can take the ...

TATA-Binding Protein Associated Factors - Factors that associate with TATA-BOX BINDING PROTEIN. Many of them are components of TRANSCRIPTION F...

TATA-Box Binding Protein - A general transcription factor that plays a major role in the activation of eukaryotic genes transcr...

tau Proteins - Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute severa...

tau-Crystallins - A type of crystallin that has been found in the lens (LENS, CRYSTALLINE) of certain species of VERTE...

T-Box Domain Proteins - Proteins containing a region of conserved sequence, about 200 amino acids long, which encodes a part...

TCF Transcription Factors - A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with B...

Technetium Tc 99m Aggregated Albumin - A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, part...

Telomerase - An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryot...

Telomere-Binding Proteins - Proteins that specifically bind to TELOMERES. Proteins in this class include those that perform func...

Telomeric Repeat Binding Protein 1 - A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL C...

Telomeric Repeat Binding Protein 2 - A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the cell c...

Tenascin - Hexameric extracellular matrix glycoprotein transiently expressed in many developing organs and ofte...

Ternary Complex Factors - A subclass of c-ets proto-oncogene proteins that were first described by their property of binding t...

Tetanus Antitoxin - An antitoxin used for the treatment of TETANUS....

Tetanus Toxin - Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity t...

TGF-beta Superfamily Proteins - A large family of cell regulatory proteins which are structurally related to TRANSFORMING GROWTH FAC...

Thermosomes - Group II chaperonins found in species of ARCHAEA....

Thionins - Antimicrobial peptides of 45-47 amino acids and typically with four disulfide bridges. They are foun...

Thioredoxin h - A thioredoxin subtype that is ubiquitously found in the plant kingdom. It reduces a variety of seed...

Thioredoxin-Disulfide Reductase - A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the p...

Thioredoxins - Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonuc...

Thrombin - An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN....

Thrombomodulin - A cell surface glycoprotein of endothelial cells that binds thrombin and serves as a cofactor in the...

Thromboplastin - Constituent composed of protein and phospholipid that is widely distributed in many tissues. It serv...

Thrombopoietin - A humoral factor that stimulates the production of thrombocytes (BLOOD PLATELETS). Thrombopoietin s...

Thrombospondin 1 - An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of...

Thrombospondins - A family of related, adhesive glycoproteins which are synthesized, secreted, and incorporated into t...

Thymosin - Thymosin. A family of heat-stable, polypeptide hormones secreted by the thymus gland. Their biologic...

Thyroid Hormone Receptors alpha - High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usual...

Thyroid Hormone Receptors beta - High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usual...

Thyrotropin-Releasing Hormone - A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neur...

Thyroxine-Binding Globulin - A thyroid hormone transport protein found in serum. It binds about 75% of circulating THYROXINE and ...

Thyroxine-Binding Proteins - Blood proteins that bind to THYROID HORMONES such as THYROXINE and transport them throughout the cir...

Tissue Inhibitor of Metalloproteinase-1 - A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, mo...

Tissue Inhibitor of Metalloproteinase-2 - A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated pro...

Tissue Inhibitor of Metalloproteinase-3 - A member of the family of tissue inhibitor of metalloproteinases. Mutations of the gene for TIMP3 PR...

Tissue Inhibitor of Metalloproteinases - A family of secreted proteins (TIMP-1; TIMP-2; and TIMP-3) that play a crucial role in regulating th...

Tissue Plasminogen Activator - A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN ...

TNF Receptor-Associated Death Domain Protein - A 34 kDa signal transducing adaptor protein that associates with TUMOR NECROSIS FACTOR RECEPTOR TYPE...

TNF Receptor-Associated Factor 1 - A signal transducing tumor necrosis factor receptor associated factor that is involved in TNF RECEPT...

TNF Receptor-Associated Factor 2 - A signal transducing tumor necrosis factor receptor associated factor that is involved in TNF RECEPT...

TNF Receptor-Associated Factor 3 - A signal transducing tumor necrosis factor receptor associated factor that is involved in regulation...

TNF Receptor-Associated Factor 4 - A widely expressed member of the TNF receptor-associated family that may play a role in neuronal dev...

TNF Receptor-Associated Factor 5 - A signal transducing tumor necrosis factor receptor associated factor that mediates signaling from C...

TNF Receptor-Associated Factor 6 - A signal transducing tumor necrosis factor receptor associated factor that is involved in regulation...

TNF-Related Apoptosis-Inducing Ligand - A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a wid...

Toll-Like Receptor 1 - A pattern recognition receptor that forms heterodimers with TOLL-LIKE RECEPTOR 2....

Toll-Like Receptor 10 - A pattern recognition receptor that is expressed in LUNG and in B-LYMPHOCYTES....

Toll-Like Receptor 2 - A pattern recognition receptor that forms heterodimers with other TOLL-LIKE RECEPTORS. It interacts ...

Toll-Like Receptor 3 - A pattern recognition receptor that binds DOUBLE-STRANDED RNA. It mediates cellular responses to cer...

Toll-Like Receptor 4 - A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It...

Toll-Like Receptor 5 - A pattern recognition receptor that binds FLAGELLIN. It mediates cellular responses to certain bacte...

Toll-Like Receptor 6 - A pattern recognition receptor that forms heterodimers with TLR2 RECEPTOR. The complex interacts wit...

Toll-Like Receptor 7 - A pattern recognition receptor that binds several forms of imidazo-quinoline including the antiviral...

Toll-Like Receptor 8 - A pattern recognition receptor that recognizes GUANOSINE and URIDINE-rich single-stranded RNA....

Toll-Like Receptor 9 - A pattern recognition receptor that binds unmethylated CPG CLUSTERS. It mediates cellular responses ...

Toll-Like Receptors - A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and ...

Tolloid-Like Metalloproteinases - A family of metalloproteases that are related to the DROSOPHILA protein tolloid, which is a gene pro...

Trans-Activators - Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA t...

Transcobalamins - A group of carrier proteins which bind with VITAMIN B12 in the BLOOD and aid in its transport. Trans...

Transcortin - A serpin family member that binds to and transports GLUCOCORTICOIDS in the BLOOD....

Transcription Factor AP-1 - A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins m...

Transcription Factor AP-2 - A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFEREN...

Transcription Factor Brn-3 - A family of mammalian POU domain factors that are expressed predominately in NEURONS....

Transcription Factor Brn-3A - A POU domain factor that activates GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS; a...

Transcription Factor Brn-3B - A POU domain factor that represses GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS, a...

Transcription Factor Brn-3C - A POU domain factor that activates neuronal cell GENETIC TRANSCRIPTION of GENES encoding NEUROFILAME...

Transcription Factor CHOP - A CCAAT-enhancer binding protein that is induced by DNA DAMAGE and growth arrest. It serves as a dom...

Transcription Factor DP1 - A transcription factor that possesses DNA-binding and E2F-binding domains but lacks a transcriptiona...

Transcription Factor Pit-1 - A POU domain factor that regulates expression of GROWTH HORMONE; PROLACTIN; and THYROTROPIN-BETA in ...

Transcription Factor RelA - A subunit of NF-kappa B that is primarily responsible for its transactivation function. It contains ...

Transcription Factor RelB - A transcription factor that takes part in the NF-kappa-B complex by interacting with NF-KAPPA B P50 ...

Transcription Factor TFIIA - An RNA POLYMERASE II specific transcription factor. It may play a role in transcriptional activation...

Transcription Factor TFIIB - An RNA POLYMERASE II specific transcription factor. It plays a role in assembly of the pol II transc...

Transcription Factor TFIID - The major sequence-specific DNA-binding component involved in the activation of transcription of RNA...

Transcription Factor TFIIH - A general transcription factor that is involved in basal GENETIC TRANSCRIPTION and NUCLEOTIDE EXCISI...

Transcription Factor TFIIIA - One of several general transcription factors that are specific for RNA POLYMERASE III. It is a zinc ...

Transcription Factor TFIIIB - One of several general transcription factors that are specific for RNA POLYMERASE III. TFIIIB recrui...

Transcription Factors - Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or term...

Transcription Factors, General - Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRE...

Transcription Factors, TFII - The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to ...

Transcription Factors, TFIII - Factors that bind to RNA POLYMERASE III and aid in transcription. They include the assembly factors ...

Transcriptional Elongation Factors - Transcription factors whose primary function is to regulate the rate in which RNA is transcribed....

Transducin - A heterotrimeric GTP-binding protein that mediates the light activation signal from photolyzed rhodo...

Transfer Factor - Factor derived from leukocyte lysates of immune donors which can transfer both local and systemic ce...

Transferrin - Serum beta-globulin that binds and transports iron. (From Dorland, 28th ed)...

Transferrin-Binding Protein A - A subtype of bacterial transferrin-binding protein found in bacteria. It forms a cell surface recept...

Transferrin-Binding Protein B - A subtype of bacterial transferrin-binding protein found in bacteria. It forms a cell surface recept...

Transferrin-Binding Proteins - A class of carrier proteins that bind to TRANSFERRIN. Many strains of pathogenic bacteria utilize tr...

Transforming Growth Factor alpha - Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely re...

Transforming Growth Factor beta - A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducin...

Transforming Growth Factor beta1 - A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is s...

Transforming Growth Factor beta2 - A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits th...

Transforming Growth Factor beta3 - A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic...

Transforming Growth Factors - Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-t...

Transient Receptor Potential Channels - A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homolo...

Transmembrane Activator and CAML Interactor Protein - A tumor necrosis factor receptor superfamily member found expressed on peripheral B-LYMPHOCYTES. It ...

Trichosanthin - Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-...

Triptorelin - A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE with D-tryptophan substitut...

Tristetraprolin - A ZINC FINGER MOTIF containing transcription factor that was originally identified as one of the IMM...

Tropocollagen - The molecular unit of collagen fibrils that consist of repeating three-stranded polypeptide units ar...

Tropoelastin - A salt-soluble precursor of elastin. Lysyl oxidase is instrumental in converting it to elastin in co...

Tropomodulin - An actin capping protein that binds to the pointed-end of ACTIN. It functions in the presence of TRO...

Tropomyosin - A protein found in the thin filaments of muscle fibers. It inhibits contraction of the muscle unless...

Troponin - One of the minor protein components of skeletal muscle. Its function is to serve as the calcium-bind...

Troponin C - One of the three polypeptide chains that make up the TROPONIN complex of skeletal muscle. It is a ca...

Troponin I - One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin in...

Troponin T - One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific prot...

TRPC Cation Channels - A subgroup of TRP cation channels that contain 3-4 ANKYRIN repeats and a conserved C-terminal domain...

TRPM Cation Channels - A subgroup of TRP cation channels named after melastatin protein. They have the TRP domain but lack ...

TRPP Cation Channels - A subgroup of TRP cation channels that are widely expressed in various cell types. Defects are assoc...

TRPV Cation Channels - A subgroup of TRP cation channels named after vanilloid receptor. They are very sensitive to TEMPERA...

Truncated Hemoglobins - A family of hemoglobin-like proteins found in BACTERIA; PLANTS; and unicellular eukaryotes. Truncate...

Trypsin Inhibitor, Bowman-Birk Soybean - A low-molecular-weight protein (minimum molecular weight 8000) which has the ability to inhibit tryp...

Trypsin Inhibitor, Kazal Pancreatic - A pancreatic trypsin inhibitor common to all mammals. It is secreted with the zymogens into the panc...

Trypsin Inhibitor, Kunitz Soybean - A high-molecular-weight protein (approximately 22,500) containing 198 amino acid residues. It is a s...

Tubulin - A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolate...

Tuftsin - N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by e...

Tumor Necrosis Factor Decoy Receptors - A subclass of tumor necrosis family receptors that lack cell signaling domains. They bind to specifi...

Tumor Necrosis Factor Ligand Superfamily Member 13 - A member of tumor necrosis factor superfamily found on MACROPHAGES; DENDRITIC CELLS and T-LYMPHOCYTE...

Tumor Necrosis Factor Ligand Superfamily Member 14 - A member of tumor necrosis factor superfamily found on activated LYMPHOCYTES and MONOCYTES. It occur...

Tumor Necrosis Factor Ligand Superfamily Member 15 - A member of tumor necrosis factor superfamily found on ENDOTHELIAL CELLS that plays a role in the in...

Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - Intracellular signaling peptides and proteins that bind directly or indirectly to the cytoplasmic po...

Tumor Necrosis Factor-alpha - Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It ...

Tumor Necrosis Factors - A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS...

Tumor Suppressor Protein p14ARF - A gene product of the p16 tumor suppressor gene (GENES, P16). It antagonizes the function of MDM2 PR...

Tumor Suppressor Protein p53 - Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL...

Tumor Suppressor Proteins - Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormaliti...

Twist Transcription Factor - A basic helix-loop-helix transcription factor that was originally identified in DROSOPHILA as essent...

TYK2 Kinase - A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The...

Tyrosine 3-Monooxygenase - An enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydr...

Ubiquitin - A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a m...

Ubiquitin C - A single protein comprised of tandem repeats of the UBIQUITIN 78-amino acid sequence. It is a produc...

Ubiquitinated Proteins - Proteins covalently modified with UBIQUITINS or UBIQUITIN-LIKE PROTEINS....

Ubiquitins - A family of proteins that are structurally-related to Ubiquitin. Ubiquitins and ubiquitin-like prote...

Upstream Stimulatory Factors - Ubiquitously expressed basic HELIX-LOOP-HELIX MOTIF transcription factors. They bind CANNTG sequence...

Urokinase-Type Plasminogen Activator - A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is be...

Uteroglobin - A protein fraction of pregnant uterine fluid which can induce and regulate blastocystic development....

Utrophin - An autosomally-encoded 376-kDa cytoskeletal protein that is similar in structure and function to DYS...

Vaccines, DNA - Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. T...

Vaccines, Edible - Vaccines or candidate vaccines derived from edible plants. Transgenic plants (PLANTS, TRANSGENIC) ar...

Vaccines, Synthetic - Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines m...

Vaccines, Virosome - Vaccines using VIROSOMES as the antigen delivery system that stimulates the desired immune response....

Vacuolar Proton-Translocating ATPases - Proton-translocating ATPases that are involved in acidification of a variety of intracellular compar...

Variant Surface Glycoproteins, Trypanosoma - Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amin...

Vascular Cell Adhesion Molecule-1 - Cytokine-induced cell adhesion molecule present on activated endothelial cells, tissue macrophages, ...

Vascular Endothelial Growth Factor A - The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHE...

Vascular Endothelial Growth Factor B - A vascular endothelial growth factor expressed in a variety of tissues. It binds with high specifici...

Vascular Endothelial Growth Factor C - A vascular endothelial growth factor that specifically binds to VASCULAR ENDOTHELIAL GROWTH FACTOR R...

Vascular Endothelial Growth Factor D - A vascular endothelial growth factor that specifically binds to VASCULAR ENDOTHELIAL GROWTH FACTOR R...

Vascular Endothelial Growth Factor Receptor-1 - A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis an...

Vascular Endothelial Growth Factor Receptor-2 - A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in en...

Vascular Endothelial Growth Factor Receptor-3 - A vascular endothelial cell growth factor receptor whose expression is restricted primarily to adult...

Vascular Endothelial Growth Factor, Endocrine-Gland-Derived - A vascular endothelial growth factor whose expression is found largely restricted to the GONADS; ADR...

Vascular Endothelial Growth Factors - A family of angiogenic proteins that are closely-related to VASCULAR ENDOTHELIAL GROWTH FACTOR A. Th...

Vasoactive Intestinal Peptide - A highly basic, 28 amino acid neuropeptide released from intestinal mucosa. It has a wide range of b...

Vasopressins - Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with spec...

Vault Ribonucleoprotein Particles - Large cytoplasmic ribonucleoprotein particles that have an eight-fold symmetry with a central pore a...

Vegetable Proteins - Proteins which are present in or isolated from vegetables or vegetable products used as food. The co...

Ventricular Myosins - Isoforms of MYOSIN TYPE II, specifically found in the ventricular muscle of the HEART. Defects in th...

Versicans - HYALURONAN-containing proteoglycans found in the EXTRACELLULAR MATRIX of a variety of tissues and or...

Vesicle-Associated Membrane Protein 1 - A member of the vesicle-associated membrane protein family involved in the MEMBRANE FUSION of TRANSP...

Vesicle-Associated Membrane Protein 2 - A synaptic membrane protein involved in MEMBRANE FUSION of SYNAPTIC VESICLES with the presynaptic me...

Vesicle-Associated Membrane Protein 3 - A member of the vesicle associated membrane protein family. It has a broad tissue distribution and i...

Vesicular Acetylcholine Transport Proteins - Vesicular amine transporter proteins that transport the neurotransmitter ACETYLCHOLINE into small SE...

Vesicular Biogenic Amine Transport Proteins - Integral membrane proteins of the LIPID BILAYER of SECRETORY VESICLES that catalyze transport and st...

Vesicular Glutamate Transport Protein 1 - A vesicular glutamate transporter protein that is predominately expressed in TELENCEPHALON of the BR...

Vesicular Glutamate Transport Protein 2 - A vesicular glutamate transporter protein that is predominately expressed in the DIENCEPHALON and lo...

Vesicular Glutamate Transport Proteins - A family of vesicular neurotransmitter transporter proteins that were originally characterized as so...

Vesicular Inhibitory Amino Acid Transport Proteins - A family of vesicular neurotransmitter transporter proteins that sequester the inhibitory neurotrans...

Vesicular Monoamine Transport Proteins - A family of vesicular amine transporter proteins that catalyze the transport and storage of CATECHOL...

Vesicular Neurotransmitter Transport Proteins - A family of neurotransmitter transporter proteins that are INTEGRAL MEMBRANE PROTEINS of the LIPID B...

Vesicular Transport Proteins - A broad category of proteins involved in the formation, transport and dissolution of TRANSPORT VESIC...

vif Gene Products, Human Immunodeficiency Virus - Proteins encoded by the VIF GENES of the HUMAN IMMUNODEFICIENCY VIRUS....

Vimentin - An intermediate filament protein found in most differentiating cells, in cells grown in tissue cultu...

Vinculin - A cytoskeletal protein associated with cell-cell and cell-matrix interactions. The amino acid sequen...

Viral Core Proteins - Proteins found mainly in icosahedral DNA and RNA viruses. They consist of proteins directly associat...

Viral Envelope Proteins - Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelo...

Viral Fusion Proteins - Proteins, usually glycoproteins, found in the viral envelopes of a variety of viruses. They promote ...

Viral Matrix Proteins - Proteins associated with the inner surface of the lipid bilayer of the viral envelope. These protein...

Viral Nonstructural Proteins - Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged ...

Viral Proteins - Proteins found in any species of virus....

Viral Regulatory and Accessory Proteins - A broad category of viral proteins that play indirect roles in the biological processes and activiti...

Viral Structural Proteins - Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleoc...

Viral Tail Proteins - Proteins found in the tail sections of DNA and RNA viruses. It is believed that these proteins play ...

Vitamin D-Binding Protein - An alpha-globulin found in the plasma of man and other vertebrates. It is apparently synthesized in ...

Vitellins - Major egg yolk proteins from egg-laying animals such as non-mammalian VERTEBRATES; ARTHROPODS; and o...

Vitellogenins - Phospholipoglycoproteins produced in the fat body of egg-laying animals such as non-mammalian VERTEB...

Vitronectin - A blood plasma glycoprotein that mediates cell adhesion and interacts with proteins of the complemen...

Voltage-Dependent Anion Channel 1 - Voltage-dependent anion channel 1 is the major pore-forming protein of the mitochondrial outer membr...

Voltage-Dependent Anion Channel 2 - Voltage-dependent anion channel 2 is a low abundance mammalian isoform of VDAC that interacts with t...

Voltage-Dependent Anion Channels - A family of voltage-gated eukaryotic porins that form aqueous channels. They play an essential role ...

Von Hippel-Lindau Tumor Suppressor Protein - A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FA...

von Willebrand Factor - A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is pa...

vpr Gene Products, Human Immunodeficiency Virus - Proteins encoded by the VPR GENES of the HUMAN IMMUNODEFICIENCY VIRUS....

Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate - The lectin wheatgerm agglutinin conjugated to the enzyme HORSERADISH PEROXIDASE. It is widely used f...

Wheat Germ Agglutinins - Lectins purified from the germinating seeds of common wheat (Triticum vulgare); these bind to certai...

Winged-Helix Transcription Factors - A subfamily of HELIX-TURN-HELIX DNA-binding proteins that contain a variable length loop adjacent to...

Wiskott-Aldrich Syndrome Protein - WASP protein is mutated in WISKOTT-ALDRICH SYNDROME and is expressed primarily in hematopoietic cell...

Wiskott-Aldrich Syndrome Protein Family - A family of microfilament proteins whose name derives from the fact that mutations in members of thi...

Wiskott-Aldrich Syndrome Protein, Neuronal - A member of the Wiskott-Aldrich syndrome protein family that is found at high levels in NERVE CELLS....

Wnt Proteins - Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND...

Wnt1 Protein - A proto-oncogene protein and member of the Wnt family of proteins. It is expressed in the caudal MID...

Wnt2 Protein - A proto-oncogene protein and member of the Wnt family of proteins. It is frequently up-regulated in ...

WT1 Proteins - Isoforms encoded by the WT1 Wilms tumor suppressor gene (GENES, WILMS TUMOR) and produced by alterna...

Xedar Receptor - An ectodysplasin receptor subtype that is specific for ECTODYSPLASIN A2. Unlike the EDAR RECEPTOR th...

Xenopus Proteins - Proteins obtained from various species of Xenopus. Included here are proteins from the African claw...

Xeroderma Pigmentosum Group A Protein - A ZINC FINGER MOTIF protein that recognizes and interacts with damaged DNA. It is a DNA-binding prot...

Xeroderma Pigmentosum Group D Protein - A DNA helicase that is a component of TRANSCRIPTION FACTOR TFIIH. It plays an essential role in NUCL...

X-Linked Inhibitor of Apoptosis Protein - An inhibitor of apoptosis protein that is translated by a rare cap-independent mechanism. It blocks ...

Y-Box-Binding Protein 1 - Y-box-binding protein 1 was originally identified as a DNA-binding protein that interacts with Y-box...

YY1 Transcription Factor - A ubiquitously expressed zinc finger-containing protein that acts both as a repressor and activator ...

ZAP-70 Protein-Tyrosine Kinase - A protein tyrosine kinase that is required for T-CELL development and T-CELL ANTIGEN RECEPTOR functi...

Zebrafish Proteins - Proteins obtained from the ZEBRAFISH. Many of the proteins in this species have been the subject of ...

Zein - A group of alcohol-soluble seed storage proteins from the endosperm of corn....

zeta-Crystallins - A group of crystallins that have been found in the lens (LENS, CRYSTALLINE) of certain species of VE...

zeta-Globins - A member of the alpha-globin family. In humans, zeta-globin is encoded in the alpha-globin gene clus...

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Common Chronic Illnesses

Coronary Disease

An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Diabetes Mellitus, Type 1

A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
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Diabetes Mellitus, Type 2

A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
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Hypertension

Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Mesothelioma

A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)

Osteoarthritis

A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

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